synovia Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description A transparent viscid lubricating fluid secreted by a membrane of an articulation, bursa, or tendon sheath. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001339)
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Genes

383 proteins co-occuring with the tissue synovia in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
PHB2 prohibitin 2 2.22408
PRG4 proteoglycan 4 2.21879
MMP3 matrix metallopeptidase 3 2.13737
ACAN aggrecan 2.10432
COMP cartilage oligomeric matrix protein 2.09364
IL1B interleukin 1, beta 2.06317
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide 2.03054
CRP C-reactive protein, pentraxin-related 1.99109
TNF tumor necrosis factor 1.82657
MMP13 matrix metallopeptidase 13 1.73628
MMP1 matrix metallopeptidase 1 1.73031
TIMP1 TIMP metallopeptidase inhibitor 1 1.72036
PLA2G1B phospholipase A2, group IB (pancreas) 1.69948
CD4 CD4 molecule 1.69052
IL6 interleukin 6 1.58831
IL17A interleukin 17A 1.52188
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 1.46682
MMP9 matrix metallopeptidase 9 1.41722
CD79A CD79a molecule, immunoglobulin-associated alpha 1.40386
IL1A interleukin 1, alpha 1.38963
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 1.35222
ALB albumin 1.34496
MMP2 matrix metallopeptidase 2 1.3201
FN1 fibronectin 1 1.31244
IL1RN interleukin 1 receptor antagonist 1.29849
IL2 interleukin 2 1.29804
SERPINA2 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 2 (gene/pseudogene) 1.29759
CXCL8 chemokine (C-X-C motif) ligand 8 1.2922
HSPD1 heat shock 60kDa protein 1 (chaperonin) 1.28188
MRAP melanocortin 2 receptor accessory protein 1.28143
ACPP acid phosphatase, prostate 1.23851
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 1.23405
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 1.23004
CD68 CD68 molecule 1.20912
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 1.20111
B2M beta-2-microglobulin 1.19845
CCL2 chemokine (C-C motif) ligand 2 1.17181
S100A12 S100 calcium binding protein A12 1.1616
TGFB1 transforming growth factor, beta 1 1.14653
TIMP2 TIMP metallopeptidase inhibitor 2 1.14166
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 1.12394
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 1.10048
LTF lactotransferrin 1.08943
ELANE elastase, neutrophil expressed 1.08015
PLA2G10 phospholipase A2, group X 1.06823
MIA melanoma inhibitory activity 1.06691
GUSB glucuronidase, beta 1.05853
OSM oncostatin M 1.05589
CXCR3 chemokine (C-X-C motif) receptor 3 1.05061
CCR6 chemokine (C-C motif) receptor 6 1.05061
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.03829
CHI3L2 chitinase 3-like 2 1.03697
IL18 interleukin 18 1.03346
CD69 CD69 molecule 1.02644
TAC1 tachykinin, precursor 1 1.01506
UGDH UDP-glucose 6-dehydrogenase 1.01375
IL2RA interleukin 2 receptor, alpha 1.00632
CCL3 chemokine (C-C motif) ligand 3 0.994989
C5AR1 complement component 5a receptor 1 0.988032
IL10 interleukin 10 0.987162
S100A8 S100 calcium binding protein A8 0.975449
S100A9 S100 calcium binding protein A9 0.956428
PLG plasminogen 0.949531
MPO myeloperoxidase 0.946947
IL4 interleukin 4 0.941355
AMBP alpha-1-microglobulin/bikunin precursor 0.938777
PADI4 peptidyl arginine deiminase, type IV 0.925479
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.914361
CTSG cathepsin G 0.903275
MMP8 matrix metallopeptidase 8 0.903275
ICAM1 intercellular adhesion molecule 1 0.903275
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 0.89562
PLAA phospholipase A2-activating protein 0.883321
