talampicillin-2954 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the talampicillin-2954 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADD2 adducin 2 (beta)
ALDH1L1 aldehyde dehydrogenase 1 family, member L1
ALOXE3 arachidonate lipoxygenase 3
AREG amphiregulin
ARMC9 armadillo repeat containing 9
B9D1 B9 protein domain 1
BCAS3 breast carcinoma amplified sequence 3
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNB3 calcium channel, voltage-dependent, beta 3 subunit
CAPN15 calpain 15
CASC1 cancer susceptibility candidate 1
CCND2 cyclin D2
CD160 CD160 molecule
CDC14A cell division cycle 14A
CELA2A chymotrypsin-like elastase family, member 2A
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CNGB3 cyclic nucleotide gated channel beta 3
CNOT4 CCR4-NOT transcription complex, subunit 4
COL4A2 collagen, type IV, alpha 2
CORO1B coronin, actin binding protein, 1B
CRAT carnitine O-acetyltransferase
CTIF CBP80/20-dependent translation initiation factor
CUL3 cullin 3
CXXC4 CXXC finger protein 4
CYTH1 cytohesin 1
DCAF15 DDB1 and CUL4 associated factor 15
DNAJC1 DnaJ (Hsp40) homolog, subfamily C, member 1
DSG2 desmoglein 2
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EHD1 EH-domain containing 1
EPHB6 EPH receptor B6
ESRRA estrogen-related receptor alpha
ETV7 ets variant 7
FMO5 flavin containing monooxygenase 5
FSTL3 follistatin-like 3 (secreted glycoprotein)
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLI3 GLI family zinc finger 3
GLRA1 glycine receptor, alpha 1
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GPC1 glypican 1
GPR182 G protein-coupled receptor 182
GPR35 G protein-coupled receptor 35
HYAL2 hyaluronoglucosaminidase 2
ICAM1 intercellular adhesion molecule 1
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IZUMO4 IZUMO family member 4
KCNK1 potassium channel, two pore domain subfamily K, member 1
LMNA lamin A/C
MAL mal, T-cell differentiation protein
MAOA monoamine oxidase A
MEFV Mediterranean fever
MMP25 matrix metallopeptidase 25
MR1 major histocompatibility complex, class I-related
MRAS muscle RAS oncogene homolog
MSC musculin
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
NQO1 NAD(P)H dehydrogenase, quinone 1
OCLM oculomedin
OPRL1 opiate receptor-like 1
PAPOLG poly(A) polymerase gamma
PCDH9 protocadherin 9
PCSK6 proprotein convertase subtilisin/kexin type 6
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
POU6F1 POU class 6 homeobox 1
PTCRA pre T-cell antigen receptor alpha
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHOD ras homolog family member D
RPL14 ribosomal protein L14
RPS28 ribosomal protein S28
RUFY3 RUN and FYVE domain containing 3
SELPLG selectin P ligand
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SMAD3 SMAD family member 3
SMG7 SMG7 nonsense mediated mRNA decay factor
SPTBN5 spectrin, beta, non-erythrocytic 5
SRCAP Snf2-related CREBBP activator protein
SULT4A1 sulfotransferase family 4A, member 1
SYNE2 spectrin repeat containing, nuclear envelope 2
TBCD tubulin folding cofactor D
TFR2 transferrin receptor 2
TLDC1 TBC/LysM-associated domain containing 1
TLN2 talin 2
TNNT1 troponin T type 1 (skeletal, slow)
TPMT thiopurine S-methyltransferase
TRAM2 translocation associated membrane protein 2
TRIM16 tripartite motif containing 16
TRIM29 tripartite motif containing 29
YY1 YY1 transcription factor
ZBTB7A zinc finger and BTB domain containing 7A
ZER1 zyg-11 related, cell cycle regulator
ZHX3 zinc fingers and homeoboxes 3
ZNF609 zinc finger protein 609
ZNF747 zinc finger protein 747

decreased expression

Symbol Name
ACTL6A actin-like 6A
AGBL5 ATP/GTP binding protein-like 5
AIM2 absent in melanoma 2
AP1G1 adaptor-related protein complex 1, gamma 1 subunit
