suz12_17339329_mouse_embryonic_stem_cell_es_cell_lof_mouse_gpl1261_gse31354 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations
Category transcriptomics
Type transcription factor perturbation
Description transcription factor perturbation identified as [TF gene symbol]_[publication PMID]_[cell or tissue]_[perturbation]_[organism]_[GEO platform]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE31354
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Genes

1075 genes differentially expressed following the suz12_17339329_mouse_embryonic_stem_cell_es_cell_lof_mouse_gpl1261_gse31354 transcription factor perturbation from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.

increased expression

Symbol Name Standardized Value
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 0.199338
HMCES 5-hydroxymethylcytosine (hmC) binding, ES cell-specific 0.199176
JAM2 junctional adhesion molecule 2 0.198911
MTF2 metal response element binding transcription factor 2 0.198881
EMP1 epithelial membrane protein 1 0.198822
TIPIN TIMELESS interacting protein 0.198366
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.197558
TOMM7 translocase of outer mitochondrial membrane 7 homolog (yeast) 0.197397
PNMA5 paraneoplastic Ma antigen family member 5 0.197367
OARD1 O-acyl-ADP-ribose deacylase 1 0.197309
RPS26 ribosomal protein S26 0.19662
SLC25A18 solute carrier family 25 (glutamate carrier), member 18 0.19468
CARS cysteinyl-tRNA synthetase 0.194323
IPMK inositol polyphosphate multikinase 0.194027
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 0.193567
PHACTR1 phosphatase and actin regulator 1 0.193538
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 0.193153
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 0.192473
CDCA8 cell division cycle associated 8 0.192068
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.192007
GOT1L1 glutamic-oxaloacetic transaminase 1-like 1 0.190957
SPP1 secreted phosphoprotein 1 0.190957
GSTP1 glutathione S-transferase pi 1 0.190822
YIF1B Yip1 interacting factor homolog B (S. cerevisiae) 0.190762
NAV2 neuron navigator 2 0.190433
MCM7 minichromosome maintenance complex component 7 0.188924
CCDC69 coiled-coil domain containing 69 0.188624
DLX4 distal-less homeobox 4 0.188487
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 0.188487
NEU3 sialidase 3 (membrane sialidase) 0.188396
WDR4 WD repeat domain 4 0.188321
GSTM2 glutathione S-transferase mu 2 (muscle) 0.188199
SDC4 syndecan 4 0.187065
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 0.186899
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 0.186733
ZNF655 zinc finger protein 655 0.186476
HRASLS HRAS-like suppressor 0.186401
MYB v-myb avian myeloblastosis viral oncogene homolog 0.186069
UBE2A ubiquitin-conjugating enzyme E2A 0.186039
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.185979
ALPI alkaline phosphatase, intestinal 0.184115
KLF9 Kruppel-like factor 9 0.182851
TET1 tet methylcytosine dioxygenase 1 0.182441
H2AFV H2A histone family, member V 0.181742
DHX16 DEAH (Asp-Glu-Ala-His) box polypeptide 16 0.181485
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9 0.18098
TMC6 transmembrane channel-like 6 0.180872
FRYL FRY-like 0.180411
KLF4 Kruppel-like factor 4 (gut) 0.179935
COX17 COX17 cytochrome c oxidase copper chaperone 0.179859
MMRN1 multimerin 1 0.179659
FMR1NB fragile X mental retardation 1 neighbor 0.179567
DCX doublecortin 0.179537
RPS3A ribosomal protein S3A 0.178894
C22ORF15 chromosome 22 open reading frame 15 0.178695
THTPA thiamine triphosphatase 0.178221
TSR2 TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) 0.177456
GATA4 GATA binding protein 4 0.177209
ERO1L ERO1-like (S. cerevisiae) 0.176436
RPS28 ribosomal protein S28 0.176189
SSR4 signal sequence receptor, delta 0.176127
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) 0.175479
GFRA2 GDNF family receptor alpha 2 0.17474
KCNK5 potassium channel, two pore domain subfamily K, member 5 0.17474
LMBR1L limb development membrane protein 1-like 0.17434
CROT carnitine O-octanoyltransferase 0.17411
SNX5 sorting nexin 5 0.173554
SDHAF1 succinate dehydrogenase complex assembly factor 1 0.173119
RBMXL2 RNA binding motif protein, X-linked-like 2 0.172497
BDKRB2 bradykinin receptor B2 0.172497
GDF3 growth differentiation factor 3 0.172094
NCOA4 nuclear receptor coactivator 4 0.17149
HSPB1 heat shock 27kDa protein 1 0.170361
MUCL1 mucin-like 1 0.170361
GDF11 growth differentiation factor 11 0.169678
NDUFA1 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa 0.169412
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 0.168694
SLC25A36 solute carrier family 25 (pyrimidine nucleotide carrier), member 36 0.168445
JARID2 jumonji, AT rich interactive domain 2 0.167837
MMS22L MMS22-like, DNA repair protein 0.167697
CALCOCO2 calcium binding and coiled-coil domain 2 0.167153
GJB1 gap junction protein, beta 1, 32kDa 0.16678
MPP1 membrane protein, palmitoylated 1, 55kDa 0.166718
BBS12 Bardet-Biedl syndrome 12 0.16647
VPS25 vacuolar protein sorting 25 homolog (S. cerevisiae) 0.166299
DPY30 dpy-30 homolog (C. elegans) 0.166206
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 0.165893
MKRN1 makorin ring finger protein 1 0.165783
NANOG Nanog homeobox 0.165281
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3 0.164451
SLC6A16 solute carrier family 6, member 16 0.164279
RPS19 ribosomal protein S19 0.164279
RPS15 ribosomal protein S15 0.164076
TRIM40 tripartite motif containing 40 0.163764
PCDHB11 protocadherin beta 11 0.163217
NODAL nodal growth differentiation factor 0.162641
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2 0.162267
RASSF3 Ras association (RalGDS/AF-6) domain family member 3 0.162188
JAG2 jagged 2 0.161983
DNAJB7 DnaJ (Hsp40) homolog, subfamily B, member 7 0.161983
MASTL microtubule associated serine/threonine kinase-like 0.1617
ACKR3 atypical chemokine receptor 3 0.160569
VPS26B vacuolar protein sorting 26 homolog B (S. pombe) 0.160428
TMEM64 transmembrane protein 64 0.159989
EXOC3L4 exocyst complex component 3-like 4 0.158784
FGF4 fibroblast growth factor 4 0.158581
IFITM2 interferon induced transmembrane protein 2 0.158471
CCDC138 coiled-coil domain containing 138 0.157746
GLOD5 glyoxalase domain containing 5 0.15688
DPPA5 developmental pluripotency associated 5 0.155513
TLE3 transducin-like enhancer of split 3 0.155231
RTEL1 regulator of telomere elongation helicase 1 0.154478
EDN3 endothelin 3 0.153893
FRRS1 ferric-chelate reductase 1 0.153846
PRR18 proline rich 18 0.152994
MIAT myocardial infarction associated transcript (non-protein coding) 0.151672
RPRD2 regulation of nuclear pre-mRNA domain containing 2 0.151672
HDAC6 histone deacetylase 6 0.151091
RC3H2 ring finger and CCCH-type domains 2 0.14975
BANF1 barrier to autointegration factor 1 0.14975
