| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the tacrine-6698 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACOT11 | acyl-CoA thioesterase 11 |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADD2 | adducin 2 (beta) |
| ADTRP | androgen-dependent TFPI-regulating protein |
| AHNAK | AHNAK nucleoprotein |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ALOX12B | arachidonate 12-lipoxygenase, 12R type |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BGN | biglycan |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CAMK1G | calcium/calmodulin-dependent protein kinase IG |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CASS4 | Cas scaffolding protein family member 4 |
| CCL23 | chemokine (C-C motif) ligand 23 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) |
| COMP | cartilage oligomeric matrix protein |
| COMT | catechol-O-methyltransferase |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| CTSE | cathepsin E |
| DCLK2 | doublecortin-like kinase 2 |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
| DKFZP434C153 | DKFZP434C153 protein |
| DZIP1 | DAZ interacting zinc finger protein 1 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 |
| EFCAB11 | EF-hand calcium binding domain 11 |
| ELAC1 | elaC ribonuclease Z 1 |
| ESR1 | estrogen receptor 1 |
| FLT3LG | fms-related tyrosine kinase 3 ligand |
| GABRA6 | gamma-aminobutyric acid (GABA) A receptor, alpha 6 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GAS8 | growth arrest-specific 8 |
| GLP1R | glucagon-like peptide 1 receptor |
| GPR75 | G protein-coupled receptor 75 |
| GRM8 | glutamate receptor, metabotropic 8 |
| GYG2 | glycogenin 2 |
| HAPLN1 | hyaluronan and proteoglycan link protein 1 |
| HDAC6 | histone deacetylase 6 |
| HEG1 | heart development protein with EGF-like domains 1 |
| HIST1H4D | histone cluster 1, H4d |
| ICAM1 | intercellular adhesion molecule 1 |
| ITGA7 | integrin, alpha 7 |
| KLF4 | Kruppel-like factor 4 (gut) |
| KNG1 | kininogen 1 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 |
| MDM4 | MDM4, p53 regulator |
| MEFV | Mediterranean fever |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MTCP1 | mature T-cell proliferation 1 |
| OGFR | opioid growth factor receptor |
| OMG | oligodendrocyte myelin glycoprotein |
| PATZ1 | POZ (BTB) and AT hook containing zinc finger 1 |
| PAX2 | paired box 2 |
| PCDHA5 | protocadherin alpha 5 |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PITX2 | paired-like homeodomain 2 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) |
| PRKG1 | protein kinase, cGMP-dependent, type I |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PRO2964 | uncharacterized protein PRO2964 |
| RAB31 | RAB31, member RAS oncogene family |
| RAB6A | RAB6A, member RAS oncogene family |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RARG | retinoic acid receptor, gamma |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RBM12B-AS1 | RBM12B antisense RNA 1 |
| RGS12 | regulator of G-protein signaling 12 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| RUNX1 | runt-related transcription factor 1 |
| SETD1A | SET domain containing 1A |
| SH2D4A | SH2 domain containing 4A |
| SIRPA | signal-regulatory protein alpha |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SOX21 | SRY (sex determining region Y)-box 21 |
| SPTB | spectrin, beta, erythrocytic |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
| STMN2 | stathmin 2 |
| SYT2 | synaptotagmin II |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TAPT1 | transmembrane anterior posterior transformation 1 |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRIM3 | tripartite motif containing 3 |
| TUBA3C | tubulin, alpha 3c |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| YTHDC2 | YTH domain containing 2 |
| YY1 | YY1 transcription factor |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF589 | zinc finger protein 589 |
| ZNF609 | zinc finger protein 609 |
| Symbol | Name |
|---|---|
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ANOS1 | anosmin 1 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARHGEF26 | Rho guanine nucleotide exchange factor (GEF) 26 |
| ARL14 | ADP-ribosylation factor-like 14 |
| ARMCX2 | armadillo repeat containing, X-linked 2 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C1ORF27 | chromosome 1 open reading frame 27 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CXORF56 | chromosome X open reading frame 56 |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DAGLA | diacylglycerol lipase, alpha |
| DDN | dendrin |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| ELOVL6 | ELOVL fatty acid elongase 6 |
| ERCC5 | excision repair cross-complementation group 5 |
| FA2H | fatty acid 2-hydroxylase |
| FAM186A | family with sequence similarity 186, member A |
| FAM188A | family with sequence similarity 188, member A |
| FBRS | fibrosin |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GSTA3 | glutathione S-transferase alpha 3 |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| IER3IP1 | immediate early response 3 interacting protein 1 |
| IL36RN | interleukin 36 receptor antagonist |
| KDM8 | lysine (K)-specific demethylase 8 |
| KIAA1456 | KIAA1456 |
| KLHDC4 | kelch domain containing 4 |
| KRT4 | keratin 4, type II |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LMO7 | LIM domain 7 |
| LOC100287590 | uncharacterized LOC100287590 |
| LOC202181 | SUMO-interacting motifs containing 1 pseudogene |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LRRC6 | leucine rich repeat containing 6 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAPK12 | mitogen-activated protein kinase 12 |
| METTL1 | methyltransferase like 1 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MOCS1 | molybdenum cofactor synthesis 1 |
| MPC1 | mitochondrial pyruvate carrier 1 |
| MYH15 | myosin, heavy chain 15 |
| NAALAD2 | N-acetylated alpha-linked acidic dipeptidase 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NXPH4 | neurexophilin 4 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PDE8B | phosphodiesterase 8B |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PMCH | pro-melanin-concentrating hormone |
| PRR15L | proline rich 15-like |
| PRSS22 | protease, serine, 22 |
| QSER1 | glutamine and serine rich 1 |
| RAB33B | RAB33B, member RAS oncogene family |
| RAI2 | retinoic acid induced 2 |
| RAPSN | receptor-associated protein of the synapse |
| RGCC | regulator of cell cycle |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RUFY2 | RUN and FYVE domain containing 2 |
| SCAI | suppressor of cancer cell invasion |
| SCARA3 | scavenger receptor class A, member 3 |
| SECISBP2 | SECIS binding protein 2 |
| SLC18A2 | solute carrier family 18 (vesicular monoamine transporter), member 2 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SOBP | sine oculis binding protein homolog (Drosophila) |
| SPATA2L | spermatogenesis associated 2-like |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| TGS1 | trimethylguanosine synthase 1 |
| TMEM121 | transmembrane protein 121 |
| TMEM177 | transmembrane protein 177 |
| TSC22D4 | TSC22 domain family, member 4 |
| VSIG10 | V-set and immunoglobulin domain containing 10 |
| WDR25 | WD repeat domain 25 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| ZBTB33 | zinc finger and BTB domain containing 33 |
| ZNF10 | zinc finger protein 10 |
| ZNF141 | zinc finger protein 141 |
| ZNF205 | zinc finger protein 205 |
| ZNF442 | zinc finger protein 442 |
| ZNF671 | zinc finger protein 671 |
| ZNF770 | zinc finger protein 770 |
