Talipes calcaneovalgus is a flexible foot deformity (as opposed to a rigid congenital vertical talus foot deformity) that can either present as a positional or structural foot deformity depending on severity and/or causality. The axis of calcaneovalgus deformity is in the tibiotalar joint, where the foot is positioned in extreme hyperextension. On inspection, the foot has an up and out appearance, with the dorsal forefoot practically touching the anterior aspect of the ankle and lower leg. (Human Phenotype Ontology, HP_0001884)
7 genes associated with the talipes calcaneovalgus phenotype by mapping known disease genes to disease phenotypes from the HPO Gene-Disease Associations dataset.