DOHH deoxyhypusine hydroxylase/monooxygenase 0.149229
LIMCH1 LIM and calponin homology domains 1 0.148677
PPEF2 protein phosphatase, EF-hand calcium binding domain 2 0.147843
UQCC1 ubiquinol-cytochrome c reductase complex assembly factor 1 0.147607
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.147434
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa 0.146457
ACAA2 acetyl-CoA acyltransferase 2 0.145288
CASZ1 castor zinc finger 1 0.144799
TDRD12 tudor domain containing 12 0.144484
POU5F1 POU class 5 homeobox 1 0.144137
MCM3 minichromosome maintenance complex component 3 0.143492
PML promyelocytic leukemia 0.14321
EPGN epithelial mitogen 0.142721
SLC25A39 solute carrier family 25, member 39 0.141205
PFKP phosphofructokinase, platelet 0.140716
GPX4 glutathione peroxidase 4 0.140165
KNTC1 kinetochore associated 1 0.139898
ULK1 unc-51 like autophagy activating kinase 1 0.13938
MYO1F myosin IF 0.139238
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 0.138481
DIABLO diablo, IAP-binding mitochondrial protein 0.138102
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 0.137755
DBR1 debranching RNA lariats 1 0.137645
C17ORF62 chromosome 17 open reading frame 62 0.137503
DPEP3 dipeptidase 3 0.137298
SGOL2 shugoshin-like 2 (S. pombe) 0.137267
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal) 0.137093
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.135883
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) 0.135161
PDLIM1 PDZ and LIM domain 1 0.133916
FAM184A family with sequence similarity 184, member A 0.133507
MRFAP1 Morf4 family associated protein 1 0.133051
HCRTR2 hypocretin (orexin) receptor 2 0.131264
CUX1 cut-like homeobox 1 0.130855
ASS1 argininosuccinate synthase 1 0.130415
C16ORF91 chromosome 16 open reading frame 91 0.1301
WDR5 WD repeat domain 5 0.1293
PIR pirin (iron-binding nuclear protein) 0.128455
MKLN1 muskelin 1, intracellular mediator containing kelch motifs 0.128283
SCLT1 sodium channel and clathrin linker 1 0.128033
DCLRE1B DNA cross-link repair 1B 0.127939
RPL23A ribosomal protein L23a 0.126216
KLHL15 kelch-like family member 15 0.125325
BCAT1 branched chain amino-acid transaminase 1, cytosolic 0.125091
DNMT3L DNA (cytosine-5-)-methyltransferase 3-like 0.125091
DDT D-dopachrome tautomerase 0.124327
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.124264
ATF4 activating transcription factor 4 0.123719
TMPRSS6 transmembrane protease, serine 6 0.123141
MYCBP MYC binding protein 0.121971
APLP1 amyloid beta (A4) precursor-like protein 1 0.121193
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 0.121084
RPL10 ribosomal protein L10 0.120913
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 0.120509
UBE2L6 ubiquitin-conjugating enzyme E2L 6 0.120198
ASPA aspartoacylase 0.119686
FIGN fidgetin 0.119141
PI4KB phosphatidylinositol 4-kinase, catalytic, beta 0.118706
TMPRSS5 transmembrane protease, serine 5 0.118256
GPA33 glycoprotein A33 (transmembrane) 0.118225
PCDHB16 protocadherin beta 16 0.117713
WDR20 WD repeat domain 20 0.117604
NHP2 NHP2 ribonucleoprotein 0.115918
SPICE1 spindle and centriole associated protein 1 0.11567
TRAK1 trafficking protein, kinesin binding 1 0.1155
BANK1 B-cell scaffold protein with ankyrin repeats 1 0.115407
BMP10 bone morphogenetic protein 10 0.112292
DAXX death-domain associated protein 0.110399
OSBPL3 oxysterol binding protein-like 3 0.109464
ACOX1 acyl-CoA oxidase 1, palmitoyl 0.108897
TET2 tet methylcytosine dioxygenase 2 0.108897
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 0.108484
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 0.10674
UBALD2 UBA-like domain containing 2 0.106145
CSNK2A2 casein kinase 2, alpha prime polypeptide 0.104775
BACE2 beta-site APP-cleaving enzyme 2 0.104638
OOEP oocyte expressed protein 0.103665
L3MBTL2 l(3)mbt-like 2 (Drosophila) 0.103513
POLE4 polymerase (DNA-directed), epsilon 4, accessory subunit 0.103437
RPL7A ribosomal protein L7a 0.103346
DIXDC1 DIX domain containing 1 0.102042
SLAIN2 SLAIN motif family, member 2 0.101936
TMEM151B transmembrane protein 151B 0.101285
HESX1 HESX homeobox 1 0.100847
PCCB propionyl CoA carboxylase, beta polypeptide 0.099624
AAMP angio-associated, migratory cell protein 0.09863
TBX19 T-box 19 0.098073
MLIP muscular LMNA-interacting protein 0.097413
GNPNAT1 glucosamine-phosphate N-acetyltransferase 1 0.097082
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 0.096587
SNHG8 small nucleolar RNA host gene 8 0.09515
THEMIS thymocyte selection associated 0.093807
FAM78A family with sequence similarity 78, member A 0.093673
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 0.093048
SLC22A14 solute carrier family 22, member 14 0.092334
TMEM107 transmembrane protein 107 0.091651
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa 0.091621
KLHL13 kelch-like family member 13 0.091592
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 0.090673
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.090096
UPP1 uridine phosphorylase 1 0.08983
CKM creatine kinase, muscle 0.08831
DKK2 dickkopf WNT signaling pathway inhibitor 2 0.088281
FAM25C family with sequence similarity 25, member C 0.087575
WDR89 WD repeat domain 89 0.087222
CISD1 CDGSH iron sulfur domain 1 0.086796
INO80E INO80 complex subunit E 0.086151
ADRB3 adrenoceptor beta 3 0.085961
ZMYND19 zinc finger, MYND-type containing 19 0.084134
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.083012
CLDN9 claudin 9 0.082925
C2CD4C C2 calcium-dependent domain containing 4C 0.082228
FZD6 frizzled class receptor 6 0.081836
TEX101 testis expressed 101 0.080823
CHD2 chromodomain helicase DNA binding protein 2 0.080693
SMTNL2 smoothelin-like 2 0.080505
SYCE2 synaptonemal complex central element protein 2 0.07984
NR5A2 nuclear receptor subfamily 5, group A, member 2 0.079552
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.079278
GABARAPL2 GABA(A) receptor-associated protein-like 2 0.078803
LSM3 LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.077855
CD9 CD9 molecule 0.077253
ESRRB estrogen-related receptor beta 0.076694
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase 0.075693
IFITM1 interferon induced transmembrane protein 1 0.075594
ARHGAP26 Rho GTPase activating protein 26 0.075309
DYNLT1 dynein, light chain, Tctex-type 1 0.075123
TXNIP thioredoxin interacting protein 0.074568
LENEP lens epithelial protein 0.07261
MRI1 methylthioribose-1-phosphate isomerase 1 0.071551
MCM2 minichromosome maintenance complex component 2 0.070495
IGSF23 immunoglobulin superfamily, member 23 0.069119
BEST1 bestrophin 1 0.068964
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.068866
FBL fibrillarin 0.067637
LACTB2 lactamase, beta 2 0.06508
CDC5L cell division cycle 5-like 0.064473
KLF2 Kruppel-like factor 2 0.063094
GM2A GM2 ganglioside activator 0.062874
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.062159
