| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the syrosingopine-5733 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADD2 | adducin 2 (beta) |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| AIM1L | absent in melanoma 1-like |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ANGPTL4 | angiopoietin-like 4 |
| APAF1 | apoptotic peptidase activating factor 1 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARMC8 | armadillo repeat containing 8 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ARTN | artemin |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| BBC3 | BCL2 binding component 3 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CBLC | Cbl proto-oncogene C, E3 ubiquitin protein ligase |
| CCNG2 | cyclin G2 |
| CD24 | CD24 molecule |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CORO1A | coronin, actin binding protein, 1A |
| CTH | cystathionine gamma-lyase |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DENND3 | DENN/MADD domain containing 3 |
| DUSP1 | dual specificity phosphatase 1 |
| EDA | ectodysplasin A |
| EGR2 | early growth response 2 |
| ESR1 | estrogen receptor 1 |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FAM63B | family with sequence similarity 63, member B |
| FGFBP1 | fibroblast growth factor binding protein 1 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FLOT1 | flotillin 1 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| GK | glycerol kinase |
| GP6 | glycoprotein VI (platelet) |
| GTPBP2 | GTP binding protein 2 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HIC2 | hypermethylated in cancer 2 |
| IL11 | interleukin 11 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase |
| LMTK1 | lemur tail kinase 1 |
| LUM | lumican |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| NEK3 | NIMA-related kinase 3 |
| NF1 | neurofibromin 1 |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PDE10A | phosphodiesterase 10A |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDPN | podoplanin |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| PTGES | prostaglandin E synthase |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| RBM34 | RNA binding motif protein 34 |
| RIMS3 | regulating synaptic membrane exocytosis 3 |
| RND1 | Rho family GTPase 1 |
| S100P | S100 calcium binding protein P |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SDS | serine dehydratase |
| SEPP1 | selenoprotein P, plasma, 1 |
| SH2D3A | SH2 domain containing 3A |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STC1 | stanniocalcin 1 |
| STON1 | stonin 1 |
| STRN3 | striatin, calmodulin binding protein 3 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 |
| TPMT | thiopurine S-methyltransferase |
| TRIM29 | tripartite motif containing 29 |
| TRPA1 | transient receptor potential cation channel, subfamily A, member 1 |
| TSC22D2 | TSC22 domain family, member 2 |
| UBE3A | ubiquitin protein ligase E3A |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZBTB18 | zinc finger and BTB domain containing 18 |
| ZNF639 | zinc finger protein 639 |
| ZSCAN18 | zinc finger and SCAN domain containing 18 |
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| ANAPC2 | anaphase promoting complex subunit 2 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ARL15 | ADP-ribosylation factor-like 15 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCDC9 | coiled-coil domain containing 9 |
| CENPO | centromere protein O |
| CFAP44 | cilia and flagella associated protein 44 |
| CLDN14 | claudin 14 |
| COBL | cordon-bleu WH2 repeat protein |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 |
| CRYBA2 | crystallin, beta A2 |
| CTGF | connective tissue growth factor |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| CYP7B1 | cytochrome P450, family 7, subfamily B, polypeptide 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DNAJC11 | DnaJ (Hsp40) homolog, subfamily C, member 11 |
| EDC4 | enhancer of mRNA decapping 4 |
| EFNA3 | ephrin-A3 |
| EHD3 | EH-domain containing 3 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| FAM50B | family with sequence similarity 50, member B |
| FAM53B | family with sequence similarity 53, member B |
| FANCC | Fanconi anemia, complementation group C |
| FBXL14 | F-box and leucine-rich repeat protein 14 |
| FNTB | farnesyltransferase, CAAX box, beta |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| HDAC7 | histone deacetylase 7 |
| HIRA | histone cell cycle regulator |
| HIST1H3B | histone cluster 1, H3b |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| INHBB | inhibin, beta B |
| INTS7 | integrator complex subunit 7 |
| IQCG | IQ motif containing G |
| KEAP1 | kelch-like ECH-associated protein 1 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MEPCE | methylphosphate capping enzyme |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MTA2 | metastasis associated 1 family, member 2 |
| MTCL1 | microtubule crosslinking factor 1 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MYL5 | myosin, light chain 5, regulatory |
| NARFL | nuclear prelamin A recognition factor-like |
| NDP | Norrie disease (pseudoglioma) |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NPY1R | neuropeptide Y receptor Y1 |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PEG3 | paternally expressed 3 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PISD | phosphatidylserine decarboxylase |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PMM2 | phosphomannomutase 2 |
| POGLUT1 | protein O-glucosyltransferase 1 |
| POM121 | POM121 transmembrane nucleoporin |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRKX | protein kinase, X-linked |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| PUS1 | pseudouridylate synthase 1 |
| RAB3A | RAB3A, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SCHIP1 | schwannomin interacting protein 1 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 |
| SMG9 | SMG9 nonsense mediated mRNA decay factor |
| SNHG3 | small nucleolar RNA host gene 3 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TARBP2 | TAR (HIV-1) RNA binding protein 2 |
| TMEM120B | transmembrane protein 120B |
| TMEM156 | transmembrane protein 156 |
| TRAPPC12 | trafficking protein particle complex 12 |
| TRIM9 | tripartite motif containing 9 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| USP20 | ubiquitin specific peptidase 20 |
| WFDC2 | WAP four-disulfide core domain 2 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZNF10 | zinc finger protein 10 |
| ZNF197 | zinc finger protein 197 |
| ZNF768 | zinc finger protein 768 |
| ZNF84 | zinc finger protein 84 |
| ZXDC | ZXD family zinc finger C |
