synostosis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A dysostosis that results_in abnormal fusing of adjacent bones. (Human Disease Ontology, DOID_11971)
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Genes

430 genes co-occuring with the disease synostosis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
FGFR2 fibroblast growth factor receptor 2 3.22923
FGFR3 fibroblast growth factor receptor 3 2.5082
MSX2 msh homeobox 2 2.34685
TWIST1 twist family bHLH transcription factor 1 2.2111
FGFR1 fibroblast growth factor receptor 1 2.13265
GLI3 GLI family zinc finger 3 2.12915
NOG noggin 1.99872
FRAS1 Fraser extracellular matrix complex subunit 1 1.89221
ARID1B AT rich interactive domain 1B (SWI1-like) 1.83636
NELL1 NEL-like 1 (chicken) 1.81149
HOXD13 homeobox D13 1.80066
EFNB1 ephrin-B1 1.77812
FREM2 FRAS1 related extracellular matrix protein 2 1.63142
RUNX2 runt-related transcription factor 2 1.61844
FREM1 FRAS1 related extracellular matrix 1 1.55779
FGF1 fibroblast growth factor 1 (acidic) 1.54142
RAB23 RAB23, member RAS oncogene family 1.51106
ALX4 ALX homeobox 4 1.46715
GJA1 gap junction protein, alpha 1, 43kDa 1.43244
DHCR7 7-dehydrocholesterol reductase 1.39346
SHH sonic hedgehog 1.38996
RECQL4 RecQ protein-like 4 1.38385
BMP4 bone morphogenetic protein 4 1.37861
IHH indian hedgehog 1.37294
GDF5 growth differentiation factor 5 1.36161
FGF10 fibroblast growth factor 10 1.34679
MSX1 msh homeobox 1 1.32891
FGF8 fibroblast growth factor 8 (androgen-induced) 1.29178
NCOA1 nuclear receptor coactivator 1 1.27214
FBXW4 F-box and WD repeat domain containing 4 1.26603
PVRL4 poliovirus receptor-related 4 1.25254
LMBR1 limb development membrane protein 1 1.24906
DLX5 distal-less homeobox 5 1.20223
FAM58A family with sequence similarity 58, member A 1.2018
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 1.16906
EVX2 even-skipped homeobox 2 1.1588
IL11RA interleukin 11 receptor, alpha 1.15155
BMP2 bone morphogenetic protein 2 1.14602
TGFB3 transforming growth factor, beta 3 1.1312
FLNB filamin B, beta 1.09965
PTER phosphotriesterase related 1.09923
FGF4 fibroblast growth factor 4 1.07782
SNX13 sorting nexin 13 1.07068
ZP2 zona pellucida glycoprotein 2 (sperm receptor) 1.07068
FGFR4 fibroblast growth factor receptor 4 1.03998
FGF9 fibroblast growth factor 9 1.03325
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 1.02735
POR P450 (cytochrome) oxidoreductase 1.02144
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 1.0168
DLX1 distal-less homeobox 1 1.01554
C1QTNF3 C1q and tumor necrosis factor related protein 3 1.01343
WDR35 WD repeat domain 35 0.981794
SMOC1 SPARC related modular calcium binding 1 0.981373
TP63 tumor protein p63 0.979689
FERD3L Fer3-like bHLH transcription factor 0.966663
FREM3 FRAS1 related extracellular matrix 3 0.948685
PTCH1 patched 1 0.944938
FBN1 fibrillin 1 0.938289
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.93207
ROR2 receptor tyrosine kinase-like orphan receptor 2 0.925039
FBN2 fibrillin 2 0.919673
ALPL alkaline phosphatase, liver/bone/kidney 0.919673
PJA1 praja ring finger 1, E3 ubiquitin protein ligase 0.918024
SHFM1 split hand/foot malformation (ectrodactyly) type 1 0.91308
C17ORF67 chromosome 17 open reading frame 67 0.895
TULP4 tubby like protein 4 0.888029
FGF7 fibroblast growth factor 7 0.887208
BMP7 bone morphogenetic protein 7 0.867549
ALPPL2 alkaline phosphatase, placental-like 2 0.866731
ALPP alkaline phosphatase, placental 0.866321
DNASE1L2 deoxyribonuclease I-like 2 0.862637
LRP4 low density lipoprotein receptor-related protein 4 0.855677
FGF2 fibroblast growth factor 2 (basic) 0.854859
MECOM MDS1 and EVI1 complex locus 0.847898
ADAMTS20 ADAM metallopeptidase with thrombospondin type 1 motif, 20 0.829869
HOXD12 homeobox D12 0.824128
FUZ fuzzy planar cell polarity protein 0.817155
KLF10 Kruppel-like factor 10 0.816745
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 0.814693
NUBP2 nucleotide binding protein 2 0.812232
TWISTNB TWIST neighbor 0.808949
ATRNL1 attractin-like 1 0.804436
