| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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191 genes differentially expressed following the tacrine-5297 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAR2 | AAR2 splicing factor homolog (S. cerevisiae) |
| ADAP1 | ArfGAP with dual PH domains 1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| AREG | amphiregulin |
| ARTN | artemin |
| AXIN1 | axin 1 |
| BCL2L1 | BCL2-like 1 |
| BMP1 | bone morphogenetic protein 1 |
| CABIN1 | calcineurin binding protein 1 |
| CDK17 | cyclin-dependent kinase 17 |
| CHKB | choline kinase beta |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CLEC11A | C-type lectin domain family 11, member A |
| CLGN | calmegin |
| CTTN | cortactin |
| DDX11 | DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 |
| DUSP4 | dual specificity phosphatase 4 |
| DYNC2LI1 | dynein, cytoplasmic 2, light intermediate chain 1 |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| EGR1 | early growth response 1 |
| EGR3 | early growth response 3 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 |
| EPHA2 | EPH receptor A2 |
| ETV5 | ets variant 5 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FOSL1 | FOS-like antigen 1 |
| G6PC3 | glucose 6 phosphatase, catalytic, 3 |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIH1 | interferon induced with helicase C domain 1 |
| IFITM1 | interferon induced transmembrane protein 1 |
| INADL | InaD-like (Drosophila) |
| INHBB | inhibin, beta B |
| ISG15 | ISG15 ubiquitin-like modifier |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIAA0485 | uncharacterized LOC57235 |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLHL25 | kelch-like family member 25 |
| LAD1 | ladinin 1 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MINOS1P1 | mitochondrial inner membrane organizing system 1 pseudogene 1 |
| NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase |
| NAV2 | neuron navigator 2 |
| NCKAP1 | NCK-associated protein 1 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NR2F6 | nuclear receptor subfamily 2, group F, member 6 |
| OPN3 | opsin 3 |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PCDHB3 | protocadherin beta 3 |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
| QKI | QKI, KH domain containing, RNA binding |
| QPRT | quinolinate phosphoribosyltransferase |
| RAB6A | RAB6A, member RAS oncogene family |
| RALB | v-ral simian leukemia viral oncogene homolog B |
| RANBP1 | RAN binding protein 1 |
| RNF19B | ring finger protein 19B |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPS28 | ribosomal protein S28 |
| RPS9 | ribosomal protein S9 |
| S100A4 | S100 calcium binding protein A4 |
| SEMA3F | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SGSM3 | small G protein signaling modulator 3 |
| SH2D4A | SH2 domain containing 4A |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SMAD3 | SMAD family member 3 |
| SPAG1 | sperm associated antigen 1 |
| SUPT7L | suppressor of Ty 7 (S. cerevisiae)-like |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
| TLE3 | transducin-like enhancer of split 3 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) |
| TRIM44 | tripartite motif containing 44 |
| TRIM66 | tripartite motif containing 66 |
| TUBGCP2 | tubulin, gamma complex associated protein 2 |
| UBQLN4 | ubiquilin 4 |
| URB2 | URB2 ribosome biogenesis 2 homolog (S. cerevisiae) |
| WNK1 | WNK lysine deficient protein kinase 1 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF365 | zinc finger protein 365 |
| ZNF467 | zinc finger protein 467 |
| ZNF821 | zinc finger protein 821 |
| ZW10 | zw10 kinetochore protein |
| Symbol | Name |
|---|---|
| ABHD14A | abhydrolase domain containing 14A |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ANXA2P3 | annexin A2 pseudogene 3 |
| APOD | apolipoprotein D |
| ARMC6 | armadillo repeat containing 6 |
| ARRB2 | arrestin, beta 2 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| BBS10 | Bardet-Biedl syndrome 10 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C19ORF40 | chromosome 19 open reading frame 40 |
| CBY1 | chibby homolog 1 (Drosophila) |
| CCDC25 | coiled-coil domain containing 25 |
| CCDC94 | coiled-coil domain containing 94 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| CNN2 | calponin 2 |
| CPSF7 | cleavage and polyadenylation specific factor 7, 59kDa |
| CSNK1E | casein kinase 1, epsilon |
| CTSK | cathepsin K |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| FYCO1 | FYVE and coiled-coil domain containing 1 |
| GAB2 | GRB2-associated binding protein 2 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2BI | histone cluster 1, H2bi |
| HIST1H2BO | histone cluster 1, H2bo |
| HIST1H3B | histone cluster 1, H3b |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| IFT81 | intraflagellar transport 81 |
| IL17RB | interleukin 17 receptor B |
| JRKL | JRK-like |
| KIF13B | kinesin family member 13B |
| KPTN | kaptin (actin binding protein) |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LMBR1L | limb development membrane protein 1-like |
| LMNB1 | lamin B1 |
| LOC730101 | uncharacterized LOC730101 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MBTD1 | mbt domain containing 1 |
| MED9 | mediator complex subunit 9 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| OCEL1 | occludin/ELL domain containing 1 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRPH | peripherin |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RFTN1 | raftlin, lipid raft linker 1 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RIN2 | Ras and Rab interactor 2 |
| SIL1 | SIL1 nucleotide exchange factor |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SMA4 | glucuronidase, beta pseudogene |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| STK16 | serine/threonine kinase 16 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| SUSD6 | sushi domain containing 6 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TET3 | tet methylcytosine dioxygenase 3 |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TPCN1 | two pore segment channel 1 |
| TRAF2 | TNF receptor-associated factor 2 |
| TSPYL2 | TSPY-like 2 |
| TTC4 | tetratricopeptide repeat domain 4 |
| TUBA3C | tubulin, alpha 3c |
| UNC119 | unc-119 homolog (C. elegans) |
| USP20 | ubiquitin specific peptidase 20 |
| VGF | VGF nerve growth factor inducible |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZIC1 | Zic family member 1 |
| ZNF282 | zinc finger protein 282 |
| ZNF639 | zinc finger protein 639 |
| ZNF816 | zinc finger protein 816 |
| ZNF862 | zinc finger protein 862 |
| ZSCAN5A | zinc finger and SCAN domain containing 5A |
