| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
195 genes differentially expressed following the tacrolimus-378 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADM2 | adrenomedullin 2 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ANKRD40 | ankyrin repeat domain 40 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| BCLAF1 | BCL2-associated transcription factor 1 |
| BTN2A1 | butyrophilin, subfamily 2, member A1 |
| C2CD2L | C2CD2-like |
| C7ORF26 | chromosome 7 open reading frame 26 |
| CACTIN | cactin, spliceosome C complex subunit |
| CAV3 | caveolin 3 |
| CD82 | CD82 molecule |
| CLIC5 | chloride intracellular channel 5 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CTNS | cystinosin, lysosomal cystine transporter |
| CYB5R2 | cytochrome b5 reductase 2 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DERL1 | derlin 1 |
| DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 |
| DUS2 | dihydrouridine synthase 2 |
| DXO | decapping exoribonuclease |
| EFCAB1 | EF-hand calcium binding domain 1 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| F12 | coagulation factor XII (Hageman factor) |
| FASTK | Fas-activated serine/threonine kinase |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GLG1 | golgi glycoprotein 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC5 | histone deacetylase 5 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 |
| IFITM2 | interferon induced transmembrane protein 2 |
| IRGQ | immunity-related GTPase family, Q |
| KLF2 | Kruppel-like factor 2 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LOC729164 | hCG1732469 |
| LPPR2 | lipid phosphate phosphatase-related protein type 2 |
| MAP2K2 | mitogen-activated protein kinase kinase 2 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MED6 | mediator complex subunit 6 |
| MEGF6 | multiple EGF-like-domains 6 |
| MRPS12 | mitochondrial ribosomal protein S12 |
| MRPS14 | mitochondrial ribosomal protein S14 |
| MST1 | macrophage stimulating 1 |
| MT1HL1 | metallothionein 1H-like 1 |
| NACAP1 | nascent-polypeptide-associated complex alpha polypeptide pseudogene 1 |
| NDRG3 | NDRG family member 3 |
| NDUFAF4 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 |
| NIPBL | Nipped-B homolog (Drosophila) |
| NMT1 | N-myristoyltransferase 1 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 |
| NSFL1C | NSFL1 (p97) cofactor (p47) |
| ORC4 | origin recognition complex, subunit 4 |
| PAFAH1B3 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PHOX2A | paired-like homeobox 2a |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PLEKHG3 | pleckstrin homology domain containing, family G (with RhoGef domain) member 3 |
| PLK4 | polo-like kinase 4 |
| POLM | polymerase (DNA directed), mu |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPME1 | protein phosphatase methylesterase 1 |
| PPP4C | protein phosphatase 4, catalytic subunit |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) |
| PSG9 | pregnancy specific beta-1-glycoprotein 9 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 |
| RAB1B | RAB1B, member RAS oncogene family |
| RAD1 | RAD1 checkpoint DNA exonuclease |
| RGS14 | regulator of G-protein signaling 14 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| RPS2 | ribosomal protein S2 |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| SATB1 | SATB homeobox 1 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SELPLG | selectin P ligand |
| SEPHS1 | selenophosphate synthetase 1 |
| SEPW1 | selenoprotein W, 1 |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SH3BP2 | SH3-domain binding protein 2 |
| SIRT7 | sirtuin 7 |
| SKAP2 | src kinase associated phosphoprotein 2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| TAF1B | TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TGM2 | transglutaminase 2 |
| TIPIN | TIMELESS interacting protein |
| TMEM127 | transmembrane protein 127 |
| TMEM161A | transmembrane protein 161A |
| TSPAN31 | tetraspanin 31 |
| TSR3 | TSR3, 20S rRNA accumulation, homolog (S. cerevisiae) |