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.790081
EFNA4 ephrin-A4 0.788033
TINAGL1 tubulointerstitial nephritis antigen-like 1 0.787623
FGFRL1 fibroblast growth factor receptor-like 1 0.785984
SOST sclerostin 0.785574
BMPR1B bone morphogenetic protein receptor, type IB 0.779023
HEMK1 HemK methyltransferase family member 1 0.772479
HOXD1 homeobox D1 0.766759
BGLAP bone gamma-carboxyglutamate (gla) protein 0.756971
NUBP1 nucleotide binding protein 1 0.75005
VWA2 von Willebrand factor A domain containing 2 0.74883
MEGF8 multiple EGF-like-domains 8 0.746798
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.746798
WNT9A wingless-type MMTV integration site family, member 9A 0.74436
IMPAD1 inositol monophosphatase domain containing 1 0.743547
NEK1 NIMA-related kinase 1 0.732191
EN1 engrailed homeobox 1 0.727333
BMP3 bone morphogenetic protein 3 0.724907
HOXD11 homeobox D11 0.724907
SOSTDC1 sclerostin domain containing 1 0.718039
KIF7 kinesin family member 7 0.718039
TCF12 transcription factor 12 0.707157
SOX9 SRY (sex determining region Y)-box 9 0.707157
COL26A1 collagen, type XXVI, alpha 1 0.705949
TGFB1 transforming growth factor, beta 1 0.705547
ISOC1 isochorismatase domain containing 1 0.699116
AXIN2 axin 2 0.695905
MNX1 motor neuron and pancreas homeobox 1 0.693098
OFD1 oral-facial-digital syndrome 1 0.683493
TGFB2 transforming growth factor, beta 2 0.682693
DLX6 distal-less homeobox 6 0.682294
PORCN porcupine homolog (Drosophila) 0.676308
CKAP5 cytoskeleton associated protein 5 0.671925
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 0.670333
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.662784
DDX11L8 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 like 8 0.662784
IRF6 interferon regulatory factor 6 0.651694
TGFBR1 transforming growth factor, beta receptor 1 0.635921
RNPS1 RNA binding protein S1, serine-rich domain 0.63042
LAMA5 laminin, alpha 5 0.629635
WNT7A wingless-type MMTV integration site family, member 7A 0.623751
BARX2 BARX homeobox 2 0.617877
HMX2 H6 family homeobox 2 0.617486
FBLN1 fibulin 1 0.616703
HAND2 heart and neural crest derivatives expressed 2 0.606543
EVC Ellis van Creveld protein 0.597961
COLEC11 collectin sub-family member 11 0.590558
CCNL2 cyclin L2 0.583941
FRS2 fibroblast growth factor receptor substrate 2 0.580828
GPC3 glypican 3 0.568386
MMP23B matrix metallopeptidase 23B 0.565666
SP7 Sp7 transcription factor 0.564889
HOXA4 homeobox A4 0.564112
GDF7 growth differentiation factor 7 0.560616
CHD2 chromodomain helicase DNA binding protein 2 0.556344
ASXL3 additional sex combs like transcriptional regulator 3 0.554015
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 0.552463
CDON cell adhesion associated, oncogene regulated 0.550134
STRA6 stimulated by retinoic acid 6 0.548583
HOXA13 homeobox A13 0.548195
ZFHX4 zinc finger homeobox 4 0.547032
RLIM ring finger protein, LIM domain interacting 0.544318
KLF7 Kruppel-like factor 7 (ubiquitous) 0.543155
FGF3 fibroblast growth factor 3 0.542767
DLG2 discs, large homolog 2 (Drosophila) 0.540055
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6 0.53657
IBSP integrin-binding sialoprotein 0.533475
CKM creatine kinase, muscle 0.531154
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 0.531154
BRD4 bromodomain containing 4 0.531154
YIPF4 Yip1 domain family, member 4 0.524974
PLS3 plastin 3 0.523816
CANT1 calcium activated nucleotidase 1 0.521888
FOXK2 forkhead box K2 0.514186
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 0.512264
CER1 cerberus 1, DAN family BMP antagonist 0.504973
PCYT1B phosphate cytidylyltransferase 1, choline, beta 0.503058
WIPF1 WAS/WASL interacting protein family, member 1 0.499997
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 0.496939
TWIST2 twist family bHLH transcription factor 2 0.495029
CHRDL1 chordin-like 1 0.493503
COL2A1 collagen, type II, alpha 1 0.491978
JAG1 jagged 1 0.483224
FGF18 fibroblast growth factor 18 0.481705
ERCC6 excision repair cross-complementation group 6 0.479047
