synthetic Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

182 genes co-occuring with the biological term synthetic in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCC6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACKR3 atypical chemokine receptor 3
ACVR1B activin A receptor, type IB
ADIPOQ adiponectin, C1Q and collagen domain containing
ADORA2A adenosine A2a receptor
ADRA2A adrenoceptor alpha 2A
AFP alpha-fetoprotein
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALB albumin
ALOXE3 arachidonate lipoxygenase 3
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
APOA1 apolipoprotein A-I
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AR androgen receptor
ATR ATR serine/threonine kinase
BAK1 BCL2-antagonist/killer 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BLM Bloom syndrome, RecQ helicase-like
BMP2 bone morphogenetic protein 2
C3 complement component 3
C5AR1 complement component 5a receptor 1
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCL22 chemokine (C-C motif) ligand 22
CCNE1 cyclin E1
CD14 CD14 molecule
CD1D CD1d molecule
CDC42 cell division cycle 42
CFI complement factor I
CGB chorionic gonadotropin, beta polypeptide
CIB1 calcium and integrin binding 1 (calmyrin)
CKAP4 cytoskeleton-associated protein 4
CLP1 cleavage and polyadenylation factor I subunit 1
CNR1 cannabinoid receptor 1 (brain)
CNR2 cannabinoid receptor 2 (macrophage)
CREB1 cAMP responsive element binding protein 1
CRYAB crystallin, alpha B
CSNK1E casein kinase 1, epsilon
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCR4 chemokine (C-X-C motif) receptor 4
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEFB106A defensin, beta 106A
EDN1 endothelin 1
EGFR epidermal growth factor receptor
ELN elastin
ERCC1 excision repair cross-complementation group 1
ESR1 estrogen receptor 1
ESRRA estrogen-related receptor alpha
F10 coagulation factor X
F12 coagulation factor XII (Hageman factor)
F2 coagulation factor II (thrombin)
F3 coagulation factor III (thromboplastin, tissue factor)
F8 coagulation factor VIII, procoagulant component
FADS2 fatty acid desaturase 2
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
FEN1 flap structure-specific endonuclease 1
FFAR4 free fatty acid receptor 4
FGF1 fibroblast growth factor 1 (acidic)
FUT2 fucosyltransferase 2 (secretor status included)
G6PC2 glucose-6-phosphatase, catalytic, 2
GABARAP GABA(A) receptor-associated protein
GADD45A growth arrest and DNA-damage-inducible, alpha
GH1 growth hormone 1
GPER1 G protein-coupled estrogen receptor 1
GPR1 G protein-coupled receptor 1
GSN gelsolin
HAMP hepcidin antimicrobial peptide
HAS1 hyaluronan synthase 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HSPA1B heat shock 70kDa protein 1B
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGF1 insulin-like growth factor 1 (somatomedin C)
IL13 interleukin 13
IL2 interleukin 2
INSL3 insulin-like 3 (Leydig cell)
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
KCTD15 potassium channel tetramerization domain containing 15
KLK6 kallikrein-related peptidase 6
KRT6A keratin 6A, type II
LYZ lysozyme
MAML1 mastermind-like 1 (Drosophila)
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MBTPS1 membrane-bound transcription factor peptidase, site 1
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
MIR143 microRNA 143
MIR145 microRNA 145
MIR29A microRNA 29a
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUS81 MUS81 structure-specific endonuclease subunit
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAMPT nicotinamide phosphoribosyltransferase
NAPRT nicotinate phosphoribosyltransferase
NCAM1 neural cell adhesion molecule 1
NMD3 NMD3 ribosome export adaptor
NR1H2 nuclear receptor subfamily 1, group H, member 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR5A1 nuclear receptor subfamily 5, group A, member 1
NR5A2 nuclear receptor subfamily 5, group A, member 2
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PCSK1 proprotein convertase subtilisin/kexin type 1
PDGFB platelet-derived growth factor beta polypeptide
PGR progesterone receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PNKP polynucleotide kinase 3'-phosphatase
POLQ polymerase (DNA directed), theta
POLRMT polymerase (RNA) mitochondrial (DNA directed)
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PRKCE protein kinase C, epsilon
PRRC2A proline-rich coiled-coil 2A
PSEN1 presenilin 1
PTAFR platelet-activating factor receptor
PTEN phosphatase and tensin homolog
PTN pleiotrophin
RAD23A RAD23 homolog A (S. cerevisiae)
RAD54B RAD54 homolog B (S. cerevisiae)
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RECQL5 RecQ protein-like 5
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RORA RAR-related orphan receptor A
RPA1 replication protein A1, 70kDa
RPS6 ribosomal protein S6
RXFP2 relaxin/insulin-like family peptide receptor 2
RXRA retinoid X receptor, alpha
SAE1 SUMO1 activating enzyme subunit 1
SCNN1G sodium channel, non voltage gated 1 gamma subunit
SEC16B SEC16 homolog B (S. cerevisiae)
SEC23A Sec23 homolog A (S. cerevisiae)
SEC24C SEC24 family member C
SELPLG selectin P ligand
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SH2B1 SH2B adaptor protein 1
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMN2 survival of motor neuron 2, centromeric
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD1 superoxide dismutase 1, soluble
SOX9 SRY (sex determining region Y)-box 9
SPHK1 sphingosine kinase 1
SREBF1 sterol regulatory element binding transcription factor 1
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
STAR steroidogenic acute regulatory protein
TDGF1 teratocarcinoma-derived growth factor 1
TEK TEK tyrosine kinase, endothelial
TFF1 trefoil factor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNNI3 troponin I type 3 (cardiac)
TP53 tumor protein p53
TRD T cell receptor delta locus
TRG T cell receptor gamma locus
TRPM7 transient receptor potential cation channel, subfamily M, member 7
UBA2 ubiquitin-like modifier activating enzyme 2
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
VCAN versican
VWF von Willebrand factor
WRN Werner syndrome, RecQ helicase-like
WWOX WW domain containing oxidoreductase
XPO1 exportin 1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta