sustained Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Similar Terms
Downloads & Tools

Genes

428 genes co-occuring with the biological term sustained in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACE2 angiotensin I converting enzyme 2
ACOT13 acyl-CoA thioesterase 13
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADIPOQ adiponectin, C1Q and collagen domain containing
ADRB1 adrenoceptor beta 1
AGTR1 angiotensin II receptor, type 1
AHR aryl hydrocarbon receptor
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALK anaplastic lymphoma receptor tyrosine kinase
AMHR2 anti-Mullerian hormone receptor, type II
ANK1 ankyrin 1, erythrocytic
ANXA2 annexin A2
ANXA7 annexin A7
APLP2 amyloid beta (A4) precursor-like protein 2
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AQP1 aquaporin 1 (Colton blood group)
AR androgen receptor
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ATF3 activating transcription factor 3
ATF6 activating transcription factor 6
ATG13 autophagy related 13
ATM ATM serine/threonine kinase
ATP13A2 ATPase type 13A2
ATR ATR serine/threonine kinase
AURKB aurora kinase B
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BCHE butyrylcholinesterase
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCR breakpoint cluster region
BDNF brain-derived neurotrophic factor
BIRC3 baculoviral IAP repeat containing 3
BLNK B-cell linker
BMP2 bone morphogenetic protein 2
BMP7 bone morphogenetic protein 7
BRAF B-Raf proto-oncogene, serine/threonine kinase
CASR calcium-sensing receptor
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCNB1 cyclin B1
CCNE1 cyclin E1
CCR4 chemokine (C-C motif) receptor 4
CD28 CD28 molecule
CD37 CD37 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD4 CD4 molecule
CD40LG CD40 ligand
CD63 CD63 molecule
CD80 CD80 molecule
CD86 CD86 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDK2 cyclin-dependent kinase 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDX1 caudal type homeobox 1
CFL2 cofilin 2 (muscle)
CFLAR CASP8 and FADD-like apoptosis regulator
CHD1L chromodomain helicase DNA binding protein 1-like
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CKM creatine kinase, muscle
CLDN11 claudin 11
COMP cartilage oligomeric matrix protein
COMT catechol-O-methyltransferase
CREB1 cAMP responsive element binding protein 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSC cathepsin C
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL9 chemokine (C-X-C motif) ligand 9
CXXC1 CXXC finger protein 1
CYBA cytochrome b-245, alpha polypeptide
CYLD cylindromatosis (turban tumor syndrome)
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYTH2 cytohesin 2
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DDIT4 DNA-damage-inducible transcript 4
DEFB103B defensin, beta 103B
DEFB4A defensin, beta 4A
DIABLO diablo, IAP-binding mitochondrial protein
DIO2 deiodinase, iodothyronine, type II
DISC1 disrupted in schizophrenia 1
DMD dystrophin
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9
DNM1L dynamin 1-like
DOCK8 dedicator of cytokinesis 8
DRD2 dopamine receptor D2
DRD4 dopamine receptor D4
DUOX2 dual oxidase 2
DUOXA2 dual oxidase maturation factor 2
DUSP1 dual specificity phosphatase 1
E2F1 E2F transcription factor 1
ECE1 endothelin converting enzyme 1
EDNRA endothelin receptor type A
EDNRB endothelin receptor type B
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
ENG endoglin
EP400 E1A binding protein p400
EPAS1 endothelial PAS domain protein 1
EPCAM epithelial cell adhesion molecule
EPHA8 EPH receptor A8
EPO erythropoietin
ERCC4 excision repair cross-complementation group 4
ERN1 endoplasmic reticulum to nucleus signaling 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
F2 coagulation factor II (thrombin)
F2R coagulation factor II (thrombin) receptor
F2RL1 coagulation factor II (thrombin) receptor-like 1
F2RL3 coagulation factor II (thrombin) receptor-like 3
F3 coagulation factor III (thromboplastin, tissue factor)
F5 coagulation factor V (proaccelerin, labile factor)
FAM65B family with sequence similarity 65, member B
FASLG Fas ligand (TNF superfamily, member 6)
FBXO7 F-box protein 7
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FGF2 fibroblast growth factor 2 (basic)