ARFGAP1 ADP-ribosylation factor GTPase activating protein 1
BATF basic leucine zipper transcription factor, ATF-like
BCOR BCL6 corepressor
BOLA1 bolA family member 1
C11ORF68 chromosome 11 open reading frame 68
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCNL2 cyclin L2
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CDK3 cyclin-dependent kinase 3
CFAP44 cilia and flagella associated protein 44
CLGN calmegin
COL15A1 collagen, type XV, alpha 1
COMMD3 COMM domain containing 3
CPNE1 copine I
CSK c-src tyrosine kinase
CX3CR1 chemokine (C-X3-C motif) receptor 1
DNAAF2 dynein, axonemal, assembly factor 2
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
ERCC8 excision repair cross-complementation group 8
FADD Fas (TNFRSF6)-associated via death domain
FANCC Fanconi anemia, complementation group C
FANCF Fanconi anemia, complementation group F
FBXO5 F-box protein 5
FUBP3 far upstream element (FUSE) binding protein 3
GIMAP6 GTPase, IMAP family member 6
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GRAMD1B GRAM domain containing 1B
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
HEATR3 HEAT repeat containing 3
HELLS helicase, lymphoid-specific
HHLA3 HERV-H LTR-associating 3
HIST1H2AJ histone cluster 1, H2aj
IMPACT impact RWD domain protein
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITPKB inositol-trisphosphate 3-kinase B
KIF18A kinesin family member 18A
KIFAP3 kinesin-associated protein 3
KLHL21 kelch-like family member 21
LINC00115 long intergenic non-protein coding RNA 115
LINS lines homolog (Drosophila)
METTL22 methyltransferase like 22
MICU2 mitochondrial calcium uptake 2
MMP2 matrix metallopeptidase 2
MRPL49 mitochondrial ribosomal protein L49
MT1HL1 metallothionein 1H-like 1
NCAPH non-SMC condensin I complex, subunit H
NPIPB3 nuclear pore complex interacting protein family, member B3
PHC1 polyhomeotic homolog 1 (Drosophila)
PIAS3 protein inhibitor of activated STAT, 3
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PJA1 praja ring finger 1, E3 ubiquitin protein ligase
POLR2F polymerase (RNA) II (DNA directed) polypeptide F
PRDM13 PR domain containing 13
PTX3 pentraxin 3, long
PXMP4 peroxisomal membrane protein 4, 24kDa
RAD51AP1 RAD51 associated protein 1
RBBP5 retinoblastoma binding protein 5
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RPA4 replication protein A4, 30kDa
S100A9 S100 calcium binding protein A9
SASH3 SAM and SH3 domain containing 3
SCRIB scribbled planar cell polarity protein
SFXN1 sideroflexin 1
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SH3YL1 SH3 and SYLF domain containing 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SOHLH2 spermatogenesis and oogenesis specific basic helix-loop-helix 2
SPC25 SPC25, NDC80 kinetochore complex component
SREBF1 sterol regulatory element binding transcription factor 1
STBD1 starch binding domain 1
SURF2 surfeit 2
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TEP1 telomerase-associated protein 1
TET3 tet methylcytosine dioxygenase 3
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMEM184C transmembrane protein 184C
TMOD3 tropomodulin 3 (ubiquitous)
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TPST2 tyrosylprotein sulfotransferase 2
TRAPPC2L trafficking protein particle complex 2-like
TRIM28 tripartite motif containing 28
TSPYL2 TSPY-like 2
USP32 ubiquitin specific peptidase 32
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WRAP73 WD repeat containing, antisense to TP73
YY2 YY2 transcription factor
ZBTB48 zinc finger and BTB domain containing 48
ZNF37BP zinc finger protein 37B, pseudogene
ZSCAN16 zinc finger and SCAN domain containing 16
ZSCAN5A zinc finger and SCAN domain containing 5A