RPA2 replication protein A2, 32kDa 0.061461
TBCEL tubulin folding cofactor E-like 0.061379
UNG uracil-DNA glycosylase 0.061256
CCDC30 coiled-coil domain containing 30 0.061037
BOLA1 bolA family member 1 0.060601
MTCH2 mitochondrial carrier 2 0.059102
RBM11 RNA binding motif protein 11 0.058681
CNTROB centrobin, centrosomal BRCA2 interacting protein 0.058505
PARP1 poly (ADP-ribose) polymerase 1 0.058234
USP1 ubiquitin specific peptidase 1 0.057558
IRX4 iroquois homeobox 4 0.056143
FOXJ3 forkhead box J3 0.055699
ODF3 outer dense fiber of sperm tails 3 0.05472
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 0.054226
ACAT1 acetyl-CoA acetyltransferase 1 0.054167
CDC73 cell division cycle 73 0.053992
PBLD phenazine biosynthesis-like protein domain containing 0.053904
LAPTM5 lysosomal protein transmembrane 5 0.053641
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) 0.053318
SIN3A SIN3 transcription regulator family member A 0.053202
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa 0.052911
SLC13A1 solute carrier family 13 (sodium/sulfate symporter), member 1 0.052326
MSH2 mutS homolog 2 0.051686
URI1 URI1, prefoldin-like chaperone 0.051338
NOL8 nucleolar protein 8 0.050528
CNOT8 CCR4-NOT transcription complex, subunit 8 0.049229
RPL35 ribosomal protein L35 0.048566
MRPL15 mitochondrial ribosomal protein L15 0.04828
DTYMK deoxythymidylate kinase (thymidylate kinase) 0.048021
ENAH enabled homolog (Drosophila) 0.046763
CEP85 centrosomal protein 85kDa 0.046392
TBX6 T-box 6 0.045736
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.045366
PCDHB19P protocadherin beta 19 pseudogene 0.044913
AQP3 aquaporin 3 (Gill blood group) 0.044659
CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 0.04398
APOC1 apolipoprotein C-I 0.043557
IRF3 interferon regulatory factor 3 0.04302
MAGEB16 melanoma antigen family B16 0.042092
RAD21 RAD21 homolog (S. pombe) 0.042092
UBR4 ubiquitin protein ligase E3 component n-recognin 4 0.04008
C2ORF88 chromosome 2 open reading frame 88 0.039914
TCEA2 transcription elongation factor A (SII), 2 0.039774
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 0.039524
L2HGDH L-2-hydroxyglutarate dehydrogenase 0.039384
SLFN12 schlafen family member 12 0.038278
TCOF1 Treacher Collins-Franceschetti syndrome 1 0.03723
SHMT1 serine hydroxymethyltransferase 1 (soluble) 0.036817
GCLM glutamate-cysteine ligase, modifier subunit 0.036404
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) 0.03613
SMYD2 SET and MYND domain containing 2 0.035992
BCL2 B-cell CLL/lymphoma 2 0.035528
CLGN calmegin 0.034328
ISOC1 isochorismatase domain containing 1 0.034273
ELOVL6 ELOVL fatty acid elongase 6 0.034192
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 0.034083
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 0.03243
GSR glutathione reductase 0.032107
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 0.030654
H19 H19, imprinted maternally expressed transcript (non-protein coding) 0.030198
TDH L-threonine dehydrogenase (pseudogene) 0.029691
MSH6 mutS homolog 6 0.028201
APOL6 apolipoprotein L, 6 0.02791
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2 0.027883
SLC25A12 solute carrier family 25 (aspartate/glutamate carrier), member 12 0.02783
KIAA0586 KIAA0586 0.027406
ZMYND8 zinc finger, MYND-type containing 8 0.026905
NOS1 nitric oxide synthase 1 (neuronal) 0.02672
SUN1 Sad1 and UNC84 domain containing 1 0.026616
ARRDC5 arrestin domain containing 5 0.025669
SPDYA speedy/RINGO cell cycle regulator family member A 0.025434
TPD52 tumor protein D52 0.025302
FBXO15 F-box protein 15 0.025119
TNK2 tyrosine kinase, non-receptor, 2 0.023735
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.023632
WDR66 WD repeat domain 66 0.02345
BSN bassoon presynaptic cytomatrix protein 0.022672
MRPL19 mitochondrial ribosomal protein L19 0.022595
NONO non-POU domain containing, octamer-binding 0.021432
GPR150 G protein-coupled receptor 150 0.01872
USP9X ubiquitin specific peptidase 9, X-linked 0.018517
SNHG3 small nucleolar RNA host gene 3 0.018415
PRMT3 protein arginine methyltransferase 3 0.018262
DCAF13 DDB1 and CUL4 associated factor 13 0.017908
SLC6A17 solute carrier family 6 (neutral amino acid transporter), member 17 0.017834
HIRA histone cell cycle regulator 0.016899
KCNJ10 potassium channel, inwardly rectifying subfamily J, member 10 0.015816
RRM2 ribonucleotide reductase M2 0.015767
G2E3 G2/M-phase specific E3 ubiquitin protein ligase 0.015266
COX5B cytochrome c oxidase subunit Vb 0.014619
ZNF296 zinc finger protein 296 0.014419
LRRTM1 leucine rich repeat transmembrane neuronal 1 0.014195
PTPDC1 protein tyrosine phosphatase domain containing 1 0.014095
TMEM41B transmembrane protein 41B 0.013772
IFT81 intraflagellar transport 81 0.013624
SFTPC surfactant protein C 0.011649
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.011575
TTL tubulin tyrosine ligase 0.010202
PPP4C protein phosphatase 4, catalytic subunit 0.010179
TCL1A T-cell leukemia/lymphoma 1A 0.009256
DEPDC7 DEP domain containing 7 0.008868
POLD1 polymerase (DNA directed), delta 1, catalytic subunit 0.008724
ITGA9 integrin, alpha 9 0.008554
OR5P3 olfactory receptor, family 5, subfamily P, member 3 0.008071
PCDH20 protocadherin 20 0.007323
COX5A cytochrome c oxidase subunit Va 0.00706
MGA MGA, MAX dimerization protein 0.006009
GIMAP7 GTPase, IMAP family member 7 0.005937
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) 0.005317
FOXD3 forkhead box D3 0.00418
HEPACAM hepatic and glial cell adhesion molecule 0.003992
TMEM40 transmembrane protein 40 0.003874
TAL2 T-cell acute lymphocytic leukemia 2 0.002675
ACSS2 acyl-CoA synthetase short-chain family member 2 0.001368
CDK16 cyclin-dependent kinase 16 7.65E-4
ICK intestinal cell (MAK-like) kinase 6.03E-4
AKT3 v-akt murine thymoma viral oncogene homolog 3 5.79E-4

decreased expression

Symbol Name Standardized Value
ENC1 ectodermal-neural cortex 1 (with BTB domain) -1.2221
CRYAB crystallin, alpha B -1.22123
KRT8 keratin 8, type II -1.2196
PON3 paraoxonase 3 -1.21903
NISCH nischarin -1.21854
SIDT2 SID1 transmembrane family, member 2 -1.21781
KLF6 Kruppel-like factor 6 -1.21765
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 -1.21547
ZWINT ZW10 interacting kinetochore protein -1.2137
GLIS2 GLIS family zinc finger 2 -1.21178
LGALS1 lectin, galactoside-binding, soluble, 1 -1.20915
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17 -1.20915
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase -1.20883
DARS2 aspartyl-tRNA synthetase 2, mitochondrial -1.20653
DPYSL2 dihydropyrimidinase-like 2 -1.20638
MKNK2 MAP kinase interacting serine/threonine kinase 2 -1.20378
CREB3 cAMP responsive element binding protein 3 -1.20378
IGFBP4 insulin-like growth factor binding protein 4 -1.20378
ACTA2 actin, alpha 2, smooth muscle, aorta -1.2015
