talampicillin-3515 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the talampicillin-3515 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
ANKRD7 ankyrin repeat domain 7
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ATF6B activating transcription factor 6 beta
ATM ATM serine/threonine kinase
ATP7A ATPase, Cu++ transporting, alpha polypeptide
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CALCR calcitonin receptor
CC2D1A coiled-coil and C2 domain containing 1A
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CRIP1 cysteine-rich protein 1 (intestinal)
CTBP2 C-terminal binding protein 2
CUL7 cullin 7
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
DYSF dysferlin
ELOVL5 ELOVL fatty acid elongase 5
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ERAP1 endoplasmic reticulum aminopeptidase 1
FAM131A family with sequence similarity 131, member A
FAM65A family with sequence similarity 65, member A
FAM76A family with sequence similarity 76, member A
FBXO40 F-box protein 40
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
GFI1 growth factor independent 1 transcription repressor
GLIPR1 GLI pathogenesis-related 1
GPR137 G protein-coupled receptor 137
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GYPB glycophorin B (MNS blood group)
HIST1H3F histone cluster 1, H3f
HMOX1 heme oxygenase 1
HOXA4 homeobox A4
HYAL1 hyaluronoglucosaminidase 1
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGHM immunoglobulin heavy constant mu
IVL involucrin
KCTD7 potassium channel tetramerization domain containing 7
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIAA0930 KIAA0930
KIF1C kinesin family member 1C
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
MAK male germ cell-associated kinase
MAN1A2 mannosidase, alpha, class 1A, member 2
MAPK7 mitogen-activated protein kinase 7
MCPH1 microcephalin 1
MMRN2 multimerin 2
MST1 macrophage stimulating 1
MUC1 mucin 1, cell surface associated
MX1 MX dynamin-like GTPase 1
NRL neural retina leucine zipper
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OR7A10 olfactory receptor, family 7, subfamily A, member 10
OSBP2 oxysterol binding protein 2
OSMR oncostatin M receptor
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4
PAX3 paired box 3
PGR progesterone receptor
PHF1 PHD finger protein 1
PHLDB1 pleckstrin homology-like domain, family B, member 1
PIGC phosphatidylinositol glycan anchor biosynthesis, class C
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLEK pleckstrin
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PSG4 pregnancy specific beta-1-glycoprotein 4
PTCRA pre T-cell antigen receptor alpha
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RNGTT RNA guanylyltransferase and 5'-phosphatase
RUNX1 runt-related transcription factor 1
S100A13 S100 calcium binding protein A13
SCN10A sodium channel, voltage gated, type X alpha subunit
SDS serine dehydratase
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TEP1 telomerase-associated protein 1
TLDC1 TBC/LysM-associated domain containing 1
TMEM19 transmembrane protein 19
TRIM14 tripartite motif containing 14
TYRP1 tyrosinase-related protein 1
UBOX5 U-box domain containing 5
USP36 ubiquitin specific peptidase 36
WSB1 WD repeat and SOCS box containing 1
ZBTB7A zinc finger and BTB domain containing 7A
ZIM2 zinc finger, imprinted 2
ZMAT4 zinc finger, matrin-type 4
ZNF230 zinc finger protein 230
ZNF384 zinc finger protein 384
ZNF419 zinc finger protein 419
ZNF506 zinc finger protein 506
ZNF783 zinc finger family member 783
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ABI3BP ABI family, member 3 (NESH) binding protein
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACAD10 acyl-CoA dehydrogenase family, member 10
ADGRE5 adhesion G protein-coupled receptor E5
ADGRG2 adhesion G protein-coupled receptor G2
AFF4 AF4/FMR2 family, member 4
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BFSP1 beaded filament structural protein 1, filensin
C10ORF95 chromosome 10 open reading frame 95
C14ORF79 chromosome 14 open reading frame 79
C19ORF40 chromosome 19 open reading frame 40
C5 complement component 5
C7ORF43 chromosome 7 open reading frame 43
CAPG capping protein (actin filament), gelsolin-like
CCDC68 coiled-coil domain containing 68
CEMIP cell migration inducing protein, hyaluronan binding
CEP170B centrosomal protein 170B
CNGB3 cyclic nucleotide gated channel beta 3
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRELD1 cysteine-rich with EGF-like domains 1
CRY2 cryptochrome circadian clock 2
CTSF cathepsin F
CXCR2 chemokine (C-X-C motif) receptor 2
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNA3 ephrin-A3
ERCC4 excision repair cross-complementation group 4
ERN2 endoplasmic reticulum to nucleus signaling 2
ETAA1 Ewing tumor-associated antigen 1
FAM63A family with sequence similarity 63, member A
FANCE Fanconi anemia, complementation group E
FLNC filamin C, gamma
FOXN2 forkhead box N2
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GCHFR GTP cyclohydrolase I feedback regulator
GEMIN8 gem (nuclear organelle) associated protein 8
HHLA3 HERV-H LTR-associating 3
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
INO80D INO80 complex subunit D
IRF1 interferon regulatory factor 1
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIF13A kinesin family member 13A
KIF13B kinesin family member 13B
KLHL25 kelch-like family member 25
KRT24 keratin 24, type I
LAMB2 laminin, beta 2 (laminin S)
LIME1 Lck interacting transmembrane adaptor 1
LRP5L low density lipoprotein receptor-related protein 5-like
MAGEA3 melanoma antigen family A3
MAGEA6 melanoma antigen family A6
MAP1S microtubule-associated protein 1S
MATK megakaryocyte-associated tyrosine kinase
MBTD1 mbt domain containing 1
MFAP2 microfibrillar-associated protein 2
MITF microphthalmia-associated transcription factor
MYO1F myosin IF
N4BP3 NEDD4 binding protein 3
NEIL3 nei endonuclease VIII-like 3 (E. coli)
NPM3 nucleophosmin/nucleoplasmin 3
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
P3H1 prolyl 3-hydroxylase 1
PLD2 phospholipase D2
PLXNA3 plexin A3
POM121 POM121 transmembrane nucleoporin
POR P450 (cytochrome) oxidoreductase
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PRR7 proline rich 7 (synaptic)
QPCTL glutaminyl-peptide cyclotransferase-like
RASL11B RAS-like, family 11, member B
RNF126P1 ring finger protein 126 pseudogene 1
RNF170 ring finger protein 170
ROM1 retinal outer segment membrane protein 1
RPAP1 RNA polymerase II associated protein 1
RUSC2 RUN and SH3 domain containing 2
SCRN3 secernin 3
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC41A3 solute carrier family 41, member 3
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SPRYD7 SPRY domain containing 7
STAG3 stromal antigen 3
STARD3 StAR-related lipid transfer (START) domain containing 3
STK16 serine/threonine kinase 16
STRN4 striatin, calmodulin binding protein 4
TCP10 t-complex 10
TICAM1 toll-like receptor adaptor molecule 1
TMEM57 transmembrane protein 57
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TSGA10 testis specific, 10
WDR4 WD repeat domain 4
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZC3H3 zinc finger CCCH-type containing 3
ZNF282 zinc finger protein 282
ZNF428 zinc finger protein 428
ZNF532 zinc finger protein 532
ZNF669 zinc finger protein 669
ZNF816 zinc finger protein 816