synapse Gene Set

Dataset SynGO Synaptic Gene Annotations
Category structural or functional annotations
Type biological term
Description The junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell; the site of interneuronal communication. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane. (Gene Ontology, GO_0045202)
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Genes

291 genes associated with the synaptic term synapse from the SynGO Synaptic Gene Annotations dataset.

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ACTBL2 actin, beta-like 2
ACTC1 actin, alpha, cardiac muscle 1
ACTN1 actinin, alpha 1
ADD1 adducin 1 (alpha)
ADGRB2 adhesion G protein-coupled receptor B2
ADORA2B adenosine A2b receptor
ADORA3 adenosine A3 receptor
AGRN agrin
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase)
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
AP1M1 adaptor-related protein complex 1, mu 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
APOA4 apolipoprotein A-IV
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa
ARPC5L actin related protein 2/3 complex, subunit 5-like
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATG5 autophagy related 5
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
AXIN1 axin 1
BCAS1 breast carcinoma amplified sequence 1
BIN1 bridging integrator 1
BRINP1 bone morphogenetic protein/retinoic acid inducible neural-specific 1
CALB2 calbindin 2
CAPRIN1 cell cycle associated protein 1
CC2D1A coiled-coil and C2 domain containing 1A
CDH10 cadherin 10, type 2 (T2-cadherin)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDH13 cadherin 13
CDH23 cadherin-related 23
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDH9 cadherin 9, type 2 (T1-cadherin)
CLU clusterin
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CNTN1 contactin 1
CORIN corin, serine peptidase
CORO1A coronin, actin binding protein, 1A
CORO1B coronin, actin binding protein, 1B
CPNE4 copine IV
CPNE7 copine VII
CRELD1 cysteine-rich with EGF-like domains 1
CYFIP2 cytoplasmic FMR1 interacting protein 2
DAAM1 dishevelled associated activator of morphogenesis 1
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila)
DMTN dematin actin binding protein
DPP6 dipeptidyl-peptidase 6
DPYSL3 dihydropyrimidinase-like 3
DPYSL5 dihydropyrimidinase-like 5
DVL3 dishevelled segment polarity protein 3
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
EEF2 eukaryotic translation elongation factor 2
EIF1AX eukaryotic translation initiation factor 1A, X-linked
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EIF3B eukaryotic translation initiation factor 3, subunit B
EIF3D eukaryotic translation initiation factor 3, subunit D
EIF3F eukaryotic translation initiation factor 3, subunit F
EIF3I eukaryotic translation initiation factor 3, subunit I
EIF3L eukaryotic translation initiation factor 3, subunit L
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3
EIF5 eukaryotic translation initiation factor 5
EIF5A eukaryotic translation initiation factor 5A
EIF5B eukaryotic translation initiation factor 5B
EIF6 eukaryotic translation initiation factor 6
ELAVL2 ELAV like neuron-specific RNA binding protein 2
ELMOD1 ELMO/CED-12 domain containing 1
EPS15 epidermal growth factor receptor pathway substrate 15
ETFA electron-transfer-flavoprotein, alpha polypeptide
FAM171B family with sequence similarity 171, member B
FBXL20 F-box and leucine-rich repeat protein 20
FCHO2 FCH domain only 2
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGG fibrinogen gamma chain
FKBP1A FK506 binding protein 1A, 12kDa
FLOT1 flotillin 1
FLOT2 flotillin 2
FUBP1 far upstream element (FUSE) binding protein 1
FZD4 frizzled class receptor 4
FZD5 frizzled class receptor 5
GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3
GDI2 GDP dissociation inhibitor 2
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4
GNB5 guanine nucleotide binding protein (G protein), beta 5
GNG12 guanine nucleotide binding protein (G protein), gamma 12
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GNG2 guanine nucleotide binding protein (G protein), gamma 2
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPC1 glypican 1
GPC4 glypican 4
GPC6 glypican 6
GRN granulin
HABP4 hyaluronan binding protein 4
HAPLN1 hyaluronan and proteoglycan link protein 1
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HNRNPDL heterogeneous nuclear ribonucleoprotein D-like
HNRNPF heterogeneous nuclear ribonucleoprotein F
HNRNPL heterogeneous nuclear ribonucleoprotein L
HNRNPLL heterogeneous nuclear ribonucleoprotein L-like
HNRNPM heterogeneous nuclear ribonucleoprotein M
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2
IL1RAP interleukin 1 receptor accessory protein
LIN7A lin-7 homolog A (C. elegans)
LIN7C lin-7 homolog C (C. elegans)
LRRTM4 leucine rich repeat transmembrane neuronal 4
MAGI3 membrane associated guanylate kinase, WW and PDZ domain containing 3