FGF23 fibroblast growth factor 23
FGF7 fibroblast growth factor 7
FGFR2 fibroblast growth factor receptor 2
FGFR4 fibroblast growth factor receptor 4
FHOD1 formin homology 2 domain containing 1
FLT3 fms-related tyrosine kinase 3
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXM1 forkhead box M1
FOXP3 forkhead box P3
FTO fat mass and obesity associated
GAB1 GRB2-associated binding protein 1
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GATA2 GATA binding protein 2
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GC group-specific component (vitamin D binding protein)
GCH1 GTP cyclohydrolase 1
GDNF glial cell derived neurotrophic factor
GFI1B growth factor independent 1B transcription repressor
GH1 growth hormone 1
GHRL ghrelin/obestatin prepropeptide
GJA1 gap junction protein, alpha 1, 43kDa
GLP2R glucagon-like peptide 2 receptor
GNRHR gonadotropin-releasing hormone receptor
GP6 glycoprotein VI (platelet)
GPER1 G protein-coupled estrogen receptor 1
GPR55 G protein-coupled receptor 55
GRAP2 GRB2-related adaptor protein 2
GRIK5 glutamate receptor, ionotropic, kainate 5
GRPR gastrin-releasing peptide receptor
GSK3B glycogen synthase kinase 3 beta
GSTM1 glutathione S-transferase mu 1
H2AFZ H2A histone family, member Z
HDAC2 histone deacetylase 2
HDAC3 histone deacetylase 3
HDAC5 histone deacetylase 5
HFE hemochromatosis
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIST2H3C histone cluster 2, H3c
HLA-A major histocompatibility complex, class I, A
HLA-C major histocompatibility complex, class I, C
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-E major histocompatibility complex, class I, E
HMGB1 high mobility group box 1
HMOX1 heme oxygenase 1
HRAS Harvey rat sarcoma viral oncogene homolog
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSF1 heat shock transcription factor 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HYAL2 hyaluronoglucosaminidase 2
ICAM1 intercellular adhesion molecule 1
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFI16 interferon, gamma-inducible protein 16
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IFNL3 interferon, lambda 3
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGFBP4 insulin-like growth factor binding protein 4
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL10 interleukin 10
IL11 interleukin 11
IL17A interleukin 17A
IL1B interleukin 1, beta
IL2 interleukin 2
IL27 interleukin 27
IL3 interleukin 3
IL33 interleukin 33
IL5 interleukin 5
IL6 interleukin 6
IL7R interleukin 7 receptor
INS insulin
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
JAK2 Janus kinase 2
JPH1 junctophilin 1
JPH2 junctophilin 2
JUN jun proto-oncogene
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KCNK3 potassium channel, two pore domain subfamily K, member 3
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KDM4B lysine (K)-specific demethylase 4B
KDR kinase insert domain receptor
KIAA1524 KIAA1524
KIDINS220 kinase D-interacting substrate, 220kDa
KIF11 kinesin family member 11
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KISS1 KiSS-1 metastasis-suppressor
KISS1R KISS1 receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KITLG KIT ligand
KLF5 Kruppel-like factor 5 (intestinal)
KLK1 kallikrein 1
KRAS Kirsten rat sarcoma viral oncogene homolog
L1CAM L1 cell adhesion molecule
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LEF1 lymphoid enhancer-binding factor 1
LEP leptin
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS9 lectin, galactoside-binding, soluble, 9
LMO2 LIM domain only 2 (rhombotin-like 1)
LRP5 low density lipoprotein receptor-related protein 5
LTA lymphotoxin alpha
LTB lymphotoxin beta (TNF superfamily, member 3)
LTB4R leukotriene B4 receptor
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3)
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP3K3 mitogen-activated protein kinase kinase kinase 3
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MBL2 mannose-binding lectin (protein C) 2, soluble
MCL1 myeloid cell leukemia 1
MCU mitochondrial calcium uniporter
MET MET proto-oncogene, receptor tyrosine kinase
MFI2 antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
