syncope Gene Set

Dataset	GeneRIF Biological Term Annotations
Category	structural or functional annotations
Type	biological term
Description	Syncope refers to a generalized weakness of muscles with loss of postural tone, inability to stand upright, and loss of consciousness. Once the patient is in a horizontal position, blood flow to the brain is no longer hindered by gravitation and consciousness is regained. Unconsciousness usually lasts for seconds to minutes. Headache and drowsiness (which usually follow seizures) do not follow a syncopal attack. Syncope results from a sudden impairment of brain metabolism usually due to a reduction in cerebral blood flow. (Human Phenotype Ontology, HP_0001279)
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Genes

17 genes co-occuring with the biological term syncope in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol	Name
ACE	angiotensin I converting enzyme
ADORA2A	adenosine A2a receptor
ADRB1	adrenoceptor beta 1
ANK2	ankyrin 2, neuronal
CASQ2	calsequestrin 2 (cardiac muscle)
EDN1	endothelin 1
GAL	galanin/GMAP prepropeptide
GNAS	GNAS complex locus
GNB3	guanine nucleotide binding protein (G protein), beta polypeptide 3
KCNE3	potassium channel, voltage gated subfamily E regulatory beta subunit 3
KCNH2	potassium channel, voltage gated eag related subfamily H, member 2
KCNQ1	potassium channel, voltage gated KQT-like subfamily Q, member 1
NPPB	natriuretic peptide B
RGS2	regulator of G-protein signaling 2
RYR2	ryanodine receptor 2 (cardiac)
SCN5A	sodium channel, voltage gated, type V alpha subunit
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A