tamoxifen-143 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the tamoxifen-143 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACRV1 acrosomal vesicle protein 1
AHR aryl hydrocarbon receptor
ALPK1 alpha-kinase 1
APAF1 apoptotic peptidase activating factor 1
ARMC7 armadillo repeat containing 7
AUNIP aurora kinase A and ninein interacting protein
BMP7 bone morphogenetic protein 7
C1ORF174 chromosome 1 open reading frame 174
C1ORF61 chromosome 1 open reading frame 61
CALHM2 calcium homeostasis modulator 2
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD22 CD22 molecule
CDC40 cell division cycle 40
CHERP calcium homeostasis endoplasmic reticulum protein
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CIC capicua transcriptional repressor
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CREM cAMP responsive element modulator
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DCAF6 DDB1 and CUL4 associated factor 6
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DPY19L1 dpy-19-like 1 (C. elegans)
F5 coagulation factor V (proaccelerin, labile factor)
FAM49B family with sequence similarity 49, member B
FANCF Fanconi anemia, complementation group F
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FOLR1 folate receptor 1 (adult)
FPR1 formyl peptide receptor 1
GOLGA4 golgin A4
GRIK5 glutamate receptor, ionotropic, kainate 5
GSK3A glycogen synthase kinase 3 alpha
GYPB glycophorin B (MNS blood group)
HFE hemochromatosis
HIGD1A HIG1 hypoxia inducible domain family, member 1A
HIST1H2BG histone cluster 1, H2bg
HMMR hyaluronan-mediated motility receptor (RHAMM)
HSPA9 heat shock 70kDa protein 9 (mortalin)
IFNA10 interferon, alpha 10
ISG20L2 interferon stimulated exonuclease gene 20kDa-like 2
KLF15 Kruppel-like factor 15
KLHL24 kelch-like family member 24
LUZP1 leucine zipper protein 1
MED8 mediator complex subunit 8
MOB1A MOB kinase activator 1A
MRPS30 mitochondrial ribosomal protein S30
MTO1 mitochondrial tRNA translation optimization 1
MYCBP MYC binding protein
NCAN neurocan
NENF neudesin neurotrophic factor
NEUROD2 neuronal differentiation 2
NKX3-1 NK3 homeobox 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OR2H2 olfactory receptor, family 2, subfamily H, member 2
PC pyruvate carboxylase
PCNX pecanex homolog (Drosophila)
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEK pleckstrin
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
POT1 protection of telomeres 1
PPP1R8 protein phosphatase 1, regulatory subunit 8
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
RAB8B RAB8B, member RAS oncogene family
RAI14 retinoic acid induced 14
RGS12 regulator of G-protein signaling 12
RLBP1 retinaldehyde binding protein 1
SAP18 Sin3A-associated protein, 18kDa
SARAF store-operated calcium entry-associated regulatory factor
SC5D sterol-C5-desaturase
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SPN sialophorin
STXBP6 syntaxin binding protein 6 (amisyn)
STYXL1 serine/threonine/tyrosine interacting-like 1
SURF2 surfeit 2
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
SYNE2 spectrin repeat containing, nuclear envelope 2
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TAOK1 TAO kinase 1
TAOK2 TAO kinase 2
TBXA2R thromboxane A2 receptor
TCEAL1 transcription elongation factor A (SII)-like 1
TEAD4 TEA domain family member 4
TIMM10B translocase of inner mitochondrial membrane 10 homolog B (yeast)
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TOR1AIP1 torsin A interacting protein 1
TP53BP1 tumor protein p53 binding protein 1
TSC22D3 TSC22 domain family, member 3
TUBA3C tubulin, alpha 3c
UROD uroporphyrinogen decarboxylase
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae)
VRK3 vaccinia related kinase 3
VWA8 von Willebrand factor A domain containing 8
ZNF286A zinc finger protein 286A
ZNF358 zinc finger protein 358
ZNF408 zinc finger protein 408
ZNF576 zinc finger protein 576

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ADCK3 aarF domain containing kinase 3
