t cell receptor complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains. (Gene Ontology, GO_0042101)
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186 proteins co-occuring with the t cell receptor complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CD4 CD4 molecule 2.83116
TRAC T cell receptor alpha constant 2.45626
GNG8 guanine nucleotide binding protein (G protein), gamma 8 1.88901
IL2 interleukin 2 1.80908
CD5 CD5 molecule 1.5656
CD3G CD3g molecule, gamma (CD3-TCR complex) 1.47683
HLA-B major histocompatibility complex, class I, B 1.41138
CD247 CD247 molecule 1.40019
THY1 Thy-1 cell surface antigen 1.34992
LCK LCK proto-oncogene, Src family tyrosine kinase 1.34338
CD3D CD3d molecule, delta (CD3-TCR complex) 1.26181
CD69 CD69 molecule 1.23818
CD48 CD48 molecule 1.22984
NT5C 5', 3'-nucleotidase, cytosolic 1.19777
IL2RA interleukin 2 receptor, alpha 1.17671
CTLA4 cytotoxic T-lymphocyte-associated protein 4 1.12347
CD44 CD44 molecule (Indian blood group) 1.04381
CD8B CD8b molecule 1.00695
SELL selectin L 1.00202
CD1D CD1d molecule 0.977589
NCAM1 neural cell adhesion molecule 1 0.954005
CD2 CD2 molecule 0.945432
HLA-A major histocompatibility complex, class I, A 0.927483
IL7 interleukin 7 0.917177
CD7 CD7 molecule 0.898572
KLRB1 killer cell lectin-like receptor subfamily B, member 1 0.88286
CDR1 cerebellar degeneration-related protein 1, 34kDa 0.875948
PTPRC protein tyrosine phosphatase, receptor type, C 0.849746
FYN FYN proto-oncogene, Src family tyrosine kinase 0.840105
RAG1 recombination activating gene 1 0.840105
RAG2 recombination activating gene 2 0.829089
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.828171
CD19 CD19 molecule 0.797436
KLRD1 killer cell lectin-like receptor subfamily D, member 1 0.789649
KLRK1 killer cell lectin-like receptor subfamily K, member 1 0.776384
KLRC2 killer cell lectin-like receptor subfamily C, member 2 0.772275
TRGV7 T cell receptor gamma variable 7 (pseudogene) 0.749999
TRGV3 T cell receptor gamma variable 3 0.749999
TRBV9 T cell receptor beta variable 9 0.749999
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.726599
CD1B CD1b molecule 0.718125
CD28 CD28 molecule 0.696465
PRF1 perforin 1 (pore forming protein) 0.682899
FOXP3 forkhead box P3 0.682027
IL4 interleukin 4 0.672894
AOC3 amine oxidase, copper containing 3 0.6638
HLA-E major histocompatibility complex, class I, E 0.660345
HLA-C major histocompatibility complex, class I, C 0.646145
ICAM1 intercellular adhesion molecule 1 0.63715
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.620954
CCL25 chemokine (C-C motif) ligand 25 0.609932
MICA MHC class I polypeptide-related sequence A 0.608241
B2M beta-2-microglobulin 0.60655
CD86 CD86 molecule 0.596855
TGFB1 transforming growth factor, beta 1 0.596014
CD79A CD79a molecule, immunoglobulin-associated alpha 0.583431
KLRC1 killer cell lectin-like receptor subfamily C, member 1 0.577581
CDR2 cerebellar degeneration-related protein 2, 62kDa 0.572578
CD6 CD6 molecule 0.562187
NCR1 natural cytotoxicity triggering receptor 1 0.553491
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.552251
CD80 CD80 molecule 0.524704
B3GAT1 beta-1,3-glucuronyltransferase 1 0.505537
IL7R interleukin 7 receptor 0.502288
KLRAP1 killer cell lectin-like receptor subfamily A pseudogene 1 0.487307
SKAP1 src kinase associated phosphoprotein 1 0.484079
MICB MHC class I polypeptide-related sequence B 0.480855
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.477636
CD27 CD27 molecule 0.450438
IL10 interleukin 10 0.445275
HIST1H2BE histone cluster 1, H2be 0.44052
HIST1H2BG histone cluster 1, H2bg 0.44052
HIST1H2BI histone cluster 1, H2bi 0.44052
FGF7 fibroblast growth factor 7 0.433801
CD276 CD276 molecule 0.432224
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.420428
FASLG Fas ligand (TNF superfamily, member 6) 0.415728
CD40LG CD40 ligand 0.410259
CD58 CD58 molecule 0.409479
PLCG1 phospholipase C, gamma 1 0.405582
CXCR5 chemokine (C-X-C motif) receptor 5 0.398975
CT45A1 cancer/testis antigen family 45, member A1 0.392388
HYI hydroxypyruvate isomerase (putative) 0.378122
CD38 CD38 molecule 0.355563
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.355563
DLL1 delta-like 1 (Drosophila) 0.354422
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.352901
CRTAM cytotoxic and regulatory T cell molecule 0.347208
PBX3 pre-B-cell leukemia homeobox 3 0.345314
TNF tumor necrosis factor 0.341529