MAP1LC3A microtubule-associated protein 1 light chain 3 alpha
MLF2 myeloid leukemia factor 2
MRPS12 mitochondrial ribosomal protein S12
MYLK myosin light chain kinase
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma
NCAN neurocan
NPTX2 neuronal pentraxin II
NRG3 neuregulin 3
NTN1 netrin 1
NUDT3 nudix (nucleoside diphosphate linked moiety X)-type motif 3
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1
NWD2 NACHT and WD repeat domain containing 2
NXPH4 neurexophilin 4
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
PABPC1 poly(A) binding protein, cytoplasmic 1
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PCDH8 protocadherin 8
PDE10A phosphodiesterase 10A
PGRMC2 progesterone receptor membrane component 2
PHB1 prohibitin 1
PLCXD3 phosphatidylinositol-specific phospholipase C, X domain containing 3
PLD1 phospholipase D1, phosphatidylcholine-specific
PLXNA1 plexin A1
PPA2 pyrophosphatase (inorganic) 2
PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
PURG purine-rich element binding protein G
QKI QKI, KH domain containing, RNA binding
RAB18 RAB18, member RAS oncogene family
RAB1B RAB1B, member RAS oncogene family
RAB21 RAB21, member RAS oncogene family
RAB8A RAB8A, member RAS oncogene family
RABAC1 Rab acceptor 1 (prenylated)
RANBP6 RAN binding protein 6
RAP2A RAP2A, member of RAS oncogene family
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RHEBP1 Ras-homolog enriched in brain pseudogene 1
RHOB ras homolog family member B
RIMS4 regulating synaptic membrane exocytosis 4
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RPL10 ribosomal protein L10
RPL10A ribosomal protein L10a
RPL11 ribosomal protein L11
RPL12 ribosomal protein L12
RPL13 ribosomal protein L13
RPL13A ribosomal protein L13a
RPL14 ribosomal protein L14
RPL15 ribosomal protein L15
RPL17 ribosomal protein L17
RPL18 ribosomal protein L18
RPL18A ribosomal protein L18a
RPL19 ribosomal protein L19
RPL21 ribosomal protein L21
RPL22 ribosomal protein L22
RPL23 ribosomal protein L23
RPL23A ribosomal protein L23a
RPL24 ribosomal protein L24
RPL26 ribosomal protein L26
RPL27 ribosomal protein L27
RPL27A ribosomal protein L27a
RPL28 ribosomal protein L28
RPL29 ribosomal protein L29
RPL3 ribosomal protein L3
RPL30 ribosomal protein L30
RPL31 ribosomal protein L31
RPL32 ribosomal protein L32
RPL34 ribosomal protein L34
RPL35 ribosomal protein L35
RPL35A ribosomal protein L35a
RPL36 ribosomal protein L36
RPL36AL ribosomal protein L36a-like
RPL37 ribosomal protein L37
RPL37A ribosomal protein L37a
RPL38 ribosomal protein L38
RPL5 ribosomal protein L5
RPL6 ribosomal protein L6
RPL7 ribosomal protein L7
RPL7AP10 ribosomal protein L7a pseudogene 10
RPL8 ribosomal protein L8
RPL9 ribosomal protein L9
RPLP0 ribosomal protein, large, P0
RPLP1 ribosomal protein, large, P1
RPLP2 ribosomal protein, large, P2
RPS10 ribosomal protein S10
RPS11 ribosomal protein S11
RPS13 ribosomal protein S13
RPS14 ribosomal protein S14
RPS15 ribosomal protein S15
RPS15A ribosomal protein S15a
RPS16 ribosomal protein S16
RPS17 ribosomal protein S17
RPS18 ribosomal protein S18
RPS19 ribosomal protein S19
RPS2 ribosomal protein S2
RPS20 ribosomal protein S20
RPS21 ribosomal protein S21
RPS23 ribosomal protein S23
RPS24 ribosomal protein S24
RPS25 ribosomal protein S25
RPS26 ribosomal protein S26
RPS27 ribosomal protein S27
RPS27A ribosomal protein S27a
RPS28 ribosomal protein S28
RPS3 ribosomal protein S3
RPS3A ribosomal protein S3A
RPS4X ribosomal protein S4, X-linked
RPS5 ribosomal protein S5
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RPS7 ribosomal protein S7
RPS9 ribosomal protein S9
RPSA ribosomal protein SA
RTN3 reticulon 3
SH3GL1 SH3-domain GRB2-like 1
SH3GL2 SH3-domain GRB2-like 2
SH3KBP1 SH3-domain kinase binding protein 1
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SLITRK5 SLIT and NTRK-like family, member 5
SNX14 sorting nexin 14
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SQSTM1 sequestosome 1
SRPX2 sushi-repeat containing protein, X-linked 2
STX2 syntaxin 2
TAGLN3 transgelin 3
TBC1D24 TBC1 domain family, member 24
TDRD1 tudor domain containing 1
TDRD5 tudor domain containing 5
TDRD6 tudor domain containing 6
TPD52 tumor protein D52
TSC2 tuberous sclerosis 2
TTYH1 tweety family member 1
TUFM Tu translation elongation factor, mitochondrial
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
USP46 ubiquitin specific peptidase 46
VCAN versican
VCP valosin containing protein
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VGF VGF nerve growth factor inducible
VLDLR very low density lipoprotein receptor
WASF2 WAS protein family, member 2
WDR1 WD repeat domain 1
WIPF3 WAS/WASL interacting protein family, member 3
WNT3A wingless-type MMTV integration site family, member 3A
YBX1 Y box binding protein 1
YBX3 Y box binding protein 3
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta