tamoxifen-1366 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the tamoxifen-1366 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ARFRP1 ADP-ribosylation factor related protein 1
ARRB2 arrestin, beta 2
ASPH aspartate beta-hydroxylase
ATG13 autophagy related 13
BCL2A1 BCL2-related protein A1
BCL7C B-cell CLL/lymphoma 7C
BPI bactericidal/permeability-increasing protein
BRIX1 BRX1, biogenesis of ribosomes
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
C12ORF29 chromosome 12 open reading frame 29
C5AR1 complement component 5a receptor 1
CCL5 chemokine (C-C motif) ligand 5
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CFDP1 craniofacial development protein 1
CNOT3 CCR4-NOT transcription complex, subunit 3
CXCR4 chemokine (C-X-C motif) receptor 4
DERL2 derlin 2
DGCR8 DGCR8 microprocessor complex subunit
DSCR3 Down syndrome critical region 3
E2F1 E2F transcription factor 1
EGR3 early growth response 3
EID1 EP300 interacting inhibitor of differentiation 1
EIF5B eukaryotic translation initiation factor 5B
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FTH1P5 ferritin, heavy polypeptide 1 pseudogene 5
GNAS GNAS complex locus
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIGD2A HIG1 hypoxia inducible domain family, member 2A
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1
HOMER3 homer scaffolding protein 3
HTT huntingtin
HUS1 HUS1 checkpoint homolog (S. pombe)
IGFBP7 insulin-like growth factor binding protein 7
IL1R2 interleukin 1 receptor, type II
ISOC1 isochorismatase domain containing 1
JAG1 jagged 1
KCTD5 potassium channel tetramerization domain containing 5
KDSR 3-ketodihydrosphingosine reductase
KHSRP KH-type splicing regulatory protein
KLHL20 kelch-like family member 20
KLHL7 kelch-like family member 7
KTN1 kinectin 1 (kinesin receptor)
LPPR2 lipid phosphate phosphatase-related protein type 2
LRRC41 leucine rich repeat containing 41
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAGOHB mago-nashi homolog B (Drosophila)
MAZ MYC-associated zinc finger protein (purine-binding transcription factor)
MSH3 mutS homolog 3
MTMR6 myotubularin related protein 6
MZF1 myeloid zinc finger 1
NAT6 N-acetyltransferase 6 (GCN5-related)
NET1 neuroepithelial cell transforming 1
NFE2L2 nuclear factor, erythroid 2-like 2
PAQR3 progestin and adipoQ receptor family member III
PRMT3 protein arginine methyltransferase 3
PSPH phosphoserine phosphatase
RAB5C RAB5C, member RAS oncogene family
RAD23A RAD23 homolog A (S. cerevisiae)
RARS arginyl-tRNA synthetase
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RCN2 reticulocalbin 2, EF-hand calcium binding domain
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RGCC regulator of cell cycle
RGS1 regulator of G-protein signaling 1
RPS2 ribosomal protein S2
SAP30 Sin3A-associated protein, 30kDa
SCAMP1 secretory carrier membrane protein 1
SCML1 sex comb on midleg-like 1 (Drosophila)
SEC23B Sec23 homolog B (S. cerevisiae)
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SGSM2 small G protein signaling modulator 2
SLC4A7 solute carrier family 4, sodium bicarbonate cotransporter, member 7
SMIM7 small integral membrane protein 7
SOCS5 suppressor of cytokine signaling 5
SRCAP Snf2-related CREBBP activator protein
SRSF10 serine/arginine-rich splicing factor 10
STK19 serine/threonine kinase 19
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
THTPA thiamine triphosphatase
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TMED7 transmembrane emp24 protein transport domain containing 7
TMEM5 transmembrane protein 5
TNFAIP6 tumor necrosis factor, alpha-induced protein 6
TPT1 tumor protein, translationally-controlled 1
TSEN2 TSEN2 tRNA splicing endonuclease subunit
UNC93B1 unc-93 homolog B1 (C. elegans)
URI1 URI1, prefoldin-like chaperone
VAC14 Vac14 homolog (S. cerevisiae)
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
WASF1 WAS protein family, member 1
WDR46 WD repeat domain 46
WIZ widely interspaced zinc finger motifs
XPC xeroderma pigmentosum, complementation group C