ADM2 adrenomedullin 2
AEN apoptosis enhancing nuclease
AIPL1 aryl hydrocarbon receptor interacting protein-like 1
AMT aminomethyltransferase
ANKRD46 ankyrin repeat domain 46
AP3M2 adaptor-related protein complex 3, mu 2 subunit
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2
ARRB2 arrestin, beta 2
ASB13 ankyrin repeat and SOCS box containing 13
ASB6 ankyrin repeat and SOCS box containing 6
ASIC4 acid sensing (proton gated) ion channel family member 4
ATXN2 ataxin 2
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BARX2 BARX homeobox 2
BCL2L14 BCL2-like 14 (apoptosis facilitator)
CA14 carbonic anhydrase XIV
CADPS2 Ca++-dependent secretion activator 2
CAPG capping protein (actin filament), gelsolin-like
CAV3 caveolin 3
CCDC7 coiled-coil domain containing 7
CCNL2 cyclin L2
CCS copper chaperone for superoxide dismutase
CD82 CD82 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CFAP74 cilia and flagella associated protein 74
CHAF1B chromatin assembly factor 1, subunit B (p60)
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CLCA1 chloride channel accessory 1
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COG7 component of oligomeric golgi complex 7
CPTP ceramide-1-phosphate transfer protein
CRABP1 cellular retinoic acid binding protein 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DCP1A decapping mRNA 1A
DTL denticleless E3 ubiquitin protein ligase homolog (Drosophila)
EGR3 early growth response 3
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative)
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOSC9 exosome component 9
FAM86C1 family with sequence similarity 86, member C1
FLNC filamin C, gamma
FMO6P flavin containing monooxygenase 6 pseudogene
FMOD fibromodulin
GRM4 glutamate receptor, metabotropic 4
GRWD1 glutamate-rich WD repeat containing 1
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IL2RB interleukin 2 receptor, beta
INTS12 integrator complex subunit 12
JOSD1 Josephin domain containing 1
KIF20B kinesin family member 20B
MAL mal, T-cell differentiation protein
MALL mal, T-cell differentiation protein-like
MITF microphthalmia-associated transcription factor
MNT MAX network transcriptional repressor
MRPL41 mitochondrial ribosomal protein L41
MRPL52 mitochondrial ribosomal protein L52
MTG1 mitochondrial ribosome-associated GTPase 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MVP major vault protein
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NDC80 NDC80 kinetochore complex component
NIPAL2 NIPA-like domain containing 2
NOD1 nucleotide-binding oligomerization domain containing 1
NOL6 nucleolar protein 6 (RNA-associated)
NXPH4 neurexophilin 4
PABPC3 poly(A) binding protein, cytoplasmic 3
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PADI1 peptidyl arginine deiminase, type I
PFAS phosphoribosylformylglycinamidine synthase
PLCD1 phospholipase C, delta 1
PLXNA3 plexin A3
PRAF2 PRA1 domain family, member 2
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PZP pregnancy-zone protein
RAB3D RAB3D, member RAS oncogene family
RAP1A RAP1A, member of RAS oncogene family
RHOF ras homolog family member F (in filopodia)
RIPK4 receptor-interacting serine-threonine kinase 4
SSBP3 single stranded DNA binding protein 3
STK16 serine/threonine kinase 16
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SUN2 Sad1 and UNC84 domain containing 2
T T, brachyury homolog (mouse)
TCEA2 transcription elongation factor A (SII), 2
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast)
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TRPM2 transient receptor potential cation channel, subfamily M, member 2
TRPV2 transient receptor potential cation channel, subfamily V, member 2
TSEN2 TSEN2 tRNA splicing endonuclease subunit
VEGFB vascular endothelial growth factor B
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
ZFHX2 zinc finger homeobox 2
ZNF552 zinc finger protein 552