tamoxifen-2212 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the tamoxifen-2212 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AHNAK AHNAK nucleoprotein
ATF3 activating transcription factor 3
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2
BHLHE40 basic helix-loop-helix family, member e40
BIRC3 baculoviral IAP repeat containing 3
CCDC106 coiled-coil domain containing 106
CCNG2 cyclin G2
CDK19 cyclin-dependent kinase 19
CDRT1 CMT1A duplicated region transcript 1
CGA glycoprotein hormones, alpha polypeptide
CLEC4A C-type lectin domain family 4, member A
CRTC1 CREB regulated transcription coactivator 1
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DGCR2 DiGeorge syndrome critical region gene 2
DGKQ diacylglycerol kinase, theta 110kDa
DLX2 distal-less homeobox 2
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
DOK4 docking protein 4
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
EFNA1 ephrin-A1
EFNB3 ephrin-B3
EGR1 early growth response 1
FAM46C family with sequence similarity 46, member C
FLJ11292
FOS FBJ murine osteosarcoma viral oncogene homolog
GADD45A growth arrest and DNA-damage-inducible, alpha
GEM GTP binding protein overexpressed in skeletal muscle
HBEGF heparin-binding EGF-like growth factor
HIST1H1T histone cluster 1, H1t
HIST1H2AE histone cluster 1, H2ae
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BO histone cluster 1, H2bo
HIST1H3B histone cluster 1, H3b
HIST1H4H histone cluster 1, H4h
HOXB2 homeobox B2
HSPB6 heat shock protein, alpha-crystallin-related, B6
ICAM1 intercellular adhesion molecule 1
IER2 immediate early response 2
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL23A interleukin 23, alpha subunit p19
IL32 interleukin 32
INHBE inhibin, beta E
IRF1 interferon regulatory factor 1
ISG20 interferon stimulated exonuclease gene 20kDa
JUN jun proto-oncogene
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KLF10 Kruppel-like factor 10
KLF2 Kruppel-like factor 2
KLF6 Kruppel-like factor 6
KLHL24 kelch-like family member 24
LHFPL2 lipoma HMGIC fusion partner-like 2
LTB lymphotoxin beta (TNF superfamily, member 3)
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MT1F metallothionein 1F
MT1H metallothionein 1H
MT1X metallothionein 1X
MT2A metallothionein 2A
NIPAL3 NIPA-like domain containing 3
NR4A1 nuclear receptor subfamily 4, group A, member 1
NR4A3 nuclear receptor subfamily 4, group A, member 3
NUDC nudC nuclear distribution protein
NUPR1 nuclear protein, transcriptional regulator, 1
OGDHL oxoglutarate dehydrogenase-like
PCDHA5 protocadherin alpha 5
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLXNB3 plexin B3
POU3F4 POU class 3 homeobox 4
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PSD3 pleckstrin and Sec7 domain containing 3
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RABGAP1L RAB GTPase activating protein 1-like
RCAN1 regulator of calcineurin 1
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RND1 Rho family GTPase 1
RPLP2 ribosomal protein, large, P2
RREB1 ras responsive element binding protein 1
RUNX1 runt-related transcription factor 1
S100A8 S100 calcium binding protein A8
SH3BP2 SH3-domain binding protein 2
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SPRY4 sprouty homolog 4 (Drosophila)
TBC1D2 TBC1 domain family, member 2
TCF12 transcription factor 12
TG thyroglobulin
TGFB2 transforming growth factor, beta 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
ZNF165 zinc finger protein 165
ZNF222 zinc finger protein 222
ZNF419 zinc finger protein 419

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ALG12 ALG12, alpha-1,6-mannosyltransferase
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
C16ORF59 chromosome 16 open reading frame 59
C5AR2 complement component 5a receptor 2
C9ORF9 chromosome 9 open reading frame 9
CA2 carbonic anhydrase II
CAMK1 calcium/calmodulin-dependent protein kinase I
CCDC85C coiled-coil domain containing 85C
CD302 CD302 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CDKN2D cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
CISH cytokine inducible SH2-containing protein
COCH cochlin
CRY2 cryptochrome circadian clock 2
CXCL12 chemokine (C-X-C motif) ligand 12
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DGAT1 diacylglycerol O-acyltransferase 1
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DUSP13 dual specificity phosphatase 13
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
EFNA3 ephrin-A3
ELSPBP1 epididymal sperm binding protein 1
ERCC3 excision repair cross-complementation group 3
ETAA1 Ewing tumor-associated antigen 1
EXO5 exonuclease 5
FAM57A family with sequence similarity 57, member A
FGD1 FYVE, RhoGEF and PH domain containing 1
FOXC1 forkhead box C1
GATA4 GATA binding protein 4
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GSTM5 glutathione S-transferase mu 5
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HIST1H3E histone cluster 1, H3e
HOXC8 homeobox C8
ICK intestinal cell (MAK-like) kinase
IGFBP4 insulin-like growth factor binding protein 4
IL17RA interleukin 17 receptor A
IL4R interleukin 4 receptor
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KLK5 kallikrein-related peptidase 5
KRT15 keratin 15, type I
LIME1 Lck interacting transmembrane adaptor 1
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRP2 low density lipoprotein receptor-related protein 2
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MBTD1 mbt domain containing 1
MFSD11 major facilitator superfamily domain containing 11
MOCS3 molybdenum cofactor synthesis 3
MSMB microseminoprotein, beta-
NECAB3 N-terminal EF-hand calcium binding protein 3
NPFFR1 neuropeptide FF receptor 1
NPY1R neuropeptide Y receptor Y1
NPY5R neuropeptide Y receptor Y5
OPN3 opsin 3
PADI1 peptidyl arginine deiminase, type I
PDZK1 PDZ domain containing 1
PGP phosphoglycolate phosphatase
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
POMT2 protein-O-mannosyltransferase 2
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PRSS23 protease, serine, 23
RAB30 RAB30, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RBL1 retinoblastoma-like 1
RCAN3 RCAN family member 3
RPL23AP32 ribosomal protein L23a pseudogene 32
RPUSD2 RNA pseudouridylate synthase domain containing 2
SIX1 SIX homeobox 1
SKI SKI proto-oncogene
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLIT2 slit homolog 2 (Drosophila)
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SOX3 SRY (sex determining region Y)-box 3
SPINK4 serine peptidase inhibitor, Kazal type 4
SPRYD7 SPRY domain containing 7
ST5 suppression of tumorigenicity 5
STARD3 StAR-related lipid transfer (START) domain containing 3
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TMPRSS3 transmembrane protease, serine 3
TNS2 tensin 2
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TRPV6 transient receptor potential cation channel, subfamily V, member 6
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
USP18 ubiquitin specific peptidase 18
WDR91 WD repeat domain 91
XDH xanthine dehydrogenase
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
XYLT2 xylosyltransferase II
ZMAT5 zinc finger, matrin-type 5
ZNF205 zinc finger protein 205
ZNF280D zinc finger protein 280D
ZNF480 zinc finger protein 480
ZNF721 zinc finger protein 721