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 -1.19901
IAH1 isoamyl acetate-hydrolyzing esterase 1 homolog (S. cerevisiae) -1.19518
LPP LIM domain containing preferred translocation partner in lipoma -1.18857
ALG10B ALG10B, alpha-1,2-glucosyltransferase -1.18825
TRIM37 tripartite motif containing 37 -1.18568
GTF2I general transcription factor IIi -1.18313
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin) -1.18022
BFAR bifunctional apoptosis regulator -1.17777
TBCA tubulin folding cofactor A -1.17691
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) -1.1766
FAXC failed axon connections homolog (Drosophila) -1.17488
FLNA filamin A, alpha -1.17122
DEGS1 delta(4)-desaturase, sphingolipid 1 -1.16446
STEAP1 six transmembrane epithelial antigen of the prostate 1 -1.16301
NCS1 neuronal calcium sensor 1 -1.15595
CSF1 colony stimulating factor 1 (macrophage) -1.14878
MPZL1 myelin protein zero-like 1 -1.14863
CTNND1 catenin (cadherin-associated protein), delta 1 -1.1478
CSNK1A1 casein kinase 1, alpha 1 -1.14295
VCL vinculin -1.14043
ACTN1 actinin, alpha 1 -1.13921
PJA2 praja ring finger 2, E3 ubiquitin protein ligase -1.13754
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 -1.13077
ZMIZ1 zinc finger, MIZ-type containing 1 -1.13047
UBC ubiquitin C -1.12846
COL7A1 collagen, type VII, alpha 1 -1.12654
HMGA2 high mobility group AT-hook 2 -1.12075
FZD2 frizzled class receptor 2 -1.1206
MYL9 myosin, light chain 9, regulatory -1.11866
CPEB2 cytoplasmic polyadenylation element binding protein 2 -1.11829
KIFAP3 kinesin-associated protein 3 -1.11747
RBMS1 RNA binding motif, single stranded interacting protein 1 -1.11377
RRAS2 related RAS viral (r-ras) oncogene homolog 2 -1.1115
FKBP10 FK506 binding protein 10, 65 kDa -1.11055
TSKU tsukushi, small leucine rich proteoglycan -1.10952
PRNP prion protein -1.10909
LASP1 LIM and SH3 protein 1 -1.10763
CYR61 cysteine-rich, angiogenic inducer, 61 -1.10304
THBS1 thrombospondin 1 -1.10179
CLDN7 claudin 7 -1.09923
DBN1 drebrin 1 -1.09901
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2 -1.09602
FAM107B family with sequence similarity 107, member B -1.09552
LHFP lipoma HMGIC fusion partner -1.09364
MAP6 microtubule-associated protein 6 -1.09328
GLIPR2 GLI pathogenesis-related 2 -1.09077
CTTNBP2NL CTTNBP2 N-terminal like -1.08728
OSTC oligosaccharyltransferase complex subunit (non-catalytic) -1.08569
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -1.08547
SOX11 SRY (sex determining region Y)-box 11 -1.08029
GOLIM4 golgi integral membrane protein 4 -1.07979
RHNO1 RAD9-HUS1-RAD1 interacting nuclear orphan 1 -1.07836
STON1 stonin 1 -1.07573
TAGLN transgelin -1.07354
FKBP1A FK506 binding protein 1A, 12kDa -1.0717
ANXA1 annexin A1 -1.07106
MANF mesencephalic astrocyte-derived neurotrophic factor -1.07091
SFN stratifin -1.0636
FYTTD1 forty-two-three domain containing 1 -1.06339
RGS12 regulator of G-protein signaling 12 -1.06339
GPRC5A G protein-coupled receptor, class C, group 5, member A -1.06002
SH3PXD2A SH3 and PX domains 2A -1.05696
PLEKHA8 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8 -1.05453
KRTAP3-2 keratin associated protein 3-2 -1.04942
SSR1 signal sequence receptor, alpha -1.04851
BCL2L11 BCL2-like 11 (apoptosis facilitator) -1.04775
PHC2 polyhomeotic homolog 2 (Drosophila) -1.0465
GNG2 guanine nucleotide binding protein (G protein), gamma 2 -1.04637
TMEM184C transmembrane protein 184C -1.04409
AXL AXL receptor tyrosine kinase -1.04347
CAB39 calcium binding protein 39 -1.04121
ACTR3 ARP3 actin-related protein 3 homolog (yeast) -1.03917
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -1.03842
TPM1 tropomyosin 1 (alpha) -1.03842
TPM2 tropomyosin 2 (beta) -1.03767
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -1.03629
MDK midkine (neurite growth-promoting factor 2) -1.02877
VASH2 vasohibin 2 -1.02017
SEL1L sel-1 suppressor of lin-12-like (C. elegans) -1.0199
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -1.01828
GPR153 G protein-coupled receptor 153 -1.01808
TIMP2 TIMP metallopeptidase inhibitor 2 -1.01606
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1 -1.01007
RAMP2 receptor (G protein-coupled) activity modifying protein 2 -1.00935
ARPP19 cAMP-regulated phosphoprotein, 19kDa -1.00685
YAF2 YY1 associated factor 2 -1.00164
KANSL1 KAT8 regulatory NSL complex subunit 1 -0.999465
PKP2 plakophilin 2 -0.984358
STT3B STT3B, subunit of the oligosaccharyltransferase complex (catalytic) -0.976627
PPP1R14B protein phosphatase 1, regulatory (inhibitor) subunit 14B -0.975488
PMP22 peripheral myelin protein 22 -0.97492
VGLL3 vestigial-like family member 3 -0.973535
TRIM35 tripartite motif containing 35 -0.960582
CCDC47 coiled-coil domain containing 47 -0.960148
MARCKS myristoylated alanine-rich protein kinase C substrate -0.959777
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A -0.959591
COL11A1 collagen, type XI, alpha 1 -0.954565
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 -0.953884
ANXA3 annexin A3 -0.95308
RTN3 reticulon 3 -0.952771
FLNB filamin B, beta -0.952401
NRIP1 nuclear receptor interacting protein 1 -0.94902
TCF12 transcription factor 12 -0.947675
GSN gelsolin -0.94737
FAM71E1 family with sequence similarity 71, member E1 -0.946031
TMEM248 transmembrane protein 248 -0.935003
TMEM55A transmembrane protein 55A -0.932368
CACUL1 CDK2-associated, cullin domain 1 -0.93195
WIPI1 WD repeat domain, phosphoinositide interacting 1 -0.931831
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) -0.9288
HAPLN1 hyaluronan and proteoglycan link protein 1 -0.928326
KRT18 keratin 18, type I -0.926598
MEG8 maternally expressed 8 (non-protein coding) -0.925169
IKBIP IKBKB interacting protein -0.924872
ATG4C autophagy related 4C, cysteine peptidase -0.916866
SURF4 surfeit 4 -0.916341
SH3BGRL SH3 domain binding glutamate-rich protein like -0.915468
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1 -0.913145
FUBP1 far upstream element (FUSE) binding protein 1 -0.910987
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 -0.910987
CLASP1 cytoplasmic linker associated protein 1 -0.91058
NCAN neurocan -0.910347
SSU72 SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) -0.906011
CCND1 cyclin D1 -0.904403
RAB10 RAB10, member RAS oncogene family -0.903773
CSRP1 cysteine and glycine-rich protein 1 -0.903144
F3 coagulation factor III (thromboplastin, tissue factor) -0.901888
ADD1 adducin 1 (alpha) -0.900352
ABHD2 abhydrolase domain containing 2 -0.899102
PLK2 polo-like kinase 2 -0.892347
HERC2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 -0.891728
PTRF polymerase I and transcript release factor -0.886695
CD300LD CD300 molecule-like family member d -0.886695
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 -0.886084
PDLIM7 PDZ and LIM domain 7 (enigma) -0.883407
MARCKSL1 MARCKS-like 1 -0.879471
