tamoxifen-380 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

193 genes differentially expressed following the tamoxifen-380 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AQP1 aquaporin 1 (Colton blood group)
ARG2 arginase 2
ARHGAP33 Rho GTPase activating protein 33
ARSF arylsulfatase F
ATF7IP2 activating transcription factor 7 interacting protein 2
ATG4B autophagy related 4B, cysteine peptidase
AVIL advillin
C2CD2L C2CD2-like
C6ORF106 chromosome 6 open reading frame 106
CARHSP1 calcium regulated heat stable protein 1, 24kDa
CBX6 chromobox homolog 6
CIITA class II, major histocompatibility complex, transactivator
CLN5 ceroid-lipofuscinosis, neuronal 5
CNGB3 cyclic nucleotide gated channel beta 3
CORT cortistatin
CRYGD crystallin, gamma D
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CXCR3 chemokine (C-X-C motif) receptor 3
CYLD cylindromatosis (turban tumor syndrome)
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal
DHPS deoxyhypusine synthase
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DUS2 dihydrouridine synthase 2
E2F1 E2F transcription factor 1
EPOR erythropoietin receptor
FASTK Fas-activated serine/threonine kinase
FKBP8 FK506 binding protein 8, 38kDa
GANAB glucosidase, alpha; neutral AB
GDF3 growth differentiation factor 3
GIMAP5 GTPase, IMAP family member 5
GLG1 golgi glycoprotein 1
GSPT2 G1 to S phase transition 2
HDAC5 histone deacetylase 5
HTT huntingtin
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
INO80B INO80 complex subunit B
INSR insulin receptor
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
LGALS13 lectin, galactoside-binding, soluble, 13
LMO3 LIM domain only 3 (rhombotin-like 2)
MAGOHB mago-nashi homolog B (Drosophila)
MAML3 mastermind-like 3 (Drosophila)
MAP2K2 mitogen-activated protein kinase kinase 2
MOAP1 modulator of apoptosis 1
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MPPED1 metallophosphoesterase domain containing 1
MST1 macrophage stimulating 1
MUC1 mucin 1, cell surface associated
MYO9B myosin IXB
MZF1 myeloid zinc finger 1
NACAP1 nascent-polypeptide-associated complex alpha polypeptide pseudogene 1
NDRG3 NDRG family member 3
NPAT nuclear protein, ataxia-telangiectasia locus
NXPH3 neurexophilin 3
OLIG2 oligodendrocyte lineage transcription factor 2
ORC4 origin recognition complex, subunit 4
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
PALM paralemmin
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PITPNA phosphatidylinositol transfer protein, alpha
POLG polymerase (DNA directed), gamma
PPME1 protein phosphatase methylesterase 1
PPP4C protein phosphatase 4, catalytic subunit
PRLR prolactin receptor
PSG9 pregnancy specific beta-1-glycoprotein 9
PTPRT protein tyrosine phosphatase, receptor type, T
RASL10A RAS-like, family 10, member A
RCVRN recoverin
RGS2 regulator of G-protein signaling 2
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
SATB1 SATB homeobox 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SGK2 serum/glucocorticoid regulated kinase 2
SH3BP2 SH3-domain binding protein 2
SKAP2 src kinase associated phosphoprotein 2
SLC35E3 solute carrier family 35, member E3
SLC4A2 solute carrier family 4 (anion exchanger), member 2
STAB2 stabilin 2
SZRD1 SUZ RNA binding domain containing 1
TACR1 tachykinin receptor 1
TBX2 T-box 2
TEX13B testis expressed 13B
TIPIN TIMELESS interacting protein
TMEM127 transmembrane protein 127
TMEM209 transmembrane protein 209
TMEM70 transmembrane protein 70
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNK2 tyrosine kinase, non-receptor, 2
TSR3 TSR3, 20S rRNA accumulation, homolog (S. cerevisiae)
TUBA4B tubulin, alpha 4b
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UBA7 ubiquitin-like modifier activating enzyme 7
USF2 upstream transcription factor 2, c-fos interacting
ZBTB43 zinc finger and BTB domain containing 43
