| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the tacrolimus-169 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARHGAP32 | Rho GTPase activating protein 32 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase |
| B3GAT3 | beta-1,3-glucuronyltransferase 3 |
| B4GALT7 | xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 |
| BACE1 | beta-site APP-cleaving enzyme 1 |
| BECN1 | beclin 1, autophagy related |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| C2CD2L | C2CD2-like |
| CA14 | carbonic anhydrase XIV |
| CA4 | carbonic anhydrase IV |
| CBX8 | chromobox homolog 8 |
| CCNT2 | cyclin T2 |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) |
| CEP57 | centrosomal protein 57kDa |
| CES3 | carboxylesterase 3 |
| CLEC11A | C-type lectin domain family 11, member A |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| COMMD8 | COMM domain containing 8 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 |
| CYP4A11 | cytochrome P450, family 4, subfamily A, polypeptide 11 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 |
| DENND3 | DENN/MADD domain containing 3 |
| DIEXF | digestive organ expansion factor homolog (zebrafish) |
| DNAH3 | dynein, axonemal, heavy chain 3 |
| DRP2 | dystrophin related protein 2 |
| DVL3 | dishevelled segment polarity protein 3 |
| FN1 | fibronectin 1 |
| FNDC3A | fibronectin type III domain containing 3A |
| GALR3 | galanin receptor 3 |
| GFOD2 | glucose-fructose oxidoreductase domain containing 2 |
| GNRH2 | gonadotropin-releasing hormone 2 |
| GOLPH3L | golgi phosphoprotein 3-like |
| GRK5 | G protein-coupled receptor kinase 5 |
| GSTM4 | glutathione S-transferase mu 4 |
| GTPBP1 | GTP binding protein 1 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 |
| IL2RA | interleukin 2 receptor, alpha |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KIAA0368 | KIAA0368 |
| KIAA0391 | KIAA0391 |
| KIF1C | kinesin family member 1C |
| KLF12 | Kruppel-like factor 12 |
| KLHL9 | kelch-like family member 9 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| KRT2 | keratin 2, type II |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| MBD1 | methyl-CpG binding domain protein 1 |
| MC2R | melanocortin 2 receptor (adrenocorticotropic hormone) |
| MED14 | mediator complex subunit 14 |
| MMP19 | matrix metallopeptidase 19 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MYOZ1 | myozenin 1 |
| NOC4L | nucleolar complex associated 4 homolog (S. cerevisiae) |
| OPTN | optineurin |
| PCNP | PEST proteolytic signal containing nuclear protein |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited |
| PDE6D | phosphodiesterase 6D, cGMP-specific, rod, delta |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 |
| PRDM14 | PR domain containing 14 |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| PSIP1 | PC4 and SFRS1 interacting protein 1 |
| PTCRA | pre T-cell antigen receptor alpha |
| PTK2B | protein tyrosine kinase 2 beta |
| RAD1 | RAD1 checkpoint DNA exonuclease |
| RCAN1 | regulator of calcineurin 1 |
| RGS3 | regulator of G-protein signaling 3 |
| RPLP2 | ribosomal protein, large, P2 |
| RPS2 | ribosomal protein S2 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| RUNDC3A | RUN domain containing 3A |
| SERBP1 | SERPINE1 mRNA binding protein 1 |
| SLC25A40 | solute carrier family 25, member 40 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SNHG20 | small nucleolar RNA host gene 20 |
| SPN | sialophorin |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SRCAP | Snf2-related CREBBP activator protein |
| SSTR4 | somatostatin receptor 4 |
| SYF2 | SYF2 pre-mRNA-splicing factor |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) |
| TBRG4 | transforming growth factor beta regulator 4 |
| TEAD4 | TEA domain family member 4 |
| TMEM115 | transmembrane protein 115 |
| TRIM62 | tripartite motif containing 62 |
| TUBD1 | tubulin, delta 1 |
| UBE3A | ubiquitin protein ligase E3A |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| Symbol | Name |
|---|---|
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 |
| ACBD4 | acyl-CoA binding domain containing 4 |
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADORA3 | adenosine A3 receptor |
| AQP8 | aquaporin 8 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
| ATP11B | ATPase, class VI, type 11B |
| BAP1 | BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) |
| BCAS1 | breast carcinoma amplified sequence 1 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C2 | complement component 2 |
| CARD8 | caspase recruitment domain family, member 8 |
| CARM1 | coactivator-associated arginine methyltransferase 1 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCS | copper chaperone for superoxide dismutase |
| CD8A | CD8a molecule |
| CDK18 | cyclin-dependent kinase 18 |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CEBPE | CCAAT/enhancer binding protein (C/EBP), epsilon |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLPS | colipase, pancreatic |
| CNTD2 | cyclin N-terminal domain containing 2 |
| COBL | cordon-bleu WH2 repeat protein |
| CXORF56 | chromosome X open reading frame 56 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DEFA5 | defensin, alpha 5, Paneth cell-specific |
| DMTN | dematin actin binding protein |
| DUSP13 | dual specificity phosphatase 13 |
| ECHDC1 | ethylmalonyl-CoA decarboxylase 1 |
| EPN1 | epsin 1 |
| EXOC2 | exocyst complex component 2 |
| FA2H | fatty acid 2-hydroxylase |
| FAM153A | family with sequence similarity 153, member A |
| FAM198B | family with sequence similarity 198, member B |
| FAM222B | family with sequence similarity 222, member B |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FRMD8 | FERM domain containing 8 |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| GRAMD1B | GRAM domain containing 1B |
| GRIP2 | glutamate receptor interacting protein 2 |
| HDAC7 | histone deacetylase 7 |
| HELLS | helicase, lymphoid-specific |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| LHX3 | LIM homeobox 3 |
| LIAS | lipoic acid synthetase |
| LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| LY86 | lymphocyte antigen 86 |
| MAS1 | MAS1 proto-oncogene, G protein-coupled receptor |
| MFAP2 | microfibrillar-associated protein 2 |
| MPPED1 | metallophosphoesterase domain containing 1 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NPY | neuropeptide Y |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| OMG | oligodendrocyte myelin glycoprotein |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PARG | poly (ADP-ribose) glycohydrolase |
| PGS1 | phosphatidylglycerophosphate synthase 1 |
| PKD2L1 | polycystic kidney disease 2-like 1 |
| POGLUT1 | protein O-glucosyltransferase 1 |
| PQLC2 | PQ loop repeat containing 2 |
| PRKCE | protein kinase C, epsilon |
| RAB4B | RAB4B, member RAS oncogene family |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RIN1 | Ras and Rab interactor 1 |
| RLBP1 | retinaldehyde binding protein 1 |
| S1PR4 | sphingosine-1-phosphate receptor 4 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SCN10A | sodium channel, voltage gated, type X alpha subunit |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SH2B3 | SH2B adaptor protein 3 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SSFA2 | sperm specific antigen 2 |
| STARD8 | StAR-related lipid transfer (START) domain containing 8 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| T | T, brachyury homolog (mouse) |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 |
| TCEAL1 | transcription elongation factor A (SII)-like 1 |
| TCTN1 | tectonic family member 1 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TMEM51 | transmembrane protein 51 |
| TUBA4B | tubulin, alpha 4b |
| TWF2 | twinfilin actin binding protein 2 |
| UBTD1 | ubiquitin domain containing 1 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WASF1 | WAS protein family, member 1 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