BRD7 bromodomain containing 7 -0.875241
PAWR PRKC, apoptosis, WT1, regulator -0.873114
CPD carboxypeptidase D -0.872136
OLA1 Obg-like ATPase 1 -0.870608
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 -0.870008
FHL1 four and a half LIM domains 1 -0.866915
HDLBP high density lipoprotein binding protein -0.866537
PCDHAC2 protocadherin alpha subfamily C, 2 -0.866428
SUZ12 SUZ12 polycomb repressive complex 2 subunit -0.859356
HMGN1 high mobility group nucleosome binding domain 1 -0.859356
TSPAN9 tetraspanin 9 -0.85909
MYH10 myosin, heavy chain 10, non-muscle -0.858772
MYH9 myosin, heavy chain 9, non-muscle -0.856638
CDH2 cadherin 2, type 1, N-cadherin (neuronal) -0.855947
SUCO SUN domain containing ossification factor -0.854885
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.845655
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 -0.842688
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog -0.83974
BAG2 BCL2-associated athanogene 2 -0.839174
FAM160B2 family with sequence similarity 160, member B2 -0.839071
BHLHE23 basic helix-loop-helix family, member e23 -0.838608
CALD1 caldesmon 1 -0.837684
PCBP4 poly(rC) binding protein 4 -0.837376
TMX3 thioredoxin-related transmembrane protein 3 -0.832531
CLCF1 cardiotrophin-like cytokine factor 1 -0.832327
MTMR2 myotubularin related protein 2 -0.828623
CAV1 caveolin 1, caveolae protein, 22kDa -0.828068
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.826406
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 -0.826104
RHOT2 ras homolog family member T2 -0.825201
TREM2 triggering receptor expressed on myeloid cells 2 -0.825101
MYO1C myosin IC -0.820712
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa -0.820712
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.816445
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) -0.815804
MSL3P1 male-specific lethal 3 homolog (Drosophila) pseudogene 1 -0.815459
EIF3C eukaryotic translation initiation factor 3, subunit C -0.814081
RBP1 retinol binding protein 1, cellular -0.813542
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2 -0.81266
CNPY2 canopy FGF signaling regulator 2 -0.812024
SHROOM2 shroom family member 2 -0.811926
INA internexin neuronal intermediate filament protein, alpha -0.811047
PRSS23 protease, serine, 23 -0.806042
OGFRL1 opioid growth factor receptor-like 1 -0.803242
IWS1 IWS1 homolog (S. cerevisiae) -0.803146
TIAL1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 -0.80094
MORC2 MORC family CW-type zinc finger 2 -0.799793
FOSL2 FOS-like antigen 2 -0.797983
TMEM132A transmembrane protein 132A -0.796748
SERINC1 serine incorporator 1 -0.796748
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) -0.795182
VIM vimentin -0.794377
DUSP14 dual specificity phosphatase 14 -0.793196
PERP PERP, TP53 apoptosis effector -0.783072
HSPB8 heat shock 22kDa protein 8 -0.781319
TUBB6 tubulin, beta 6 class V -0.780905
KIAA1109 KIAA1109 -0.780215
COL1A1 collagen, type I, alpha 1 -0.777698
XPO7 exportin 7 -0.774786
CLU clusterin -0.773698
KCTD3 potassium channel tetramerization domain containing 3 -0.770537
BTG2 BTG family, member 2 -0.76874
MAP4K5 mitogen-activated protein kinase kinase kinase kinase 5 -0.767086
RC3H1 ring finger and CCCH-type domains 1 -0.766595
NR6A1 nuclear receptor subfamily 6, group A, member 1 -0.763927
CNIH4 cornichon family AMPA receptor auxiliary protein 4 -0.76375
MAPRE2 microtubule-associated protein, RP/EB family, member 2 -0.759205
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) -0.758723
BCL2L1 BCL2-like 1 -0.757365
PARD6B par-6 family cell polarity regulator beta -0.757365
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae) -0.756666
ARF4 ADP-ribosylation factor 4 -0.756579
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) -0.75562
SLC51B solute carrier family 51, beta subunit -0.75488
CNN2 calponin 2 -0.753708
RCAN2 regulator of calcineurin 2 -0.752496
PTCD3 pentatricopeptide repeat domain 3 -0.751416
SERTAD4 SERTA domain containing 4 -0.747164
ACSL4 acyl-CoA synthetase long-chain family member 4 -0.745415
CMTM3 CKLF-like MARVEL transmembrane domain containing 3 -0.745287
LIMD2 LIM domain containing 2 -0.738154
RNPC3 RNA-binding region (RNP1, RRM) containing 3 -0.737234
KPNA4 karyopherin alpha 4 (importin alpha 3) -0.736315
FAM90A1 family with sequence similarity 90, member A1 -0.733489
CAV2 caveolin 2 -0.728302
SLC39A10 solute carrier family 39 (zinc transporter), member 10 -0.726873
RRP1 ribosomal RNA processing 1 -0.722773
SH3GLB1 SH3-domain GRB2-like endophilin B1 -0.720397
UPK3A uroplakin 3A -0.71668
PROSC proline synthetase co-transcribed homolog (bacterial) -0.716243
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) -0.716163
HNF1B HNF1 homeobox B -0.716084
CHN1 chimerin 1 -0.716004
STMN2 stathmin 2 -0.715805
KIAA1919 KIAA1919 -0.714259
GBP2 guanylate binding protein 2, interferon-inducible -0.713389
ACTA1 actin, alpha 1, skeletal muscle -0.711734
NME1 NME/NM23 nucleoside diphosphate kinase 1 -0.707589
WBP5 WW domain binding protein 5 -0.706928
UBE2B ubiquitin-conjugating enzyme E2B -0.706423
RHOB ras homolog family member B -0.704178
RND3 Rho family GTPase 3 -0.703098
AMOTL1 angiomotin like 1 -0.703021
TP53BP1 tumor protein p53 binding protein 1 -0.701408
ABLIM1 actin binding LIM protein 1 -0.701064
BAZ1A bromodomain adjacent to zinc finger domain, 1A -0.698622
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 -0.697369
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) -0.696384
HS6ST2 heparan sulfate 6-O-sulfotransferase 2 -0.694156
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 -0.693893
ARL4C ADP-ribosylation factor-like 4C -0.693742
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase -0.693066
PLXNC1 plexin C1 -0.692317
RAB34 RAB34, member RAS oncogene family -0.692242
TMEM2 transmembrane protein 2 -0.691084
PTEN phosphatase and tensin homolog -0.6906
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.689372
ARSB arylsulfatase B -0.683689
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein -0.682959
AMMECR1L AMMECR1-like -0.682011
DUSP4 dual specificity phosphatase 4 -0.68161
TPM4 tropomyosin 4 -0.680738
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -0.678493
GBP1 guanylate binding protein 1, interferon-inducible -0.67723
SYNPO2L synaptopodin 2-like -0.676978
PCDH7 protocadherin 7 -0.673115
FAM46B family with sequence similarity 46, member B -0.672262
RHOH ras homolog family member H -0.668869
S100A10 S100 calcium binding protein A10 -0.667779
ARF3 ADP-ribosylation factor 3 -0.664012
TMEM126A transmembrane protein 126A -0.663249
CD24 CD24 molecule -0.6628
ARSK arylsulfatase family, member K -0.661425
SCD5 stearoyl-CoA desaturase 5 -0.65893
WISP1 WNT1 inducible signaling pathway protein 1 -0.658779
RAP1B RAP1B, member of RAS oncogene family -0.658026