IGF1 insulin-like growth factor 1 (somatomedin C) 0.882897
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.868107
LYZ lysozyme 0.857574
CFP complement factor properdin 0.857574
CXCL10 chemokine (C-X-C motif) ligand 10 0.824849
TLR2 toll-like receptor 2 0.823594
SF3B3 splicing factor 3b, subunit 3, 130kDa 0.822757
GNG8 guanine nucleotide binding protein (G protein), gamma 8 0.822757
TLR4 toll-like receptor 4 0.81983
CCL20 chemokine (C-C motif) ligand 20 0.81983
ZNF658B zinc finger protein 658B, pseudogene 0.816486
ZNF658 zinc finger protein 658 0.816486
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 0.814815
IL34 interleukin 34 0.806465
KNG1 kininogen 1 0.806047
CTSK cathepsin K 0.804378
HP haptoglobin 0.802293
GPI glucose-6-phosphate isomerase 0.800208
FOXP3 forkhead box P3 0.794792
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.793543
HPR haptoglobin-related protein 0.790628
PADI2 peptidyl arginine deiminase, type II 0.781478
PRTN3 proteinase 3 0.77027
CTSB cathepsin B 0.769855
C1S complement component 1, s subcomponent 0.766539
SPP1 secreted phosphoprotein 1 0.761155
ALPPL2 alkaline phosphatase, placental-like 2 0.756604
ALPL alkaline phosphatase, liver/bone/kidney 0.755777
ALPP alkaline phosphatase, placental 0.75495
CXCL16 chemokine (C-X-C motif) ligand 16 0.750818
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11 0.738854
CXCL12 chemokine (C-X-C motif) ligand 12 0.723631
CP ceruloplasmin (ferroxidase) 0.721166
PLAU plasminogen activator, urokinase 0.720345
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.719524
SOD2 superoxide dismutase 2, mitochondrial 0.70845
CD44 CD44 molecule (Indian blood group) 0.707631
CD86 CD86 molecule 0.706402
CCL13 chemokine (C-C motif) ligand 13 0.705173
STEAP4 STEAP family member 4 0.700671
TRBV5-4 T cell receptor beta variable 5-4 0.698216
IL22 interleukin 22 0.690451
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.685551
CD80 CD80 molecule 0.683919
CD40 CD40 molecule, TNF receptor superfamily member 5 0.67821
FGF2 fibroblast growth factor 2 (basic) 0.675765
CXCR1 chemokine (C-X-C motif) receptor 1 0.674543
SELE selectin E 0.6721
RETN resistin 0.667622
VCAM1 vascular cell adhesion molecule 1 0.664775
CXCL5 chemokine (C-X-C motif) ligand 5 0.663962
BGLAP bone gamma-carboxyglutamate (gla) protein 0.663555
ADAMDEC1 ADAM-like, decysin 1 0.660304
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 0.654618
HYAL2 hyaluronoglucosaminidase 2 0.648127
PRELP proline/arginine-rich end leucine-rich repeat protein 0.644479
TRAC T cell receptor alpha constant 0.642048
IFNG interferon, gamma 0.640428
NAMPT nicotinamide phosphoribosyltransferase 0.634762
CXCR2 chemokine (C-X-C motif) receptor 2 0.632335
TF transferrin 0.631931
IGFBP3 insulin-like growth factor binding protein 3 0.630718
RAB6B RAB6B, member RAS oncogene family 0.624254
CCL5 chemokine (C-C motif) ligand 5 0.622639
SAA1 serum amyloid A1 0.620621
CTSS cathepsin S 0.6182
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.611346
CXCL9 chemokine (C-X-C motif) ligand 9 0.607319
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.606916
BMP7 bone morphogenetic protein 7 0.605306
IL15 interleukin 15 0.604099
LAIR2 leukocyte-associated immunoglobulin-like receptor 2 0.597666
FTH1 ferritin, heavy polypeptide 1 0.59405
NELFCD negative elongation factor complex member C/D 0.592444
CXCR6 chemokine (C-X-C motif) receptor 6 0.590437
CCL4 chemokine (C-C motif) ligand 4 0.587228
SSC5D scavenger receptor cysteine rich family, 5 domains 0.580417
PLSCR2 phospholipid scramblase 2 0.576816
