suxibuzone-7163 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the suxibuzone-7163 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABI2 abl-interactor 2
ADCY6 adenylate cyclase 6
AHCYL2 adenosylhomocysteinase-like 2
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ATM ATM serine/threonine kinase
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide
BMP1 bone morphogenetic protein 1
C11ORF21 chromosome 11 open reading frame 21
C6ORF47 chromosome 6 open reading frame 47
CALCOCO1 calcium binding and coiled-coil domain 1
CCDC134 coiled-coil domain containing 134
CCDC186 coiled-coil domain containing 186
CCNO cyclin O
CD209 CD209 molecule
CD44 CD44 molecule (Indian blood group)
CDC25C cell division cycle 25C
CDC42 cell division cycle 42
CEP250 centrosomal protein 250kDa
CPPED1 calcineurin-like phosphoesterase domain containing 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
DMTN dematin actin binding protein
DOCK9 dedicator of cytokinesis 9
DSC3 desmocollin 3
DSCAM Down syndrome cell adhesion molecule
DYSF dysferlin
ELOVL5 ELOVL fatty acid elongase 5
EPHA1 EPH receptor A1
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM131A family with sequence similarity 131, member A
FGF2 fibroblast growth factor 2 (basic)
FGFR4 fibroblast growth factor receptor 4
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
GOLGA8A golgin A8 family, member A
GON4L gon-4-like (C. elegans)
HOXC4 homeobox C4
IDS iduronate 2-sulfatase
IFT140 intraflagellar transport 140
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
IL12RB1 interleukin 12 receptor, beta 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KLF9 Kruppel-like factor 9
KLHL25 kelch-like family member 25
LAMA4 laminin, alpha 4
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LYST lysosomal trafficking regulator
MKL1 megakaryoblastic leukemia (translocation) 1
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MPPE1 metallophosphoesterase 1
MUSK muscle, skeletal, receptor tyrosine kinase
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NDRG3 NDRG family member 3
NDUFAF5 NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
NEURL1 neuralized E3 ubiquitin protein ligase 1
NKX3-2 NK3 homeobox 2
NPFFR1 neuropeptide FF receptor 1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
NUP214 nucleoporin 214kDa
NUP88 nucleoporin 88kDa
PACS1 phosphofurin acidic cluster sorting protein 1
PIBF1 progesterone immunomodulatory binding factor 1
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLEC plectin
POFUT1 protein O-fucosyltransferase 1
POU4F1 POU class 4 homeobox 1
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRLR prolactin receptor
PRUNE2 prune homolog 2 (Drosophila)
PSG1 pregnancy specific beta-1-glycoprotein 1
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RABGAP1L RAB GTPase activating protein 1-like
RHOQ ras homolog family member Q
RIN2 Ras and Rab interactor 2
RTEL1 regulator of telomere elongation helicase 1
S100A4 S100 calcium binding protein A4
SCAND2P SCAN domain containing 2 pseudogene
SECTM1 secreted and transmembrane 1
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLC39A9 solute carrier family 39, member 9
SNCG synuclein, gamma (breast cancer-specific protein 1)
SOAT1 sterol O-acyltransferase 1
SOD2 superoxide dismutase 2, mitochondrial
SOX4 SRY (sex determining region Y)-box 4
SSPN sarcospan
STK17B serine/threonine kinase 17b
SYMPK symplekin
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TGFA transforming growth factor, alpha
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TLE2 transducin-like enhancer of split 2
TMEM231 transmembrane protein 231
TMOD1 tropomodulin 1
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
UBA6 ubiquitin-like modifier activating enzyme 6
UBE3B ubiquitin protein ligase E3B
VARS valyl-tRNA synthetase
VEGFB vascular endothelial growth factor B
WNT16 wingless-type MMTV integration site family, member 16
ZBTB14 zinc finger and BTB domain containing 14
ZNF362 zinc finger protein 362

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ASPHD1 aspartate beta-hydroxylase domain containing 1
AXIN1 axin 1
BEX4 brain expressed, X-linked 4
C14ORF132 chromosome 14 open reading frame 132
C7ORF43 chromosome 7 open reading frame 43
CAPN15 calpain 15
CEP97 centrosomal protein 97kDa
CFD complement factor D (adipsin)
CHKB choline kinase beta
CLDN9 claudin 9
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COBL cordon-bleu WH2 repeat protein
COCH cochlin
COL9A2 collagen, type IX, alpha 2
COQ6 coenzyme Q6 monooxygenase
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
FAM188A family with sequence similarity 188, member A
FAM86C1 family with sequence similarity 86, member C1
FANCF Fanconi anemia, complementation group F
FBXL15 F-box and leucine-rich repeat protein 15
FBXL6 F-box and leucine-rich repeat protein 6
FZD2 frizzled class receptor 2
GLB1L2 galactosidase, beta 1-like 2
GLI3 GLI family zinc finger 3
GNL1 guanine nucleotide binding protein-like 1
GPATCH3 G patch domain containing 3
GPRC5C G protein-coupled receptor, class C, group 5, member C
GRAMD4 GRAM domain containing 4
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H2AI histone cluster 1, H2ai
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
INPP5K inositol polyphosphate-5-phosphatase K
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF7 interferon regulatory factor 7
ISYNA1 inositol-3-phosphate synthase 1
JUNB jun B proto-oncogene
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KIAA0922 KIAA0922
KRT86 keratin 86, type II
MAP1S microtubule-associated protein 1S
MAPKBP1 mitogen-activated protein kinase binding protein 1
MAST3 microtubule associated serine/threonine kinase 3
MB myoglobin
NECAB3 N-terminal EF-hand calcium binding protein 3
NPM3 nucleophosmin/nucleoplasmin 3
NUPL2 nucleoporin like 2
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PMP22 peripheral myelin protein 22
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
RAB33B RAB33B, member RAS oncogene family
RAB8B RAB8B, member RAS oncogene family
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF123 ring finger protein 123
RPAP2 RNA polymerase II associated protein 2
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SGMS1 sphingomyelin synthase 1
SHPK sedoheptulokinase
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SMCO4 single-pass membrane protein with coiled-coil domains 4
SNORA21 small nucleolar RNA, H/ACA box 21
SNX16 sorting nexin 16
SOX12 SRY (sex determining region Y)-box 12
SSFA2 sperm specific antigen 2
STAG3 stromal antigen 3
STK16 serine/threonine kinase 16
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SUPT3H suppressor of Ty 3 homolog (S. cerevisiae)
SYNGR3 synaptogyrin 3
TCTN2 tectonic family member 2
TDRD7 tudor domain containing 7
TMEM115 transmembrane protein 115
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRAIP TRAF interacting protein
TTC30A tetratricopeptide repeat domain 30A
TUBA3C tubulin, alpha 3c
UBIAD1 UbiA prenyltransferase domain containing 1
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZBED1 zinc finger, BED-type containing 1
ZBED8 zinc finger, BED-type containing 8
ZDHHC24 zinc finger, DHHC-type containing 24
ZFP36 ZFP36 ring finger protein
ZNF254 zinc finger protein 254
ZNF552 zinc finger protein 552
ZNHIT2 zinc finger, HIT-type containing 2