t cell costimulation Gene Set

Dataset GO Biological Process Annotations 2015
Category structural or functional annotations
Type biological process
Description The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation. (Gene Ontology, GO_0031295)
External Link http://amigo.geneontology.org/amigo/term/GO:0031295
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Genes

66 genes participating in the t cell costimulation biological process from the curated GO Biological Process Annotations 2015 dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
BTLA B and T lymphocyte associated
CARD11 caspase recruitment domain family, member 11
CAV1 caveolin 1, caveolae protein, 22kDa
CCL19 chemokine (C-C motif) ligand 19
CCL21 chemokine (C-C motif) ligand 21
CD24 CD24 molecule
CD247 CD247 molecule
CD274 CD274 molecule
CD28 CD28 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD4 CD4 molecule
CD5 CD5 molecule
CD80 CD80 molecule
CD86 CD86 molecule
CDC42 cell division cycle 42
CSK c-src tyrosine kinase
CTLA4 cytotoxic T-lymphocyte-associated protein 4
DPP4 dipeptidyl-peptidase 4
FYN FYN proto-oncogene, Src family tyrosine kinase
GRAP2 GRB2-related adaptor protein 2
GRB2 growth factor receptor-bound protein 2
HHLA2 HERV-H LTR-associating 2
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DQB2 major histocompatibility complex, class II, DQ beta 2
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-DRB4 major histocompatibility complex, class II, DR beta 4
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
ICOS inducible T-cell co-stimulator
LCK LCK proto-oncogene, Src family tyrosine kinase
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS8 lectin, galactoside-binding, soluble, 8
LYN LYN proto-oncogene, Src family tyrosine kinase
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPKAP1 mitogen-activated protein kinase associated protein 1
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PDCD1 programmed cell death 1
PDCD1LG2 programmed cell death 1 ligand 2
PDPK1 3-phosphoinositide dependent protein kinase 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN6 protein tyrosine phosphatase, non-receptor type 6
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RICTOR RPTOR independent companion of MTOR, complex 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
TMIGD2 transmembrane and immunoglobulin domain containing 2
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
VAV1 vav 1 guanine nucleotide exchange factor
YES1 YES proto-oncogene 1, Src family tyrosine kinase