FTL ferritin, light polypeptide 0.576816
CD27 CD27 molecule 0.57082
SEBOX SEBOX homeobox 0.57042
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 0.57042
IL16 interleukin 16 0.569622
UNC93A unc-93 homolog A (C. elegans) 0.569222
TGFB3 transforming growth factor, beta 3 0.568823
CD19 CD19 molecule 0.568025
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12 0.567227
NPS neuropeptide S 0.561644
PTGES prostaglandin E synthase 0.559652
LEP leptin 0.556865
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.555671
BPI bactericidal/permeability-increasing protein 0.555274
IL33 interleukin 33 0.551298
CD40LG CD40 ligand 0.546533
AGER advanced glycosylation end product-specific receptor 0.546136
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.545342
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.544549
SELL selectin L 0.540188
COL22A1 collagen, type XXII, alpha 1 0.540188
LTA lymphotoxin alpha 0.539793
IL32 interleukin 32 0.539
RNF2 ring finger protein 2 0.538604
MXRA5 matrix-remodelling associated 5 0.53267
FSTL1 follistatin-like 1 0.529903
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.528719
CCL22 chemokine (C-C motif) ligand 22 0.52635
SUN3 Sad1 and UNC84 domain containing 3 0.520829
SAA4 serum amyloid A4, constitutive 0.520041
SAA2 serum amyloid A2 0.519253
KLK1 kallikrein 1 0.518859
IL7 interleukin 7 0.518859
LAP3 leucine aminopeptidase 3 0.518072
CCL21 chemokine (C-C motif) ligand 21 0.511384
CCR1 chemokine (C-C motif) receptor 1 0.507457
TGFB2 transforming growth factor, beta 2 0.507064
F12 coagulation factor XII (Hageman factor) 0.50471
CFI complement factor I 0.504318
TADA1 transcriptional adaptor 1 0.497657
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.496874
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.494528
ACP1 acid phosphatase 1, soluble 0.493354
HMGB1 high mobility group box 1 0.490229
PRF1 perforin 1 (pore forming protein) 0.486326
CTSD cathepsin D 0.485935
C4A complement component 4A (Rodgers blood group) 0.478534
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.476979
HAS2 hyaluronan synthase 2 0.473869
B3GAT1 beta-1,3-glucuronyltransferase 1 0.469599
CCRL2 chemokine (C-C motif) receptor-like 2 0.468824
LGALS8 lectin, galactoside-binding, soluble, 8 0.465335
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.464174
AP3D1 adaptor-related protein complex 3, delta 1 subunit 0.462626
MYDGF myeloid-derived growth factor 0.461852
CD1C CD1c molecule 0.459532
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.458759
PPIA peptidylprolyl isomerase A (cyclophilin A) 0.458373
CALCA calcitonin-related polypeptide alpha 0.456055
FASLG Fas ligand (TNF superfamily, member 6) 0.454512
HCST hematopoietic cell signal transducer 0.452198
HAS3 hyaluronan synthase 3 0.449886
HAS1 hyaluronan synthase 1 0.447961
CAPG capping protein (actin filament), gelsolin-like 0.445653
HAPLN1 hyaluronan and proteoglycan link protein 1 0.444884
CD5 CD5 molecule 0.443731
DEK DEK proto-oncogene 0.442578
TLR5 toll-like receptor 5 0.43989
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 0.439123
IGHV4-39 immunoglobulin heavy variable 4-39 0.437205
CD5L CD5 molecule-like 0.432417
CD38 CD38 molecule 0.428783
TNC tenascin C 0.423818
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.423436
IGLV7-43 immunoglobulin lambda variable 7-43 0.415814
KIAA0101 KIAA0101 0.415053
MEFV Mediterranean fever 0.41087
MATN1 matrilin 1, cartilage matrix protein 0.407832
VNN2 vanin 2 0.407832
MMP7 matrix metallopeptidase 7 0.406315
ANXA5 annexin A5 0.405555