MYO9A myosin IXA 0.477909
EIF6 eukaryotic translation initiation factor 6 0.47753
IGF1R insulin-like growth factor 1 receptor 0.470332
NPNT nephronectin 0.468441
GAS1 growth arrest-specific 1 0.468063
SPP1 secreted phosphoprotein 1 0.467684
ADAMTSL4 ADAMTS-like 4 0.460506
C3ORF18 chromosome 3 open reading frame 18 0.452208
HOXD8 homeobox D8 0.451831
LRP5 low density lipoprotein receptor-related protein 5 0.451454
ALX3 ALX homeobox 3 0.449947
MAPKAPK3 mitogen-activated protein kinase-activated protein kinase 3 0.446935
GDF11 growth differentiation factor 11 0.446182
HIP1 huntingtin interacting protein 1 0.445429
DOK7 docking protein 7 0.443923
ALX1 ALX homeobox 1 0.43941
MIR4315-2 microRNA 4315-2 0.438658
MIR4315-1 microRNA 4315-1 0.438658
WIF1 WNT inhibitory factor 1 0.433397
CTSK cathepsin K 0.432646
MAT1A methionine adenosyltransferase I, alpha 0.425139
E4F1 E4F transcription factor 1 0.420641
TCF3 transcription factor 3 0.416147
SALL1 spalt-like transcription factor 1 0.411283
ANKH ANKH inorganic pyrophosphate transport regulator 0.407919
HRAS Harvey rat sarcoma viral oncogene homolog 0.407545
GREM1 gremlin 1, DAN family BMP antagonist 0.402318
PGAM2 phosphoglycerate mutase 2 (muscle) 0.402318
EP300 E1A binding protein p300 0.39598
STARD8 StAR-related lipid transfer (START) domain containing 8 0.393001
PART1 prostate androgen-regulated transcript 1 (non-protein coding) 0.391513
SUFU suppressor of fused homolog (Drosophila) 0.389653
RAPSN receptor-associated protein of the synapse 0.387794
VPREB1 pre-B lymphocyte 1 0.387423
CIDEB cell death-inducing DFFA-like effector b 0.383337
FNDC3B fibronectin type III domain containing 3B 0.382223
SRA1 steroid receptor RNA activator 1 0.381852
NOTCH1 notch 1 0.379997
PRPS1L1 phosphoribosyl pyrophosphate synthetase 1-like 1 0.378514
OGN osteoglycin 0.37629
KIF27 kinesin family member 27 0.373698
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1 0.366671
CDK10 cyclin-dependent kinase 10 0.365562
IFT80 intraflagellar transport 80 0.365193
CHURC1 churchill domain containing 1 0.359657
ESRP1 epithelial splicing regulatory protein 1 0.357077
PYGO2 pygopus family PHD finger 2 0.355972
FAM120A family with sequence similarity 120A 0.347879
PHEX phosphate regulating endopeptidase homolog, X-linked 0.347144
CASS4 Cas scaffolding protein family member 4 0.346777
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa 0.344941
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.342006
PRRX1 paired related homeobox 1 0.338707
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.33651
STRC stereocilin 0.335046
STRCP1 stereocilin pseudogene 1 0.335046
ATRN attractin 0.33066
EFNA2 ephrin-A2 0.32701
SPTA1 spectrin, alpha, erythrocytic 1 0.321181
SH3PXD2B SH3 and PX domains 2B 0.318999
TNNT3 troponin T type 3 (skeletal, fast) 0.317182
BBS9 Bardet-Biedl syndrome 9 0.31464
DOCK3 dedicator of cytokinesis 3 0.313189
GRIP1 glutamate receptor interacting protein 1 0.311377
TBX5 T-box 5 0.311014
HOXD3 homeobox D3 0.302698
TBX4 T-box 4 0.299092
AKAP5 A kinase (PRKA) anchor protein 5 0.294772
GOSR2 golgi SNAP receptor complex member 2 0.294413
BAG4 BCL2-associated athanogene 4 0.292975
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.292616
BGN biglycan 0.291898
EBP emopamil binding protein (sterol isomerase) 0.290821
WNT2 wingless-type MMTV integration site family member 2 0.28831
TRPV6 transient receptor potential cation channel, subfamily V, member 6 0.287593
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 0.284371
DEFA1B defensin, alpha 1B 0.283655
DEFA1 defensin, alpha 1 0.283655
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.282582
GET4 golgi to ER traffic protein 4 homolog (S. cerevisiae) 0.267622
BMP10 bone morphogenetic protein 10 0.265494
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.261952
SFRP2 secreted frizzled-related protein 2 0.260538
CUL4B cullin 4B 0.254536
SP8 Sp8 transcription factor 0.253479
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.251366
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.246448
