tRNA aminoacylation Gene Set
Dataset
GO Biological Process Annotations 2025
Category
structural or functional annotations
Type
biological process
Description
The chemical reactions and pathways by which the various amino acids become bonded to their corresponding tRNAs. The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules. (Gene Ontology , GO_0043039 )
External Link
http://amigo.geneontology.org/amigo/term/GO:0043039
Similar Terms
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Genes
23 genes participating in the tRNA aminoacylation biological process from the curated GO Biological Process Annotations 2025 dataset.
Symbol
Name
AARS1
alanyl-tRNA synthetase 1
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
DTD1
D-tyrosyl-tRNA deacylase 1
EPRS1
glutamyl-prolyl-tRNA synthetase 1
FARS2
phenylalanyl-tRNA synthetase 2, mitochondrial
GARS1
glycyl-tRNA synthetase 1
GATB
glutamyl-tRNA(Gln) amidotransferase, subunit B
GATC
glutamyl-tRNA(Gln) amidotransferase, subunit C
HARS1
histidyl-tRNA synthetase 1
IARS1
isoleucyl-tRNA synthetase 1
IARS2
isoleucyl-tRNA synthetase 2, mitochondrial
LARS1
leucyl-tRNA synthetase 1
LARS2
leucyl-tRNA synthetase 2, mitochondrial
MARS1
methionyl-tRNA synthetase 1
MARS2
methionyl-tRNA synthetase 2, mitochondrial
NARS1
asparaginyl-tRNA synthetase 1
QARS1
glutaminyl-tRNA synthetase 1
QRSL1
glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
RARS1
arginyl-tRNA synthetase 1
RARS2
arginyl-tRNA synthetase 2, mitochondrial
VARS1
valyl-tRNA synthetase 1
WARS2
tryptophanyl tRNA synthetase 2, mitochondrial
YARS2
tyrosyl-tRNA synthetase 2, mitochondrial
