| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
197 genes differentially expressed following the syrosingopine-2753 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ANKRD12 | ankyrin repeat domain 12 |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ARMC8 | armadillo repeat containing 8 |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| ATF3 | activating transcription factor 3 |
| ATP5C1 | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 |
| BEX4 | brain expressed, X-linked 4 |
| CCNG2 | cyclin G2 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CLGN | calmegin |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DBP | D site of albumin promoter (albumin D-box) binding protein |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DTNA | dystrobrevin, alpha |
| EFNB3 | ephrin-B3 |
| EGR1 | early growth response 1 |
| ENO2 | enolase 2 (gamma, neuronal) |
| EPOR | erythropoietin receptor |
| FASN | fatty acid synthase |
| FHL1 | four and a half LIM domains 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GMPR | guanosine monophosphate reductase |
| GRB10 | growth factor receptor-bound protein 10 |
| GTPBP2 | GTP binding protein 2 |
| HDAC5 | histone deacetylase 5 |
| HIST1H2BJ | histone cluster 1, H2bj |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HSD17B14 | hydroxysteroid (17-beta) dehydrogenase 14 |
| ICAM1 | intercellular adhesion molecule 1 |
| IL21R | interleukin 21 receptor |
| INHBE | inhibin, beta E |
| INSIG1 | insulin induced gene 1 |
| KIF5C | kinesin family member 5C |
| KLF9 | Kruppel-like factor 9 |
| KLHL24 | kelch-like family member 24 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LOC157562 | uncharacterized LOC157562 |
| LPIN1 | lipin 1 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MARS | methionyl-tRNA synthetase |
| MED6 | mediator complex subunit 6 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 |
| MST1 | macrophage stimulating 1 |
| MTSS1 | metastasis suppressor 1 |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NDE1 | nudE neurodevelopment protein 1 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OPTN | optineurin |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PDE9A | phosphodiesterase 9A |
| PER1 | period circadian clock 1 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PRSS8 | protease, serine, 8 |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RNASE4 | ribonuclease, RNase A family, 4 |
| RTN2 | reticulon 2 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SIRT4 | sirtuin 4 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SRCAP | Snf2-related CREBBP activator protein |
| SSBP1 | single-stranded DNA binding protein 1, mitochondrial |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| SYNGR3 | synaptogyrin 3 |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TBX19 | T-box 19 |
| THAP3 | THAP domain containing, apoptosis associated protein 3 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TRIM2 | tripartite motif containing 2 |
| TRIM36 | tripartite motif containing 36 |
| TXNIP | thioredoxin interacting protein |
| ULBP2 | UL16 binding protein 2 |
| USB1 | U6 snRNA biogenesis 1 |
| VEGFA | vascular endothelial growth factor A |
| VLDLR | very low density lipoprotein receptor |
| WDR59 | WD repeat domain 59 |
| WSB1 | WD repeat and SOCS box containing 1 |
| YPEL5 | yippee-like 5 (Drosophila) |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZNF277 | zinc finger protein 277 |
| ZNF821 | zinc finger protein 821 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| AGR2 | anterior gradient 2 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| B9D2 | B9 protein domain 2 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BFSP1 | beaded filament structural protein 1, filensin |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C2ORF54 | chromosome 2 open reading frame 54 |
| C4ORF19 | chromosome 4 open reading frame 19 |
| C5AR2 | complement component 5a receptor 2 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCNE2 | cyclin E2 |
| CENPO | centromere protein O |
| CFAP44 | cilia and flagella associated protein 44 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CTDSP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DEAF1 | DEAF1 transcription factor |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ERCC4 | excision repair cross-complementation group 4 |
| FAM189A2 | family with sequence similarity 189, member A2 |
| FASTKD5 | FAST kinase domains 5 |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| HDAC4 | histone deacetylase 4 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIRA | histone cell cycle regulator |
| HIST1H4F | histone cluster 1, H4f |
| HOXC13 | homeobox C13 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| IFT22 | intraflagellar transport 22 |
| IL17RB | interleukin 17 receptor B |
| IMP3 | IMP3, U3 small nucleolar ribonucleoprotein |
| IQCG | IQ motif containing G |
| JMJD4 | jumonji domain containing 4 |
| KIAA0125 | KIAA0125 |
| KITLG | KIT ligand |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| MEPCE | methylphosphate capping enzyme |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MPHOSPH8 | M-phase phosphoprotein 8 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MTHFS | 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NPY5R | neuropeptide Y receptor Y5 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PC | pyruvate carboxylase |
| PIGH | phosphatidylinositol glycan anchor biosynthesis, class H |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| POLH | polymerase (DNA directed), eta |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RIC8B | RIC8 guanine nucleotide exchange factor B |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RPAP1 | RNA polymerase II associated protein 1 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SIDT1 | SID1 transmembrane family, member 1 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| TET3 | tet methylcytosine dioxygenase 3 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TMEM209 | transmembrane protein 209 |
| TMPRSS3 | transmembrane protease, serine 3 |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TRIM25 | tripartite motif containing 25 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TWISTNB | TWIST neighbor |
| UBIAD1 | UbiA prenyltransferase domain containing 1 |
| UQCC1 | ubiquinol-cytochrome c reductase complex assembly factor 1 |
| USP36 | ubiquitin specific peptidase 36 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| VGF | VGF nerve growth factor inducible |
| WDR76 | WD repeat domain 76 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 |
| ZNF480 | zinc finger protein 480 |
| ZNF611 | zinc finger protein 611 |
| ZNF652 | zinc finger protein 652 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
| ZXDC | ZXD family zinc finger C |