CALU calumenin -0.656007
PDPN podoplanin -0.655262
PLIN2 perilipin 2 -0.654518
RNF139 ring finger protein 139 -0.653701
GPC4 glypican 4 -0.651039
CD44 CD44 molecule (Indian blood group) -0.650965
ST14 suppression of tumorigenicity 14 (colon carcinoma) -0.649059
TMEM47 transmembrane protein 47 -0.647527
EPHA3 EPH receptor A3 -0.647382
ABRACL ABRA C-terminal like -0.646292
PLAUR plasminogen activator, urokinase receptor -0.646002
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 -0.645929
MSN moesin -0.644481
UBE3C ubiquitin protein ligase E3C -0.644337
TMEM38B transmembrane protein 38B -0.643326
SETD7 SET domain containing (lysine methyltransferase) 7 -0.638397
HYOU1 hypoxia up-regulated 1 -0.635221
MYADM myeloid-associated differentiation marker -0.634729
PCNXL4 pecanex-like 4 (Drosophila) -0.634447
RPL13 ribosomal protein L13 -0.634096
PIEZO1 piezo-type mechanosensitive ion channel component 1 -0.633047
TNFRSF19 tumor necrosis factor receptor superfamily, member 19 -0.632769
SDC1 syndecan 1 -0.630132
AMPD2 adenosine monophosphate deaminase 2 -0.624643
TRIM3 tripartite motif containing 3 -0.624236
MIDN midnolin -0.621396
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 -0.615061
SEPW1 selenoprotein W, 1 -0.614468
FGF21 fibroblast growth factor 21 -0.613417
RCN2 reticulocalbin 2, EF-hand calcium binding domain -0.613286
UBP1 upstream binding protein 1 (LBP-1a) -0.612958
GATAD1 GATA zinc finger domain containing 1 -0.609306
PITX2 paired-like homeodomain 2 -0.600559
DOCK11 dedicator of cytokinesis 11 -0.600496
SLC5A10 solute carrier family 5 (sodium/sugar cotransporter), member 10 -0.599553
SLC25A53 solute carrier family 25, member 53 -0.598925
TPR translocated promoter region, nuclear basket protein -0.598674
PIM1 Pim-1 proto-oncogene, serine/threonine kinase -0.596055
UBE2J1 ubiquitin-conjugating enzyme E2, J1 -0.595993
FAM174A family with sequence similarity 174, member A -0.594204
TGFB2 transforming growth factor, beta 2 -0.593712
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 -0.592974
NXN nucleoredoxin -0.591871
TEAD2 TEA domain family member 2 -0.589918
CPNE2 copine II -0.588831
BCAM basal cell adhesion molecule (Lutheran blood group) -0.58871
ELOVL1 ELOVL fatty acid elongase 1 -0.588047
APP amyloid beta (A4) precursor protein -0.586004
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2 -0.585645
STPG1 sperm-tail PG-rich repeat containing 1 -0.585585
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 -0.582429
CUL1 cullin 1 -0.582193
MOB3A MOB kinase activator 3A -0.582075
SLITRK5 SLIT and NTRK-like family, member 5 -0.581781
EXOC4 exocyst complex component 4 -0.578323
AHCY adenosylhomocysteinase -0.575999
PON2 paraoxonase 2 -0.574447
TMSB4X thymosin beta 4, X-linked -0.573988
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) -0.573472
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) -0.573072
AIF1L allograft inflammatory factor 1-like -0.572957
RNF128 ring finger protein 128, E3 ubiquitin protein ligase -0.572329
HPCAL1 hippocalcin-like 1 -0.567585
SOX4 SRY (sex determining region Y)-box 4 -0.567529
SSBP3 single stranded DNA binding protein 3 -0.567473
PAX6 paired box 6 -0.56669
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -0.566355
SFTPA1 surfactant protein A1 -0.564017
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -0.563357
QSOX1 quiescin Q6 sulfhydryl oxidase 1 -0.562534
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 -0.56237
RIPK4 receptor-interacting serine-threonine kinase 4 -0.561986
FRMD4B FERM domain containing 4B -0.560186
STX12 syntaxin 12 -0.560023
UBE2E3 ubiquitin-conjugating enzyme E2E 3 -0.55975
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent) -0.55975
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.559043
SHFM1 split hand/foot malformation (ectrodactyly) type 1 -0.5585
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase -0.558282
CNOT7 CCR4-NOT transcription complex, subunit 7 -0.557098
DUSP1 dual specificity phosphatase 1 -0.55246
NRG3 neuregulin 3 -0.550886
HINFP histone H4 transcription factor -0.548227
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 -0.547967
EFNB2 ephrin-B2 -0.547448
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.547033
ARL5A ADP-ribosylation factor-like 5A -0.546515
GSTA2 glutathione S-transferase alpha 2 -0.54605
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.545386
FN1 fibronectin 1 -0.544977
RBPMS RNA binding protein with multiple splicing -0.543246
HSPA1B heat shock 70kDa protein 1B -0.543195
T T, brachyury homolog (mouse) -0.54203
CPNE8 copine VIII -0.541928
GAP43 growth associated protein 43 -0.541574
RTN4 reticulon 4 -0.540062
ARHGAP23 Rho GTPase activating protein 23 -0.539264
WNK1 WNK lysine deficient protein kinase 1 -0.539065
GNPDA2 glucosamine-6-phosphate deaminase 2 -0.535989
PRPF39 pre-mRNA processing factor 39 -0.5333
CHTF8 CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae) -0.533203
RWDD4 RWD domain containing 4 -0.533058
SPAG9 sperm associated antigen 9 -0.531749
PBX3 pre-B-cell leukemia homeobox 3 -0.530493
MSL3 male-specific lethal 3 homolog (Drosophila) -0.529963
MAGEA6 melanoma antigen family A6 -0.529867
EPDR1 ependymin related 1 -0.528247
NEO1 neogenin 1 -0.5273
RBM27 RNA binding motif protein 27 -0.527016
ACVR2A activin A receptor, type IIA -0.526449
KLF7 Kruppel-like factor 7 (ubiquitous) -0.525883
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein -0.52532
CAPN2 calpain 2, (m/II) large subunit -0.52499
AMOTL2 angiomotin like 2 -0.524567
EPN2 epsin 2 -0.523635
CNEP1R1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 -0.521556
KLHDC2 kelch domain containing 2 -0.520635
MCL1 myeloid cell leukemia 1 -0.518983
MTX2 metaxin 2 -0.518847
RAB2A RAB2A, member RAS oncogene family -0.517989
MEG3 maternally expressed 3 (non-protein coding) -0.517899
NREP neuronal regeneration related protein -0.517
KIAA0100 KIAA0100 -0.516415
NEFL neurofilament, light polypeptide -0.515471
KLF3 Kruppel-like factor 3 (basic) -0.515113
GLS glutaminase -0.514172
COPA coatomer protein complex, subunit alpha -0.513686
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 -0.512893
SNAPC3 small nuclear RNA activating complex, polypeptide 3, 50kDa -0.512366
AP2A2 adaptor-related protein complex 2, alpha 2 subunit -0.5114
BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 -0.508571
PALLD palladin, cytoskeletal associated protein -0.506857
TSPAN18 tetraspanin 18 -0.506729
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.5066
PPP4R2 protein phosphatase 4, regulatory subunit 2 -0.5066
CCDC127 coiled-coil domain containing 127 -0.505277
TMEM33 transmembrane protein 33 -0.504049
PPP6R3 protein phosphatase 6, regulatory subunit 3 -0.503965
PRKCI protein kinase C, iota -0.501754
NPNT nephronectin -0.500922
PPP1R18 protein phosphatase 1, regulatory subunit 18 -0.499108
