t cell receptor signaling pathway Gene Set

Dataset Biocarta Pathways
Category structural or functional annotations
Type pathway
Description A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell. (Gene Ontology, GO_0050852)
External Link http://cgap.nci.nih.gov/Pathways/BioCarta/h_tcrPathway
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Genes

55 proteins participating in the t cell receptor signaling pathway pathway from the Biocarta Pathways dataset.

Symbol Name
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
ARFGAP3 ADP-ribosylation factor GTPase activating protein 3
ARHGAP1 Rho GTPase activating protein 1
ARHGAP4 Rho GTPase activating protein 4
ARHGAP5 Rho GTPase activating protein 5
ARHGAP6 Rho GTPase activating protein 6
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CD247 CD247 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CD3E CD3e molecule, epsilon (CD3-TCR complex)
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD4 CD4 molecule
CHN1 chimerin 1
ELK1 ELK1, member of ETS oncogene family
FOS FBJ murine osteosarcoma viral oncogene homolog
FYN FYN proto-oncogene, Src family tyrosine kinase
GRB2 growth factor receptor-bound protein 2
HLA-DRA major histocompatibility complex, class II, DR alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HRAS Harvey rat sarcoma viral oncogene homolog
JUN jun proto-oncogene
LAT linker for activation of T cells
LCK LCK proto-oncogene, Src family tyrosine kinase
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
NCF2 neutrophil cytosolic factor 2
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PLCG1 phospholipase C, gamma 1
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PPP3CC protein phosphatase 3, catalytic subunit, gamma isozyme
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PTPN7 protein tyrosine phosphatase, non-receptor type 7
PTPRC protein tyrosine phosphatase, receptor type, C
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RALBP1 ralA binding protein 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SOS1 son of sevenless homolog 1 (Drosophila)
TRA T cell receptor alpha locus
TRB T cell receptor beta locus
VAV1 vav 1 guanine nucleotide exchange factor
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa