suxibuzone-5806 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the suxibuzone-5806 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ALDOB aldolase B, fructose-bisphosphate
AMDHD2 amidohydrolase domain containing 2
ANKRD26 ankyrin repeat domain 26
APC adenomatous polyposis coli
ARTN artemin
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
BAGE B melanoma antigen
C22ORF46 chromosome 22 open reading frame 46
C8ORF60 chromosome 8 open reading frame 60
C9ORF156 chromosome 9 open reading frame 156
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CCNT2 cyclin T2
CFLAR CASP8 and FADD-like apoptosis regulator
CGREF1 cell growth regulator with EF-hand domain 1
CNGB3 cyclic nucleotide gated channel beta 3
CPA1 carboxypeptidase A1 (pancreatic)
CRMP1 collapsin response mediator protein 1
CRYBB2P1 crystallin, beta B2 pseudogene 1
DCAF8 DDB1 and CUL4 associated factor 8
DIAPH2 diaphanous-related formin 2
EHBP1L1 EH domain binding protein 1-like 1
ELMO2 engulfment and cell motility 2
FGFR1 fibroblast growth factor receptor 1
FGL1 fibrinogen-like 1
FNDC3A fibronectin type III domain containing 3A
GAS8 growth arrest-specific 8
GMEB1 glucocorticoid modulatory element binding protein 1
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GSTCD glutathione S-transferase, C-terminal domain containing
HIC2 hypermethylated in cancer 2
HOXC10 homeobox C10
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCTD13 potassium channel tetramerization domain containing 13
KLF13 Kruppel-like factor 13
KRT19P2 keratin 19 pseudogene 2
LPAR2 lysophosphatidic acid receptor 2
MAN2A2 mannosidase, alpha, class 2A, member 2
MCTP2 multiple C2 domains, transmembrane 2
MEF2D myocyte enhancer factor 2D
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MTM1 myotubularin 1
MYH14 myosin, heavy chain 14, non-muscle
MYOF myoferlin
NEK1 NIMA-related kinase 1
NEUROD1 neuronal differentiation 1
NFATC4 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
NPTXR neuronal pentraxin receptor
NRP2 neuropilin 2
OGFR opioid growth factor receptor
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PEX5L peroxisomal biogenesis factor 5-like
PHC1 polyhomeotic homolog 1 (Drosophila)
PHKG1 phosphorylase kinase, gamma 1 (muscle)
PLSCR2 phospholipid scramblase 2
PMEL premelanosome protein
PNMAL1 paraneoplastic Ma antigen family-like 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRB1 proline-rich protein BstNI subfamily 1
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RBPMS RNA binding protein with multiple splicing
REEP1 receptor accessory protein 1
RPL10 ribosomal protein L10
SAMD4A sterile alpha motif domain containing 4A
SCAMP1 secretory carrier membrane protein 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SGSM3 small G protein signaling modulator 3
SLC22A18 solute carrier family 22, member 18
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SOS2 son of sevenless homolog 2 (Drosophila)
STS steroid sulfatase (microsomal), isozyme S
TBC1D30 TBC1 domain family, member 30
TBL1Y transducin (beta)-like 1, Y-linked
TBX10 T-box 10
TEX40 testis expressed 40
TFCP2L1 transcription factor CP2-like 1
TMCC1 transmembrane and coiled-coil domain family 1
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TPM1 tropomyosin 1 (alpha)
TPST2 tyrosylprotein sulfotransferase 2
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSKU tsukushi, small leucine rich proteoglycan
TUBA4B tubulin, alpha 4b
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast)
WDFY3 WD repeat and FYVE domain containing 3
WDR25 WD repeat domain 25
WIPF1 WAS/WASL interacting protein family, member 1
YY1 YY1 transcription factor
ZNF214 zinc finger protein 214
ZNF324 zinc finger protein 324
ZNF614 zinc finger protein 614
ZNF688 zinc finger protein 688

decreased expression

Symbol Name
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
ALS2CL ALS2 C-terminal like
ARMC7 armadillo repeat containing 7
BHLHB9 basic helix-loop-helix domain containing, class B, 9
BNC2 basonuclin 2
C16ORF62 chromosome 16 open reading frame 62
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CNPY3 canopy FGF signaling regulator 3
COPG1 coatomer protein complex, subunit gamma 1
CPEB1 cytoplasmic polyadenylation element binding protein 1
CRABP2 cellular retinoic acid binding protein 2
CTSO cathepsin O
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
DOCK1 dedicator of cytokinesis 1
DPM2 dolichyl-phosphate mannosyltransferase polypeptide 2, regulatory subunit
E2F1 E2F transcription factor 1
ECI1 enoyl-CoA delta isomerase 1
EDC3 enhancer of mRNA decapping 3
FAM193B family with sequence similarity 193, member B
FAM53B family with sequence similarity 53, member B
FPGS folylpolyglutamate synthase
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPS2 G protein pathway suppressor 2
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIRA histone cell cycle regulator
HIST1H1T histone cluster 1, H1t
HIST1H2BC histone cluster 1, H2bc
HIST1H2BE histone cluster 1, H2be
HIST2H2AA3 histone cluster 2, H2aa3
HLX H2.0-like homeobox
HMOX1 heme oxygenase 1
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HYAL3 hyaluronoglucosaminidase 3
IL17RB interleukin 17 receptor B
IRF6 interferon regulatory factor 6
ITM2C integral membrane protein 2C
KCTD7 potassium channel tetramerization domain containing 7
KIFAP3 kinesin-associated protein 3
KLF2 Kruppel-like factor 2
LONRF3 LON peptidase N-terminal domain and ring finger 3
LPAR6 lysophosphatidic acid receptor 6
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LZTR1 leucine-zipper-like transcription regulator 1
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MYLK myosin light chain kinase
NBAS neuroblastoma amplified sequence
NHEJ1 nonhomologous end-joining factor 1
OGFRL1 opioid growth factor receptor-like 1
OLFML2A olfactomedin-like 2A
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PACS1 phosphofurin acidic cluster sorting protein 1
PAN2 PAN2 poly(A) specific ribonuclease subunit
PCSK7 proprotein convertase subtilisin/kexin type 7
PDIA3 protein disulfide isomerase family A, member 3
PHACTR4 phosphatase and actin regulator 4
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PKN1 protein kinase N1
PLCD1 phospholipase C, delta 1
PLEKHA6 pleckstrin homology domain containing, family A member 6
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRR15L proline rich 15-like
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
PTK6 protein tyrosine kinase 6
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RBM42 RNA binding motif protein 42
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RNF126P1 ring finger protein 126 pseudogene 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPH3AL rabphilin 3A-like (without C2 domains)
SAMD9 sterile alpha motif domain containing 9
SLC27A3 solute carrier family 27 (fatty acid transporter), member 3
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC38A10 solute carrier family 38, member 10
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SMU1 smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans)
SNTA1 syntrophin, alpha 1
SREK1IP1 SREK1-interacting protein 1
STAC SH3 and cysteine rich domain
STBD1 starch binding domain 1
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TRAPPC6A trafficking protein particle complex 6A
UROS uroporphyrinogen III synthase
VASP vasodilator-stimulated phosphoprotein
WDR46 WD repeat domain 46
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF264 zinc finger protein 264
ZNF331 zinc finger protein 331
ZNF652 zinc finger protein 652
ZNF8 zinc finger protein 8