KLKB1 kallikrein B, plasma (Fletcher factor) 1 0.401386
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 0.400628
CCL17 chemokine (C-C motif) ligand 17 0.400628
NCAM1 neural cell adhesion molecule 1 0.40025
JUN jun proto-oncogene 0.399492
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 0.3976
ERCC6 excision repair cross-complementation group 6 0.397222
ANKH ANKH inorganic pyrophosphate transport regulator 0.396844
TFRC transferrin receptor 0.394576
ADA adenosine deaminase 0.393064
SPP2 secreted phosphoprotein 2, 24kDa 0.391553
CDA cytidine deaminase 0.38552
GPC4 glypican 4 0.384013
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.378748
MMP12 matrix metallopeptidase 12 0.375368
CXCL13 chemokine (C-X-C motif) ligand 13 0.372743
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 0.371619
TLR3 toll-like receptor 3 0.37087
NPY neuropeptide Y 0.367129
PID1 phosphotyrosine interaction domain containing 1 0.366381
CLEC4C C-type lectin domain family 4, member C 0.366007
IFNA1 interferon, alpha 1 0.363766
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.361901
CAT catalase 0.359292
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 0.359292
C1R complement component 1, r subcomponent 0.35743
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.35557
IL23A interleukin 23, alpha subunit p19 0.352598
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.351485
THY1 Thy-1 cell surface antigen 0.350001
ANPEP alanyl (membrane) aminopeptidase 0.347038
HBA2 hemoglobin, alpha 2 0.347038
IL21 interleukin 21 0.347038
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.346668
CXCL2 chemokine (C-X-C motif) ligand 2 0.344818
MATN3 matrilin 3 0.342602
VASN vasorin 0.341126
TTK TTK protein kinase 0.339835
ATP1A1-AS1 ATP1A1 antisense RNA 1 0.338914
ADIPOR1 adiponectin receptor 1 0.338177
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.336336
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.335233
CXCL11 chemokine (C-X-C motif) ligand 11 0.334865
C3 complement component 3 0.333028
C1QA complement component 1, q subcomponent, A chain 0.33156
FGF1 fibroblast growth factor 1 (acidic) 0.331194
ALOX5 arachidonate 5-lipoxygenase 0.329361
CHID1 chitinase domain containing 1 0.328262
IBSP integrin-binding sialoprotein 0.32753
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.326798
CORO1A coronin, actin binding protein, 1A 0.325335
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.32205
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 0.32205
CD58 CD58 molecule 0.319863
TIMP3 TIMP metallopeptidase inhibitor 3 0.319498
HEXDC hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing 0.318407
PI16 peptidase inhibitor 16 0.317679
NGF nerve growth factor (beta polypeptide) 0.31332
TREM2 triggering receptor expressed on myeloid cells 2 0.312595
BMP2 bone morphogenetic protein 2 0.306805
CD83 CD83 molecule 0.306083
IL6R interleukin 6 receptor 0.303198
CD163 CD163 molecule 0.302838
SOD3 superoxide dismutase 3, extracellular 0.30032
TLR7 toll-like receptor 7 0.29996
CSN1S1 casein alpha s1 0.29996
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.299242
FPR2 formyl peptide receptor 2 0.298524
MCAM melanoma cell adhesion molecule 0.298524
COL2A1 collagen, type II, alpha 1 0.297806
PDCD5 programmed cell death 5 0.295655
MGEA5 meningioma expressed antigen 5 (hyaluronidase) 0.28887
CRTAC1 cartilage acidic protein 1 0.288158
HBA1 hemoglobin, alpha 1 0.287447
KLRD1 killer cell lectin-like receptor subfamily D, member 1 0.286026
AHSG alpha-2-HS-glycoprotein 0.286026
IL7R interleukin 7 receptor 0.285671