ZEB2 zinc finger E-box binding homeobox 2
ZNF468 zinc finger protein 468
ZNF580 zinc finger protein 580

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABHD11 abhydrolase domain containing 11
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ACVR2A activin A receptor, type IIA
ACVR2B activin A receptor, type IIB
ASB13 ankyrin repeat and SOCS box containing 13
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATG9A autophagy related 9A
B3GNT1
C6ORF47 chromosome 6 open reading frame 47
CA7 carbonic anhydrase VII
CALCOCO1 calcium binding and coiled-coil domain 1
CCNT1 cyclin T1
CEND1 cell cycle exit and neuronal differentiation 1
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CTAGE9 CTAGE family, member 9
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DSN1 DSN1, MIS12 kinetochore complex component
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ERCC6 excision repair cross-complementation group 6
FAM114A1 family with sequence similarity 114, member A1
FAM160B2 family with sequence similarity 160, member B2
FAM53B family with sequence similarity 53, member B
FGF4 fibroblast growth factor 4
FOXK2 forkhead box K2
GDF9 growth differentiation factor 9
GLB1L2 galactosidase, beta 1-like 2
GOLPH3L golgi phosphoprotein 3-like
HINFP histone H4 transcription factor
HIST1H1C histone cluster 1, H1c
HIST3H2A histone cluster 3, H2a
HK1 hexokinase 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IGFLR1 IGF-like family receptor 1
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
INF2 inverted formin, FH2 and WH2 domain containing
INPPL1 inositol polyphosphate phosphatase-like 1
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LMTK1 lemur tail kinase 1
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
MAGEF1 melanoma antigen family F1
MEPCE methylphosphate capping enzyme
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTG1 mitochondrial ribosome-associated GTPase 1
NECAB3 N-terminal EF-hand calcium binding protein 3
NHEJ1 nonhomologous end-joining factor 1
NOD1 nucleotide-binding oligomerization domain containing 1
NSD1 nuclear receptor binding SET domain protein 1
NXPH3 neurexophilin 3
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
PCDHGB5 protocadherin gamma subfamily B, 5
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PIGR polymeric immunoglobulin receptor
PRR14L proline rich 14-like
RABL6 RAB, member RAS oncogene family-like 6
RETSAT retinol saturase (all-trans-retinol 13,14-reductase)
RFPL3 ret finger protein-like 3
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RGP1 RGP1 retrograde golgi transport homolog (S. cerevisiae)
RNF122 ring finger protein 122
RPAP1 RNA polymerase II associated protein 1
RPL23AP32 ribosomal protein L23a pseudogene 32
SCAMP5 secretory carrier membrane protein 5
SIRT6 sirtuin 6
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae)
SLC22A14 solute carrier family 22, member 14
SLN sarcolipin
SNRNP35 small nuclear ribonucleoprotein 35kDa (U11/U12)
SNTA1 syntrophin, alpha 1
SNX6 sorting nexin 6
SPAG7 sperm associated antigen 7
SPX spexin hormone
SRRD SRR1 domain containing
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
STAC SH3 and cysteine rich domain
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TCTN2 tectonic family member 2
TEX40 testis expressed 40
TMPRSS6 transmembrane protease, serine 6
TOR4A torsin family 4, member A
TRIM22 tripartite motif containing 22
TRIM26 tripartite motif containing 26
TRIM66 tripartite motif containing 66
TTPAL tocopherol (alpha) transfer protein-like
TXLNA taxilin alpha
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UNC13B unc-13 homolog B (C. elegans)
URGCP upregulator of cell proliferation
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
XKR8 XK, Kell blood group complex subunit-related family, member 8
ZC3H3 zinc finger CCCH-type containing 3
ZNF529 zinc finger protein 529
ZSCAN26 zinc finger and SCAN domain containing 26
ZSCAN9 zinc finger and SCAN domain containing 9