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 0.246098
PTPRO protein tyrosine phosphatase, receptor type, O 0.244696
LRP6 low density lipoprotein receptor-related protein 6 0.243995
PRAC1 prostate cancer susceptibility candidate 1 0.242595
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 0.242245
ABHD5 abhydrolase domain containing 5 0.240148
USB1 U6 snRNA biogenesis 1 0.237009
HMCN1 hemicentin 1 0.236312
SLC30A2 solute carrier family 30 (zinc transporter), member 2 0.235616
BMPR1A bone morphogenetic protein receptor, type IA 0.23492
EXT2 exostosin glycosyltransferase 2 0.233183
FGF6 fibroblast growth factor 6 0.231448
HOXD10 homeobox D10 0.228679
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog 0.227297
SYCN syncollin 0.223165
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A 0.22145
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.219398
GJC2 gap junction protein, gamma 2, 47kDa 0.217352
DLX4 distal-less homeobox 4 0.216672
NDE1 nudE neurodevelopment protein 1 0.214636
ADAM23 ADAM metallopeptidase domain 23 0.213283
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.212271
CNTN4 contactin 4 0.210253
RECQL5 RecQ protein-like 5 0.209918
ACPP acid phosphatase, prostate 0.209583
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3 0.208579
FN1 fibronectin 1 0.208245
DCN decorin 0.207578
BMP6 bone morphogenetic protein 6 0.206913
SP6 Sp6 transcription factor 0.20658
PTHLH parathyroid hormone-like hormone 0.199033
WRNIP1 Werner helicase interacting protein 1 0.198709
CHRD chordin 0.19742
TSHR thyroid stimulating hormone receptor 0.194548
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 0.189859
CLEC3A C-type lectin domain family 3, member A 0.188632
WRN Werner syndrome, RecQ helicase-like 0.187719
CLEC2B C-type lectin domain family 2, member B 0.18472
EVC2 Ellis van Creveld syndrome 2 0.182375
GRB2 growth factor receptor-bound protein 2 0.181222
SHOC2 soc-2 suppressor of clear homolog (C. elegans) 0.178403
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.177851
KIF3A kinesin family member 3A 0.177851
BHLHE41 basic helix-loop-helix family, member e41 0.176757
FMN1 formin 1 0.176757
SOX6 SRY (sex determining region Y)-box 6 0.175411
AMBN ameloblastin (enamel matrix protein) 0.174093
ZEB2 zinc finger E-box binding homeobox 2 0.171785
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.171535
INHBA inhibin, beta A 0.168617
CLEC10A C-type lectin domain family 10, member A 0.168148
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 0.165435
WWTR1 WW domain containing transcription regulator 1 0.164359
BHLHE40 basic helix-loop-helix family, member e40 0.163317
FURIN furin (paired basic amino acid cleaving enzyme) 0.160387
LAX1 lymphocyte transmembrane adaptor 1 0.160021
GDF6 growth differentiation factor 6 0.160021
KARS lysyl-tRNA synthetase 0.159838
ANOS1 anosmin 1 0.158605
GDF2 growth differentiation factor 2 0.158434
HOPX HOP homeobox 0.141425
CCM2 cerebral cavernous malformation 2 0.139944
OCM2 oncomodulin 2 0.139748
PHF12 PHD finger protein 12 0.139717
PTCH2 patched 2 0.139523
OCM oncomodulin 0.139442
ABHD14A abhydrolase domain containing 14A 0.139274
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha 0.138531
WNT11 wingless-type MMTV integration site family, member 11 0.137074
HSH2D hematopoietic SH2 domain containing 0.136932
TARP TCR gamma alternate reading frame protein 0.136159
RECQL RecQ helicase-like 0.135188
MEGF6 multiple EGF-like-domains 6 0.134989
C10ORF2 chromosome 10 open reading frame 2 0.134891
GCK glucokinase (hexokinase 4) 0.133044
SNRPN small nuclear ribonucleoprotein polypeptide N 0.131747
THEM4 thioesterase superfamily member 4 0.131214
ERCC2 excision repair cross-complementation group 2 0.130044
DNAH8 dynein, axonemal, heavy chain 8 0.114232
FGR FGR proto-oncogene, Src family tyrosine kinase 0.113121
NEFM neurofilament, medium polypeptide 0.111045
LRP2 low density lipoprotein receptor-related protein 2 0.110905
CTNND2 catenin (cadherin-associated protein), delta 2 0.110877
