synaptic vesicle endocytosis Gene Set
Dataset
GO Biological Process Annotations 2025
Category
structural or functional annotations
Type
biological process
Description
An endocytosis process that results in the invagination of the axonal plasma membrane to create a membrane-bounded vesicle. This process takes up excess membrane that would otherwise accumulate at the presynaptic terminal due to fusion of vesicle membranes during neurotransmitter release. The vesicles created may subsequently be used for neurotransmitter storage and release. (Gene Ontology , GO_0048488 )
External Link
http://amigo.geneontology.org/amigo/term/GO:0048488
Similar Terms
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Genes
30 genes participating in the synaptic vesicle endocytosis biological process from the curated GO Biological Process Annotations 2025 dataset.
Symbol
Name
AMPH
amphiphysin
AP2B1
adaptor-related protein complex 2, beta 1 subunit
AP2M1
adaptor-related protein complex 2, mu 1 subunit
AP2S1
adaptor-related protein complex 2, sigma 1 subunit
BLTP1
bridge-like lipid transfer protein family member 1
CANX
calnexin
CDK5
cyclin-dependent kinase 5
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
DNM1
dynamin 1
DNM2
dynamin 2
DNM3
dynamin 3
FCHO2
FCH domain only 2
GAK
cyclin G associated kinase
ITSN1
intersectin 1 (SH3 domain protein)
ITSN2
intersectin 2
MX1
MX dynamin-like GTPase 1
MX2
MX dynamin-like GTPase 2
NLGN3
neuroligin 3
OPHN1
oligophrenin 1
PACSIN1
protein kinase C and casein kinase substrate in neurons 1
PIP5K1C
phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
SNCB
synuclein, beta
SNCG
synuclein, gamma (breast cancer-specific protein 1)
STON1
stonin 1
STON2
stonin 2
STX1A
syntaxin 1A (brain)
SYNJ1
synaptojanin 1
SYNJ2
synaptojanin 2
VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
