| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the tacrolimus-284 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABR | active BCR-related |
| ADGRG1 | adhesion G protein-coupled receptor G1 |
| AGRN | agrin |
| ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| ATG13 | autophagy related 13 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| AXIN1 | axin 1 |
| BICD2 | bicaudal D homolog 2 (Drosophila) |
| BRD2 | bromodomain containing 2 |
| BTBD2 | BTB (POZ) domain containing 2 |
| C16ORF58 | chromosome 16 open reading frame 58 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C2CD2L | C2CD2-like |
| C9ORF156 | chromosome 9 open reading frame 156 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CALM3 | calmodulin 3 (phosphorylase kinase, delta) |
| CALR | calreticulin |
| CALU | calumenin |
| CDK10 | cyclin-dependent kinase 10 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| COBL | cordon-bleu WH2 repeat protein |
| CPD | carboxypeptidase D |
| CPTP | ceramide-1-phosphate transfer protein |
| DAXX | death-domain associated protein |
| DHPS | deoxyhypusine synthase |
| DST | dystonin |
| FAHD2A | fumarylacetoacetate hydrolase domain containing 2A |
| FAM192A | family with sequence similarity 192, member A |
| FCMR | Fc fragment of IgM receptor |
| FKBP8 | FK506 binding protein 8, 38kDa |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GRAMD3 | GRAM domain containing 3 |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) |
| HLA-E | major histocompatibility complex, class I, E |
| IGF2R | insulin-like growth factor 2 receptor |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| ING1 | inhibitor of growth family, member 1 |
| JMJD4 | jumonji domain containing 4 |
| KCTD13 | potassium channel tetramerization domain containing 13 |
| KIR2DL3 | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3 |
| LUZP1 | leucine zipper protein 1 |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 |
| MBD1 | methyl-CpG binding domain protein 1 |
| MZF1 | myeloid zinc finger 1 |
| NAGA | N-acetylgalactosaminidase, alpha- |
| NBEAL2 | neurobeachin-like 2 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NPR2 | natriuretic peptide receptor 2 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 |
| NUP210 | nucleoporin 210kDa |
| NXT2 | nuclear transport factor 2-like export factor 2 |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PGP | phosphoglycolate phosphatase |
| PHKA2 | phosphorylase kinase, alpha 2 (liver) |
| PHOX2A | paired-like homeobox 2a |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PLCD1 | phospholipase C, delta 1 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 |
| PPP2R4 | protein phosphatase 2A activator, regulatory subunit 4 |
| PRKCD | protein kinase C, delta |
| PRRC2A | proline-rich coiled-coil 2A |
| PXN | paxillin |
| RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
| RARA | retinoic acid receptor, alpha |
| RNF185 | ring finger protein 185 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SCIN | scinderin |
| SGSH | N-sulfoglucosamine sulfohydrolase |
| SH3BP2 | SH3-domain binding protein 2 |
| SMAD3 | SMAD family member 3 |
| SPG7 | spastic paraplegia 7 (pure and complicated autosomal recessive) |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) |
| TCF3 | transcription factor 3 |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRAF3 | TNF receptor-associated factor 3 |
| TRAPPC12 | trafficking protein particle complex 12 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TTLL4 | tubulin tyrosine ligase-like family member 4 |
| UBE4B | ubiquitination factor E4B |
| VAV2 | vav 2 guanine nucleotide exchange factor |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF408 | zinc finger protein 408 |
| ZNF580 | zinc finger protein 580 |
| Symbol | Name |
|---|---|
| ADAM30 | ADAM metallopeptidase domain 30 |
| ALX3 | ALX homeobox 3 |
| AMN | amnion associated transmembrane protein |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| ARHGAP24 | Rho GTPase activating protein 24 |
| ATF3 | activating transcription factor 3 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CAV3 | caveolin 3 |
| CCDC176 | coiled-coil domain containing 176 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHD2 | chromodomain helicase DNA binding protein 2 |
| CPN2 | carboxypeptidase N, polypeptide 2 |
| CRYAB | crystallin, alpha B |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 |
| CXORF21 | chromosome X open reading frame 21 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DMTN | dematin actin binding protein |
| DYSF | dysferlin |
| FKBP6 | FK506 binding protein 6, 36kDa |
| FLJ11710 | uncharacterized protein FLJ11710 |
| GDF10 | growth differentiation factor 10 |
| GP1BA | glycoprotein Ib (platelet), alpha polypeptide |
| GPR182 | G protein-coupled receptor 182 |
| GPR35 | G protein-coupled receptor 35 |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| HIST1H4E | histone cluster 1, H4e |
| HIST1H4J | histone cluster 1, H4j |
| HLA-DQB2 | major histocompatibility complex, class II, DQ beta 2 |
| HSD17B3 | hydroxysteroid (17-beta) dehydrogenase 3 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| INE1 | inactivation escape 1 (non-protein coding) |
| JMJD1C | jumonji domain containing 1C |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KIAA1324 | KIAA1324 |
| KIR2DL5A | killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A |
| KLK5 | kallikrein-related peptidase 5 |
| KRT23 | keratin 23, type I |
| KRT8P12 | keratin 8 pseudogene 12 |
| LEFTY2 | left-right determination factor 2 |
| LINC00574 | long intergenic non-protein coding RNA 574 |
| LMTK1 | lemur tail kinase 1 |
| LSM1 | LSM1, U6 small nuclear RNA associated |
| MAGOHB | mago-nashi homolog B (Drosophila) |
| MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| NDUFA1 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa |
| NEUROD4 | neuronal differentiation 4 |
| NEUROD6 | neuronal differentiation 6 |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NLRX1 | NLR family member X1 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| ONECUT2 | one cut homeobox 2 |
| OR3A3 | olfactory receptor, family 3, subfamily A, member 3 |
| PAQR6 | progestin and adipoQ receptor family member VI |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PGC | progastricsin (pepsinogen C) |
| PLA2G2F | phospholipase A2, group IIF |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PNOC | prepronociceptin |
| PNPLA6 | patatin-like phospholipase domain containing 6 |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PQLC2 | PQ loop repeat containing 2 |
| PRAME | preferentially expressed antigen in melanoma |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PSAT1 | phosphoserine aminotransferase 1 |
| RCVRN | recoverin |
| RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) |
| ROBO4 | roundabout, axon guidance receptor, homolog 4 (Drosophila) |
| RPL10L | ribosomal protein L10-like |
| RPL39L | ribosomal protein L39-like |
| S100A1 | S100 calcium binding protein A1 |
| SLC4A5 | solute carrier family 4 (sodium bicarbonate cotransporter), member 5 |
| SLC6A13 | solute carrier family 6 (neurotransmitter transporter), member 13 |
| SNTA1 | syntrophin, alpha 1 |
| SPON2 | spondin 2, extracellular matrix protein |
| STAT5A | signal transducer and activator of transcription 5A |
| STMN4 | stathmin-like 4 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) |
| TTTY15 | testis-specific transcript, Y-linked 15 (non-protein coding) |
| TUBA4A | tubulin, alpha 4a |
| VENTX | VENT homeobox |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| WNT7A | wingless-type MMTV integration site family, member 7A |
| ZNF124 | zinc finger protein 124 |