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 0.284253
LCA10 lung carcinoma-associated 10 0.281776
CCR7 chemokine (C-C motif) receptor 7 0.278955
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.277197
CCL23 chemokine (C-C motif) ligand 23 0.276495
CCR2 chemokine (C-C motif) receptor 2 0.275794
FGL2 fibrinogen-like 2 0.274569
RIN2 Ras and Rab interactor 2 0.2723
HDAC7 histone deacetylase 7 0.271778
CTGF connective tissue growth factor 0.270909
CCR3 chemokine (C-C motif) receptor 3 0.270561
PGF placental growth factor 0.269521
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.266757
PIH2 pregnancy-induced hypertension syndrome-related protein 0.266069
KRT36 keratin 36, type I 0.264696
HYAL4 hyaluronoglucosaminidase 4 0.264353
STAT1 signal transducer and activator of transcription 1, 91kDa 0.262986
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 0.262645
XCR1 chemokine (C motif) receptor 1 0.25858
ADIPOR2 adiponectin receptor 2 0.257907
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 0.256902
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.256234
PRAMEF20 PRAME family member 20 0.250953
PLAT plasminogen activator, tissue 0.248683
IGHV3-9 immunoglobulin heavy variable 3-9 0.245491
OAT ornithine aminotransferase 0.244545
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.242983
SUMF2 sulfatase modifying factor 2 0.24052
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.238108
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 0.237513
ADAM22 ADAM metallopeptidase domain 22 0.237216
BTK Bruton agammaglobulinemia tyrosine kinase 0.236627
PLA2G2D phospholipase A2, group IID 0.236332
CCL25 chemokine (C-C motif) ligand 25 0.235167
NXT1 nuclear transport factor 2-like export factor 1 0.231482
LGALS1 lectin, galactoside-binding, soluble, 1 0.229839
TYMP thymidine phosphorylase 0.229568
GPD1L glycerol-3-phosphate dehydrogenase 1-like 0.22797
CALCR calcitonin receptor 0.226667
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.226411
HYAL1 hyaluronoglucosaminidase 1 0.226155
ENO1 enolase 1, (alpha) 0.225647
IL13 interleukin 13 0.225395
IDO1 indoleamine 2,3-dioxygenase 1 0.22415
CXCR5 chemokine (C-X-C motif) receptor 5 0.223906
GC group-specific component (vitamin D binding protein) 0.223662
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.223662
PADI3 peptidyl arginine deiminase, type III 0.223177
VWF von Willebrand factor 0.222224
TLR9 toll-like receptor 9 0.222224
C5 complement component 5 0.221755
HLA-C major histocompatibility complex, class I, C 0.220604
C4BPA complement component 4 binding protein, alpha 0.21883
LGALS3 lectin, galactoside-binding, soluble, 3 0.218613
UBC ubiquitin C 0.218186
CAST calpastatin 0.217762
CARD17 caspase recruitment domain family, member 17 0.216325
MIR146A microRNA 146a 0.216325
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 0.216126
GPX5 glutathione peroxidase 5 0.214765
FMOD fibromodulin 0.214576
SDC3 syndecan 3 0.214576
CST4 cystatin S 0.214202
RPS27A ribosomal protein S27a 0.213833
A2M alpha-2-macroglobulin 0.21365
GPX4 glutathione peroxidase 4 0.212936
RASIP1 Ras interacting protein 1 0.212761
CCL4L2 chemokine (C-C motif) ligand 4-like 2 0.203388
CCL4L1 chemokine (C-C motif) ligand 4-like 1 0.202739
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.199481
S100A4 S100 calcium binding protein A4 0.196218
MNDA myeloid cell nuclear differentiation antigen 0.195865
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.194873
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.192793