SEPT11 septin 11 -0.49866
SRI sorcin -0.496588
S100A6 S100 calcium binding protein A6 -0.496264
TRIM59 tripartite motif containing 59 -0.49586
EPHA1 EPH receptor A1 -0.49454
ANLN anillin, actin binding protein -0.494381
ITGAV integrin, alpha V -0.494064
WWTR1 WW domain containing transcription regulator 1 -0.493866
INSIG2 insulin induced gene 2 -0.493708
C8ORF82 chromosome 8 open reading frame 82 -0.493549
RABGAP1L RAB GTPase activating protein 1-like -0.493312
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 -0.492877
ARF6 ADP-ribosylation factor 6 -0.492521
GRK6 G protein-coupled receptor kinase 6 -0.492482
MRS2 MRS2 magnesium transporter -0.491417
LPGAT1 lysophosphatidylglycerol acyltransferase 1 -0.491141
PICALM phosphatidylinositol binding clathrin assembly protein -0.490478
MIER1 mesoderm induction early response 1, transcriptional regulator -0.487322
ATXN7L1 ataxin 7-like 1 -0.487054
STEAP2 STEAP family member 2, metalloreductase -0.486862
F7 coagulation factor VII (serum prothrombin conversion accelerator) -0.486479
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3 -0.484827
LOC100505478 uncharacterized LOC100505478 -0.484489
PFN2 profilin 2 -0.484003
FAM13C family with sequence similarity 13, member C -0.48333
GNG3 guanine nucleotide binding protein (G protein), gamma 3 -0.482956
DAPK3 death-associated protein kinase 3 -0.482434
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15 -0.482286
GLI3 GLI family zinc finger 3 -0.480207
VAMP3 vesicle-associated membrane protein 3 -0.479079
CKS1B CDC28 protein kinase regulatory subunit 1B -0.478138
NGEF neuronal guanine nucleotide exchange factor -0.478102
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 -0.477285
CFL1 cofilin 1 (non-muscle) -0.476611
EIF3J eukaryotic translation initiation factor 3, subunit J -0.476045
ANKRD17 ankyrin repeat domain 17 -0.475762
UBE2E2 ubiquitin-conjugating enzyme E2E 2 -0.475691
ZNF354C zinc finger protein 354C -0.473521
UTRN utrophin -0.472935
RIN1 Ras and Rab interactor 1 -0.471628
LPAR4 lysophosphatidic acid receptor 4 -0.47125
FAM120AOS family with sequence similarity 120A opposite strand -0.471216
GNAQ guanine nucleotide binding protein (G protein), q polypeptide -0.470026
ZFPM2 zinc finger protein, FOG family member 2 -0.469858
GNAS GNAS complex locus -0.469691
ACTC1 actin, alpha, cardiac muscle 1 -0.46909
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.468287
VAT1 vesicle amine transport 1 -0.46772
CNN1 calponin 1, basic, smooth muscle -0.466493
ANXA8 annexin A8 -0.466298
PARVA parvin, alpha -0.465226
MSI2 musashi RNA-binding protein 2 -0.463349
RAB12 RAB12, member RAS oncogene family -0.462649
TCEAL8 transcription elongation factor A (SII)-like 8 -0.459912
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 -0.459416
AXIN2 axin 2 -0.459324
PHF14 PHD finger protein 14 -0.457676
MGST3 microsomal glutathione S-transferase 3 -0.456976
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 -0.456276
CD109 CD109 molecule -0.456215
LITAF lipopolysaccharide-induced TNF factor -0.4558
EML1 echinoderm microtubule associated protein like 1 -0.455297
PRPS2 phosphoribosyl pyrophosphate synthetase 2 -0.453731
CCT3 chaperonin containing TCP1, subunit 3 (gamma) -0.452764
NUAK1 NUAK family, SNF1-like kinase, 1 -0.45219
BLOC1S5 biogenesis of lysosomal organelles complex-1, subunit 5, muted -0.451246
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4 -0.451131
TMSB10 thymosin beta 10 -0.45096
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.450731
IER3 immediate early response 3 -0.450474
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 -0.446554
TBCD tubulin folding cofactor D -0.446339
TSPAN6 tetraspanin 6 -0.445535
RBCK1 RanBP-type and C3HC4-type zinc finger containing 1 -0.445428
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.444198
FEM1C fem-1 homolog c (C. elegans) -0.444092
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 -0.443329
KPNA3 karyopherin alpha 3 (importin alpha 4) -0.442992
NOTCH3 notch 3 -0.441184
CAPN10 calpain 10 -0.440521
SNX6 sorting nexin 6 -0.439572
CAGE1 cancer antigen 1 -0.439123
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 -0.438875
C9ORF91 chromosome 9 open reading frame 91 -0.438004
NT5DC2 5'-nucleotidase domain containing 2 -0.437859
BBX bobby sox homolog (Drosophila) -0.437834
FIGLA folliculogenesis specific basic helix-loop-helix -0.437184
ECHDC3 enoyl CoA hydratase domain containing 3 -0.436414
DLAT dihydrolipoamide S-acetyltransferase -0.436342
MXRA8 matrix-remodelling associated 8 -0.435146
SAMD4A sterile alpha motif domain containing 4A -0.435146
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric -0.4351
LIMS1 LIM and senescent cell antigen-like domains 1 -0.434428
KLHL9 kelch-like family member 9 -0.433316
CAPZB capping protein (actin filament) muscle Z-line, beta -0.433316
DNAJC18 DnaJ (Hsp40) homolog, subfamily C, member 18 -0.43327
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1 -0.433223
CCNG1 cyclin G1 -0.431151
PLAC8 placenta-specific 8 -0.430884
ZADH2 zinc binding alcohol dehydrogenase domain containing 2 -0.430662
RORA RAR-related orphan receptor A -0.430239
ZNF319 zinc finger protein 319 -0.429185
CDC25A cell division cycle 25A -0.429142
AHNAK AHNAK nucleoprotein -0.429035
EPB41L3 erythrocyte membrane protein band 4.1-like 3 -0.428563
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) -0.428177
CD151 CD151 molecule (Raph blood group) -0.427194
SAP18 Sin3A-associated protein, 18kDa -0.426782
CHD4 chromodomain helicase DNA binding protein 4 -0.426576
FNDC3B fibronectin type III domain containing 3B -0.425917
ISX intestine-specific homeobox -0.425608
ZFAND5 zinc finger, AN1-type domain 5 -0.425307
NCKAP5L NCK-associated protein 5-like -0.425089
CD276 CD276 molecule -0.424415
MAST2 microtubule associated serine/threonine kinase 2 -0.42394
FARSA phenylalanyl-tRNA synthetase, alpha subunit -0.423487
GAS2L1 growth arrest-specific 2 like 1 -0.423252
PDLIM5 PDZ and LIM domain 5 -0.423195
SHISA4 shisa family member 4 -0.423138
THSD4 thrombospondin, type I, domain containing 4 -0.071013
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant -0.071013
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 -0.070813
CENPM centromere protein M -0.070115
SORD sorbitol dehydrogenase -0.070098
RNF17 ring finger protein 17 -0.069613
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.068102
PKLR pyruvate kinase, liver and RBC -0.067933
TMEM262 transmembrane protein 262 -0.067415
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -0.067122
SMIM20 small integral membrane protein 20 -0.066931
WRAP73 WD repeat containing, antisense to TP73 -0.065946
MCM10 minichromosome maintenance complex component 10 -0.064678
CCND3 cyclin D3 -0.064573
SIVA1 SIVA1, apoptosis-inducing factor -0.063814