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.110766
DAD1 defender against cell death 1 0.110682
PHF6 PHD finger protein 6 0.109464
AMER1 APC membrane recruitment protein 1 0.109091
FGF19 fibroblast growth factor 19 0.108855
ADAM28 ADAM metallopeptidase domain 28 0.107724
ADD2 adducin 2 (beta) 0.107481
SMO smoothened, frizzled class receptor 0.107268
MTM1 myotubularin 1 0.106996
LOR loricrin 0.106684
BCOR BCL6 corepressor 0.106403
CISH cytokine inducible SH2-containing protein 0.106341
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 0.10584
EN2 engrailed homeobox 2 0.105616
SUOX sulfite oxidase 0.105328
SEPN1 selenoprotein N, 1 0.105104
TALDO1 transaldolase 1 0.105072
SMAD5 SMAD family member 5 0.104912
EPHA7 EPH receptor A7 0.10488
SRY sex determining region Y 0.104719
DLG3 discs, large homolog 3 (Drosophila) 0.103635
ACVR2A activin A receptor, type IIA 0.103568
CDAN1 codanin 1 0.103467
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.103332
GYPE glycophorin E (MNS blood group) 0.10313
PROKR2 prokineticin receptor 2 0.102559
SIX2 SIX homeobox 2 0.102388
WNT10B wingless-type MMTV integration site family, member 10B 0.102009
MYOT myotilin 0.101768
ILK integrin-linked kinase 0.101699
MAGEA4 melanoma antigen family A4 0.10163
ANXA1 annexin A1 0.10118
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.101145
CREBBP CREB binding protein 0.101109
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.10058
PVALB parvalbumin 0.10058
FOXM1 forkhead box M1 0.099654
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.098897
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.098789
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.098456
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) 0.098235
CA6 carbonic anhydrase VI 0.09805
MUSK muscle, skeletal, receptor tyrosine kinase 0.097903
MKKS McKusick-Kaufman syndrome 0.097866
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.097756
BBS4 Bardet-Biedl syndrome 4 0.097719
TBX3 T-box 3 0.096706
ASPH aspartate beta-hydroxylase 0.096556
COL7A1 collagen, type VII, alpha 1 0.096179
LHX3 LIM homeobox 3 0.096179
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.095833
GPC1 glypican 1 0.095525
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle) 0.094872
CPLX3 complexin 3 0.094637
MCM5 minichromosome maintenance complex component 5 0.09452
ZFX zinc finger protein, X-linked 0.094363
DSC3 desmocollin 3 0.093736
PROK2 prokineticin 2 0.092902
NUMB numb homolog (Drosophila) 0.092822
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 0.092782
NHS Nance-Horan syndrome (congenital cataracts and dental anomalies) 0.092263
TCOF1 Treacher Collins-Franceschetti syndrome 1 0.092144
OCA2 oculocutaneous albinism II 0.092104
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.091778
PGRMC1 progesterone receptor membrane component 1 0.09129
C6ORF25 chromosome 6 open reading frame 25 0.091209
SATB2 SATB homeobox 2 0.091087
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.091006
IGFBP1 insulin-like growth factor binding protein 1 0.090965
RHOA ras homolog family member A 0.090803
MARK3 MAP/microtubule affinity-regulating kinase 3 0.090803
SPAST spastin 0.09035
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 0.090309
LARGE like-glycosyltransferase 0.090309
TBX1 T-box 1 0.090102
NBN nibrin 0.090019
ATXN1 ataxin 1 0.089771
RBP4 retinol binding protein 4, plasma 0.089524
CHD7 chromodomain helicase DNA binding protein 7 0.089234
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.089108
JAG2 jagged 2 0.089108
HMX1 H6 family homeobox 1 0.088772
ANXA3 annexin A3 0.08852
NID1 nidogen 1 0.088184
KRT18 keratin 18, type I 0.088184
EPHB3 EPH receptor B3 0.086825
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 0.086783
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 0.086184
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 0.085968
PAX9 paired box 9 0.085968
SMAD2 SMAD family member 2 0.085535
ACVR1 activin A receptor, type I 0.085449
MCPH1 microcephalin 1 0.085362