MICU1 mitochondrial calcium uptake 1
MID1 midline 1
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR1275 microRNA 1275
MIR132 microRNA 132
MIR192 microRNA 192
MIR19A microRNA 19a
MIR21 microRNA 21
MIR27A microRNA 27a
MIR548M microRNA 548m
MLANA melan-A
MMP1 matrix metallopeptidase 1
MSLN mesothelin
MSS51 MSS51 mitochondrial translational activator
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO5B myosin VB
MYOG myogenin (myogenic factor 4)
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGFR nerve growth factor receptor
NLRP3 NLR family, pyrin domain containing 3
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NOX1 NADPH oxidase 1
NOX4 NADPH oxidase 4
NOX5 NADPH oxidase, EF-hand calcium binding domain 5
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR4A2 nuclear receptor subfamily 4, group A, member 2
NT5E 5'-nucleotidase, ecto (CD73)
NUDC nudC nuclear distribution protein
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PCNA proliferating cell nuclear antigen
PDE1A phosphodiesterase 1A, calmodulin-dependent
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDX1 pancreatic and duodenal homeobox 1
PF4 platelet factor 4
PGF placental growth factor
PGM1 phosphoglucomutase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLK2 polo-like kinase 2
PLK4 polo-like kinase 4
PML promyelocytic leukemia
PNPLA3 patatin-like phospholipase domain containing 3
PON1 paraoxonase 1
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PPP4R1 protein phosphatase 4, regulatory subunit 1
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKD1 protein kinase D1
PRKD2 protein kinase D2
PSEN1 presenilin 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTK2 protein tyrosine kinase 2
PTK6 protein tyrosine kinase 6
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RBP4 retinol binding protein 4, plasma
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RHOA ras homolog family member A
RIT1 Ras-like without CAAX 1
ROR1 receptor tyrosine kinase-like orphan receptor 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RYR3 ryanodine receptor 3
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
S1PR1 sphingosine-1-phosphate receptor 1
SALL4 spalt-like transcription factor 4
SCN1A sodium channel, voltage gated, type I alpha subunit
SCN4A sodium channel, voltage gated, type IV alpha subunit
SELE selectin E
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SFRP1 secreted frizzled-related protein 1
SGPL1 sphingosine-1-phosphate lyase 1
SHH sonic hedgehog
SIRT1 sirtuin 1
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SMAD3 SMAD family member 3
SNAI1 snail family zinc finger 1
SNAI2 snail family zinc finger 2
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SOD1 superoxide dismutase 1, soluble
SOS1 son of sevenless homolog 1 (Drosophila)
SPHK1 sphingosine kinase 1
SPP1 secreted phosphoprotein 1
SPRY2 sprouty homolog 2 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT4 signal transducer and activator of transcription 4
STOML2 stomatin (EPB72)-like 2
SULF1 sulfatase 1
TACR1 tachykinin receptor 1
TACR2 tachykinin receptor 2
TACR3 tachykinin receptor 3
TCF3 transcription factor 3
TCF7 transcription factor 7 (T-cell specific, HMG-box)
TEC tec protein tyrosine kinase
TGFB1 transforming growth factor, beta 1
TGFBR1 transforming growth factor, beta receptor 1
TGM2 transglutaminase 2
THRB thyroid hormone receptor, beta
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1
TLR4 toll-like receptor 4
TNC tenascin C
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TP53 tumor protein p53
TPSAB1 tryptase alpha/beta 1
TREM1 triggering receptor expressed on myeloid cells 1
TRIM26 tripartite motif containing 26
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TTK TTK protein kinase
UBR1 ubiquitin protein ligase E3 component n-recognin 1
ULK1 unc-51 like autophagy activating kinase 1
ULK2 unc-51 like autophagy activating kinase 2
URI1 URI1, prefoldin-like chaperone
VAV3 vav 3 guanine nucleotide exchange factor
VEGFA vascular endothelial growth factor A
VIM vimentin
VWF von Willebrand factor
WEE1 WEE1 G2 checkpoint kinase
XAF1 XIAP associated factor 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase