| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the syrosingopine-1761 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| ADAM8 | ADAM metallopeptidase domain 8 |
| AES | amino-terminal enhancer of split |
| ALMS1 | Alstrom syndrome protein 1 |
| ALOXE3 | arachidonate lipoxygenase 3 |
| APP | amyloid beta (A4) precursor protein |
| ARL4C | ADP-ribosylation factor-like 4C |
| ARMC7 | armadillo repeat containing 7 |
| ATG4B | autophagy related 4B, cysteine peptidase |
| C5ORF45 | chromosome 5 open reading frame 45 |
| C9ORF114 | chromosome 9 open reading frame 114 |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CACYBP | calcyclin binding protein |
| CCDC40 | coiled-coil domain containing 40 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CD86 | CD86 molecule |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CPNE1 | copine I |
| CREM | cAMP responsive element modulator |
| CSNK1D | casein kinase 1, delta |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
| DEAF1 | DEAF1 transcription factor |
| DGCR14 | DiGeorge syndrome critical region gene 14 |
| DOLK | dolichol kinase |
| DUSP4 | dual specificity phosphatase 4 |
| ELMO2 | engulfment and cell motility 2 |
| FMOD | fibromodulin |
| FTH1 | ferritin, heavy polypeptide 1 |
| FZD4 | frizzled class receptor 4 |
| GAB2 | GRB2-associated binding protein 2 |
| GABPB1 | GA binding protein transcription factor, beta subunit 1 |
| GAS2L1 | growth arrest-specific 2 like 1 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GLRX3 | glutaredoxin 3 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| HEG1 | heart development protein with EGF-like domains 1 |
| HMOX1 | heme oxygenase 1 |
| IDS | iduronate 2-sulfatase |
| IL1RN | interleukin 1 receptor antagonist |
| IL24 | interleukin 24 |
| INHBA | inhibin, beta A |
| INTS5 | integrator complex subunit 5 |
| JAG1 | jagged 1 |
| JOSD1 | Josephin domain containing 1 |
| KIF3C | kinesin family member 3C |
| KIZ | kizuna centrosomal protein |
| KYNU | kynureninase |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LSP1 | lymphocyte-specific protein 1 |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
| MCL1 | myeloid cell leukemia 1 |
| MPV17 | MpV17 mitochondrial inner membrane protein |
| MPZL1 | myelin protein zero-like 1 |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
| NIPAL2 | NIPA-like domain containing 2 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NSD1 | nuclear receptor binding SET domain protein 1 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PILRA | paired immunoglobin-like type 2 receptor alpha |
| PPAP2A | phosphatidic acid phosphatase type 2A |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRDM4 | PR domain containing 4 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RAB11B | RAB11B, member RAS oncogene family |
| RBM14 | RNA binding motif protein 14 |
| RGS12 | regulator of G-protein signaling 12 |
| RHOB | ras homolog family member B |
| RUNX1 | runt-related transcription factor 1 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| SDC2 | syndecan 2 |
| SEC22B | SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene) |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SFSWAP | splicing factor, suppressor of white-apricot family |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha |
| SH2D1A | SH2 domain containing 1A |
| SH2D3A | SH2 domain containing 3A |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC6A3 | solute carrier family 6 (neurotransmitter transporter), member 3 |
| SLN | sarcolipin |
| SMG5 | SMG5 nonsense mediated mRNA decay factor |
| SNAPC4 | small nuclear RNA activating complex, polypeptide 4, 190kDa |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TARP | TCR gamma alternate reading frame protein |
| TEX40 | testis expressed 40 |
| THBS1 | thrombospondin 1 |
| TNS1 | tensin 1 |
| TRAF1 | TNF receptor-associated factor 1 |
| YIPF2 | Yip1 domain family, member 2 |
| YIPF4 | Yip1 domain family, member 4 |
| ZSCAN32 | zinc finger and SCAN domain containing 32 |
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ACYP2 | acylphosphatase 2, muscle type |
| ADRB2 | adrenoceptor beta 2, surface |
| AGL | amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| ARFGAP2 | ADP-ribosylation factor GTPase activating protein 2 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| ATP11B | ATPase, class VI, type 11B |
| AZI2 | 5-azacytidine induced 2 |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BRIX1 | BRX1, biogenesis of ribosomes |
| BRPF1 | bromodomain and PHD finger containing, 1 |
| C17ORF85 | chromosome 17 open reading frame 85 |
| C1D | C1D nuclear receptor corepressor |
| C5ORF28 | chromosome 5 open reading frame 28 |
| CASP8AP2 | caspase 8 associated protein 2 |
| CBFA2T3 | core-binding factor, runt domain, alpha subunit 2; translocated to, 3 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD302 | CD302 molecule |
| CD69 | CD69 molecule |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CISH | cytokine inducible SH2-containing protein |
| CLASP1 | cytoplasmic linker associated protein 1 |
| CPOX | coproporphyrinogen oxidase |
| CSF3R | colony stimulating factor 3 receptor (granulocyte) |
| DCP2 | decapping mRNA 2 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 |
| DPYSL2 | dihydropyrimidinase-like 2 |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 |
| FAM46A | family with sequence similarity 46, member A |
| FLT3 | fms-related tyrosine kinase 3 |
| GBAS | glioblastoma amplified sequence |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like |
| HDAC4 | histone deacetylase 4 |
| HEATR3 | HEAT repeat containing 3 |
| HIRA | histone cell cycle regulator |
| HMG20A | high mobility group 20A |
| IMPACT | impact RWD domain protein |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KIFAP3 | kinesin-associated protein 3 |
| LACTB2 | lactamase, beta 2 |
| LBR | lamin B receptor |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| MEAF6 | MYST/Esa1-associated factor 6 |
| MED4 | mediator complex subunit 4 |
| MEST | mesoderm specific transcript |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MNDA | myeloid cell nuclear differentiation antigen |
| MPP1 | membrane protein, palmitoylated 1, 55kDa |
| MRPL2 | mitochondrial ribosomal protein L2 |
| MSL2 | male-specific lethal 2 homolog (Drosophila) |
| MYL12B | myosin, light chain 12B, regulatory |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| NDE1 | nudE neurodevelopment protein 1 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NUBP2 | nucleotide binding protein 2 |
| NUCB2 | nucleobindin 2 |
| NUP93 | nucleoporin 93kDa |
| OIP5 | Opa interacting protein 5 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PCNP | PEST proteolytic signal containing nuclear protein |
| PDSS2 | prenyl (decaprenyl) diphosphate synthase, subunit 2 |
| PEX12 | peroxisomal biogenesis factor 12 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PLCD1 | phospholipase C, delta 1 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PPCS | phosphopantothenoylcysteine synthetase |
| PPM1G | protein phosphatase, Mg2+/Mn2+ dependent, 1G |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 |
| PPT1 | palmitoyl-protein thioesterase 1 |
| PRR3 | proline rich 3 |
| PTBP2 | polypyrimidine tract binding protein 2 |
| RBM7 | RNA binding motif protein 7 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RPAP3 | RNA polymerase II associated protein 3 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RSBN1 | round spermatid basic protein 1 |
| SF3B4 | splicing factor 3b, subunit 4, 49kDa |
| SIRT6 | sirtuin 6 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SLMO2 | slowmo homolog 2 (Drosophila) |
| SS18L1 | synovial sarcoma translocation gene on chromosome 18-like 1 |
| SSFA2 | sperm specific antigen 2 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) |
| TFB2M | transcription factor B2, mitochondrial |
| TJP2 | tight junction protein 2 |
| TMBIM4 | transmembrane BAX inhibitor motif containing 4 |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TRAPPC2L | trafficking protein particle complex 2-like |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) |
| TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) |
| TTBK2 | tau tubulin kinase 2 |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) |
| ZNF426 | zinc finger protein 426 |