TYROBP TYRO protein tyrosine kinase binding protein 0.327956
NOTCH1 notch 1 0.327956
MDFI MyoD family inhibitor 0.315586
CD320 CD320 molecule 0.314839
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.308122
NAT8 N-acetyltransferase 8 (GCN5-related, putative) 0.307377
LAG3 lymphocyte-activation gene 3 0.305515
GATA3 GATA binding protein 3 0.302912
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 0.301425
PTCRA pre T-cell antigen receptor alpha 0.299197
CD72 CD72 molecule 0.29586
KIR2DL1 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 0.295119
MYOM3 myomesin 3 0.293637
NDN necdin, melanoma antigen (MAGE) family member 0.286983
TCF12 transcription factor 12 0.282189
HAUS3 HAUS augmin-like complex, subunit 3 0.282189
HOXB3 homeobox B3 0.281453
WDR48 WD repeat domain 48 0.277406
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.273367
CCL5 chemokine (C-C motif) ligand 5 0.271167
MBP myelin basic protein 0.270434
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.267139
HEBP2 heme binding protein 2 0.264215
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.26385
IGHV3-30 immunoglobulin heavy variable 3-30 0.26385
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.26239
SBF1 SET binding factor 1 0.261296
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa 0.257289
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3 0.250026
CNST consortin, connexin sorting protein 0.249664
STAT5A signal transducer and activator of transcription 5A 0.246769
FYB FYN binding protein 0.238119
STAT5B signal transducer and activator of transcription 5B 0.23776
TBX21 T-box 21 0.235607
JCHAIN joining chain of multimeric IgA and IgM 0.235607
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.227041
PRAME preferentially expressed antigen in melanoma 0.226686
CD160 CD160 molecule 0.224558
MRAP melanocortin 2 receptor accessory protein 0.221378
ERCC6 excision repair cross-complementation group 6 0.221025
SLAMF6 SLAM family member 6 0.220321
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.216111
CCR6 chemokine (C-C motif) receptor 6 0.210203
IL1A interleukin 1, alpha 0.208481
PLXND1 plexin D1 0.207451
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.206766
NELFCD negative elongation factor complex member C/D 0.203022
DPT dermatopontin 0.200663
IL17A interleukin 17A 0.198658
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 0.197662
ITK IL2-inducible T-cell kinase 0.196339
IL5 interleukin 5 0.195353
DHDH dihydrodiol dehydrogenase (dimeric) 0.185469
CD33 CD33 molecule 0.18516
DNTT DNA nucleotidylexotransferase 0.183631
IFNA1 interferon, alpha 1 0.181823
GNLY granulysin 0.179167
MAGEA4 melanoma antigen family A4 0.178011
BTLA B and T lymphocyte associated 0.175745
CCL3 chemokine (C-C motif) ligand 3 0.171149
CD34 CD34 molecule 0.170888
CD1C CD1c molecule 0.170114
MOG myelin oligodendrocyte glycoprotein 0.169859
SELE selectin E 0.168101
CXCL10 chemokine (C-X-C motif) ligand 10 0.165463
PBX2 pre-B-cell leukemia homeobox 2 0.161484
FGL2 fibrinogen-like 2 0.160863
AMH anti-Mullerian hormone 0.160254
FABP2 fatty acid binding protein 2, intestinal 0.144409
KIR2DL2 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 2 0.143538
PCYT1A phosphate cytidylyltransferase 1, choline, alpha 0.141706
KIR3DL1 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1 0.141653
CD8A CD8a molecule 0.141497
CD200R1 CD200 receptor 1 0.135192
RP9 retinitis pigmentosa 9 (autosomal dominant) 0.134718
MEGF6 multiple EGF-like-domains 6 0.134131
PHB2 prohibitin 2 0.133303
JAK3 Janus kinase 3 0.133233
DLK1 delta-like 1 homolog (Drosophila) 0.133177
LAT linker for activation of T cells 0.132598
LAT2 linker for activation of T cells family, member 2 0.132433
IGHV3-9 immunoglobulin heavy variable 3-9 0.13225
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.132173
LTA lymphotoxin alpha 0.13208
LGALS7B lectin, galactoside-binding, soluble, 7B 0.132033
KIR3DL2 killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2 0.131568
RAE1 ribonucleic acid export 1 0.131099
PTEN phosphatase and tensin homolog 0.130716
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.130338
CCR7 chemokine (C-C motif) receptor 7 0.130191
CLMP CXADR-like membrane protein 0.130173
C5 complement component 5 0.129621
SIGLEC10 sialic acid binding Ig-like lectin 10 0.129164
MAGEA3 melanoma antigen family A3 0.128918
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.128366
CD200 CD200 molecule 0.12819