t cell receptor complex Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains. (Gene Ontology, GO_0042101)
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11 proteins localized to the t cell receptor complex cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CD247 CD247 molecule 0.663342
CD4 CD4 molecule 0.663342
TRAT1 T cell receptor associated transmembrane adaptor 1 0.663342
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 0.663342
CD3G CD3g molecule, gamma (CD3-TCR complex) 0.663342
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.663342
CD3D CD3d molecule, delta (CD3-TCR complex) 0.663342
CD8B CD8b molecule 0.663342
CD8A CD8a molecule 0.663342
SYK spleen tyrosine kinase 0.663342
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.03318