| UBA7 | ubiquitin-like modifier activating enzyme 7 |
| VPS13D | vacuolar protein sorting 13 homolog D (S. cerevisiae) |
| XPA | xeroderma pigmentosum, complementation group A |
| ZBTB43 | zinc finger and BTB domain containing 43 |
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACP6 | acid phosphatase 6, lysophosphatidic |
| ACVRL1 | activin A receptor type II-like 1 |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| ALDOC | aldolase C, fructose-bisphosphate |
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
| APCS | amyloid P component, serum |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| AXIN1 | axin 1 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BCL2L14 | BCL2-like 14 (apoptosis facilitator) |
| BHMT | betaine--homocysteine S-methyltransferase |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C9ORF114 | chromosome 9 open reading frame 114 |
| CA9 | carbonic anhydrase IX |
| CBY1 | chibby homolog 1 (Drosophila) |
| CCDC176 | coiled-coil domain containing 176 |
| CCR4 | chemokine (C-C motif) receptor 4 |
| CDC37 | cell division cycle 37 |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLDN11 | claudin 11 |
| COMMD10 | COMM domain containing 10 |
| CRYAB | crystallin, alpha B |
| CTRB2 | chymotrypsinogen B2 |
| DENND4C | DENN/MADD domain containing 4C |
| DMTN | dematin actin binding protein |
| DPEP1 | dipeptidase 1 (renal) |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| ERCC4 | excision repair cross-complementation group 4 |
| ERMP1 | endoplasmic reticulum metallopeptidase 1 |
| FBXO2 | F-box protein 2 |
| FUZ | fuzzy planar cell polarity protein |
| G0S2 | G0/G1 switch 2 |
| GRHL2 | grainyhead-like 2 (Drosophila) |
| GRPR | gastrin-releasing peptide receptor |
| GSTA4 | glutathione S-transferase alpha 4 |
| HAND1 | heart and neural crest derivatives expressed 1 |
| HBBP1 | hemoglobin, beta pseudogene 1 |
| HDAC11 | histone deacetylase 11 |
| HIST1H2BI | histone cluster 1, H2bi |
| HMOX1 | heme oxygenase 1 |
| HOOK2 | hook microtubule-tethering protein 2 |
| HOXB1 | homeobox B1 |
| IL22 | interleukin 22 |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| KRT37 | keratin 37, type I |
| LEMD3 | LEM domain containing 3 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LINC00574 | long intergenic non-protein coding RNA 574 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MACROD1 | MACRO domain containing 1 |
| MGMT | O-6-methylguanine-DNA methyltransferase |
| MOXD1 | monooxygenase, DBH-like 1 |
| MTHFS | 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) |
| MYO19 | myosin XIX |
| NABP2 | nucleic acid binding protein 2 |
| NAPG | N-ethylmaleimide-sensitive factor attachment protein, gamma |
| OR2S2 | olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene) |
| OR6A2 | olfactory receptor, family 6, subfamily A, member 2 |
| P2RX7 | purinergic receptor P2X, ligand gated ion channel, 7 |
| PAX1 | paired box 1 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PICK1 | protein interacting with PRKCA 1 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma |
| PLA2G10 | phospholipase A2, group X |
| PLD2 | phospholipase D2 |
| POMZP3 | POM121 and ZP3 fusion |
| PRSS22 | protease, serine, 22 |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| RLBP1 | retinaldehyde binding protein 1 |
| RNF121 | ring finger protein 121 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SOX21 | SRY (sex determining region Y)-box 21 |
| ST5 | suppression of tumorigenicity 5 |
| STMN4 | stathmin-like 4 |
| TCTN1 | tectonic family member 1 |
| TGFB3 | transforming growth factor, beta 3 |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
| THRB | thyroid hormone receptor, beta |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TP53I3 | tumor protein p53 inducible protein 3 |
| UBL4A | ubiquitin-like 4A |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| WT1-AS | WT1 antisense RNA |
| ZBTB16 | zinc finger and BTB domain containing 16 |
| ZNF219 | zinc finger protein 219 |
| ZNF770 | zinc finger protein 770 |
| ZNF816 | zinc finger protein 816 |