TUBA4A tubulin, alpha 4a -0.063418
SMAD6 SMAD family member 6 -0.062845
GLTSCR2 glioma tumor suppressor candidate region gene 2 -0.062595
POLR1B polymerase (RNA) I polypeptide B, 128kDa -0.062397
FTH1 ferritin, heavy polypeptide 1 -0.062148
KIF21B kinesin family member 21B -0.061658
TMEM8C transmembrane protein 8C -0.061402
CHURC1 churchill domain containing 1 -0.0604
CFP complement factor properdin -0.059779
CENPV centromere protein V -0.058241
TEX2 testis expressed 2 -0.057796
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 -0.056948
NAP1L1 nucleosome assembly protein 1-like 1 -0.05693
ADM adrenomedullin -0.056628
ATAD5 ATPase family, AAA domain containing 5 -0.056553
ADAM15 ADAM metallopeptidase domain 15 -0.056365
TMEM25 transmembrane protein 25 -0.055858
VEGFB vascular endothelial growth factor B -0.055763
FGFR4 fibroblast growth factor receptor 4 -0.055515
TMEM236 transmembrane protein 236 -0.055113
IMPDH2 IMP (inosine 5'-monophosphate) dehydrogenase 2 -0.054368
RPL29 ribosomal protein L29 -0.054235
KNSTRN kinetochore-localized astrin/SPAG5 binding protein -0.054215
FGD4 FYVE, RhoGEF and PH domain containing 4 -0.053814
UBE2S ubiquitin-conjugating enzyme E2S -0.053061
OGT O-linked N-acetylglucosamine (GlcNAc) transferase -0.052983
ZNF710 zinc finger protein 710 -0.05277
PDZD2 PDZ domain containing 2 -0.052615
RPS21 ribosomal protein S21 -0.051763
TYRO3 TYRO3 protein tyrosine kinase -0.051685
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 -0.051588
PLA2G1B phospholipase A2, group IB (pancreas) -0.050784
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.050686
VRK1 vaccinia related kinase 1 -0.05043
PSMC3IP PSMC3 interacting protein -0.04935
LRP1 low density lipoprotein receptor-related protein 1 -0.048614
NOP10 NOP10 ribonucleoprotein -0.048016
RNF40 ring finger protein 40, E3 ubiquitin protein ligase -0.047897
NDUFA11 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa -0.047419
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 -0.046699
MOV10 Mov10 RISC complex RNA helicase -0.046233
SAMM50 SAMM50 sorting and assembly machinery component -0.046052
DBX1 developing brain homeobox 1 -0.045286
ZFP57 ZFP57 zinc finger protein -0.044272
ZBTB21 zinc finger and BTB domain containing 21 -0.044109
ZNF658 zinc finger protein 658 -0.043393
CSRNP2 cysteine-serine-rich nuclear protein 2 -0.043373
ZDHHC17 zinc finger, DHHC-type containing 17 -0.043169
SLC35A4 solute carrier family 35, member A4 -0.04268
RWDD2B RWD domain containing 2B -0.042394
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) -0.041857
ICAM1 intercellular adhesion molecule 1 -0.041443
NLGN1 neuroligin 1 -0.041175
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa -0.040721
FSD2 fibronectin type III and SPRY domain containing 2 -0.040638
NPVF neuropeptide VF precursor -0.040535
CDT1 chromatin licensing and DNA replication factor 1 -0.040453
HCK HCK proto-oncogene, Src family tyrosine kinase -0.039307
ENO4 enolase family member 4 -0.039286
SRP19 signal recognition particle 19kDa -0.03839
HLA-A major histocompatibility complex, class I, A -0.038077
TALDO1 transaldolase 1 -0.037531
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) -0.037025
SF3A2 splicing factor 3a, subunit 2, 66kDa -0.036603
SLC7A3 solute carrier family 7 (cationic amino acid transporter, y+ system), member 3 -0.036371
SMC1A structural maintenance of chromosomes 1A -0.03595
TNIP1 TNFAIP3 interacting protein 1 -0.035677
OTX2 orthodenticle homeobox 2 -0.034677
CIB3 calcium and integrin binding family member 3 -0.034422
RPL15 ribosomal protein L15 -0.03147
MARC2 mitochondrial amidoxime reducing component 2 -0.031276
FOXRED1 FAD-dependent oxidoreductase domain containing 1 -0.030003
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) -0.029982
BMPER BMP binding endothelial regulator -0.029158
KIF5A kinesin family member 5A -0.02879
CTU2 cytosolic thiouridylase subunit 2 homolog (S. pombe) -0.028272
ATR ATR serine/threonine kinase -0.028098
MAEL maelstrom spermatogenic transposon silencer -0.028054
RBM6 RNA binding motif protein 6 -0.027441
PIKFYVE phosphoinositide kinase, FYVE finger containing -0.026263
CASP9 caspase 9, apoptosis-related cysteine peptidase -0.02611
FADS3 fatty acid desaturase 3 -0.025077
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -0.024461
FAM159B family with sequence similarity 159, member B -0.024241
TRIM24 tripartite motif containing 24 -0.023385
TNS3 tensin 3 -0.022233
DSCC1 DNA replication and sister chromatid cohesion 1 -0.021745
FGF12 fibroblast growth factor 12 -0.021369
EFCAB1 EF-hand calcium binding domain 1 -0.021059
WNT8B wingless-type MMTV integration site family, member 8B -0.020971
TDO2 tryptophan 2,3-dioxygenase -0.020905
SLC22A2 solute carrier family 22 (organic cation transporter), member 2 -0.020057
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase -0.019945
TAOK2 TAO kinase 2 -0.019878
WFDC2 WAP four-disulfide core domain 2 -0.019745
UBR5 ubiquitin protein ligase E3 component n-recognin 5 -0.019321
PRDM14 PR domain containing 14 -0.019209
KALRN kalirin, RhoGEF kinase -0.019099
NLGN3 neuroligin 3 -0.019076
RAB27A RAB27A, member RAS oncogene family -0.017713
UTF1 undifferentiated embryonic cell transcription factor 1 -0.016905
LMO3 LIM domain only 3 (rhombotin-like 2) -0.016099
AKAP11 A kinase (PRKA) anchor protein 11 -0.014882
TMLHE trimethyllysine hydroxylase, epsilon -0.014723
C1QL3 complement component 1, q subcomponent-like 3 -0.014205
GJB3 gap junction protein, beta 3, 31kDa -0.012555
MTFR1L mitochondrial fission regulator 1-like -0.01217
CDC23 cell division cycle 23 -0.010767
DNAI1 dynein, axonemal, intermediate chain 1 -0.010744
SARS seryl-tRNA synthetase -0.009809
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast) -0.009695
ABHD11 abhydrolase domain containing 11 -0.009604
ZNF274 zinc finger protein 274 -0.008944
RERE arginine-glutamic acid dipeptide (RE) repeats -0.008126
TRIM25 tripartite motif containing 25 -0.00808
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 -0.008034
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 -0.007782
MED13L mediator complex subunit 13-like -0.006364
COBL cordon-bleu WH2 repeat protein -0.00625
DPPA4 developmental pluripotency associated 4 -0.006227
TBX4 T-box 4 -0.005931
PHACTR2 phosphatase and actin regulator 2 -0.005816
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1 -0.005473
RAE1 ribonucleic acid export 1 -0.004944
STAMBPL1 STAM binding protein-like 1 -0.004715
PRRC1 proline-rich coiled-coil 1 -0.003247
ZNF260 zinc finger protein 260 -0.001359
RPL36 ribosomal protein L36 -0.001336
MAST4 microtubule associated serine/threonine kinase family member 4 -0.001336
PNLIP pancreatic lipase -0.001083
OSBPL2 oxysterol binding protein-like 2 -5.77E-4
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -1.38E-4
Funding