ZNF821 zinc finger protein 821

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACP6 acid phosphatase 6, lysophosphatidic
ACVRL1 activin A receptor type II-like 1
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AOAH acyloxyacyl hydrolase (neutrophil)
APOD apolipoprotein D
ARHGAP10 Rho GTPase activating protein 10
ASAP1-IT1 ASAP1 intronic transcript 1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BAHD1 bromo adjacent homology domain containing 1
BCL2L14 BCL2-like 14 (apoptosis facilitator)
BHMT betaine--homocysteine S-methyltransferase
BIN2 bridging integrator 2
C1ORF109 chromosome 1 open reading frame 109
CHMP1A charged multivesicular body protein 1A
CLCN6 chloride channel, voltage-sensitive 6
CLDN11 claudin 11
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
COX16 COX16 cytochrome c oxidase assembly homolog (S. cerevisiae)
CRYAB crystallin, alpha B
CTAGE9 CTAGE family, member 9
DENND4C DENN/MADD domain containing 4C
DPYD dihydropyrimidine dehydrogenase
DUSP13 dual specificity phosphatase 13
ERCC4 excision repair cross-complementation group 4
ERMP1 endoplasmic reticulum metallopeptidase 1
FCHO1 FCH domain only 1
FGF4 fibroblast growth factor 4
FSCN3 fascin actin-bundling protein 3, testicular
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GFI1 growth factor independent 1 transcription repressor
GML glycosylphosphatidylinositol anchored molecule like
GORASP1 golgi reassembly stacking protein 1, 65kDa
GPA33 glycoprotein A33 (transmembrane)
GPR15 G protein-coupled receptor 15
GPR35 G protein-coupled receptor 35
GRHL2 grainyhead-like 2 (Drosophila)
GRM4 glutamate receptor, metabotropic 4
GSTA4 glutathione S-transferase alpha 4
HAND1 heart and neural crest derivatives expressed 1
HBBP1 hemoglobin, beta pseudogene 1
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HS3ST2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
IREB2 iron-responsive element binding protein 2
IRF2 interferon regulatory factor 2
JAM2 junctional adhesion molecule 2
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KRT86 keratin 86, type II
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LEFTY2 left-right determination factor 2
LEMD3 LEM domain containing 3
MAPK3 mitogen-activated protein kinase 3
MGMT O-6-methylguanine-DNA methyltransferase
MNAT1 MNAT CDK-activating kinase assembly factor 1
NEO1 neogenin 1
NPAP1 nuclear pore associated protein 1
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PDE8B phosphodiesterase 8B
PELP1 proline, glutamate and leucine rich protein 1
PGC progastricsin (pepsinogen C)
PHKG2 phosphorylase kinase, gamma 2 (testis)
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLD2 phospholipase D2
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
POTEKP POTE ankyrin domain family, member K, pseudogene
PRDM5 PR domain containing 5
PRKRIP1 PRKR interacting protein 1 (IL11 inducible)
PRODH2 proline dehydrogenase (oxidase) 2
PRPSAP2 phosphoribosyl pyrophosphate synthetase-associated protein 2
PWP2 PWP2 periodic tryptophan protein homolog (yeast)
RABL6 RAB, member RAS oncogene family-like 6
RAD51AP1 RAD51 associated protein 1
RAMP3 receptor (G protein-coupled) activity modifying protein 3
RNASE3 ribonuclease, RNase A family, 3
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
SIK1 salt-inducible kinase 1
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SOX21 SRY (sex determining region Y)-box 21
STXBP1 syntaxin binding protein 1
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TAS2R1 taste receptor, type 2, member 1
TGFB3 transforming growth factor, beta 3
TPST2 tyrosylprotein sulfotransferase 2
TRIM8 tripartite motif containing 8
UBA5 ubiquitin-like modifier activating enzyme 5
UNC13B unc-13 homolog B (C. elegans)
URGCP upregulator of cell proliferation
USP11 ubiquitin specific peptidase 11
VIPR1 vasoactive intestinal peptide receptor 1
ZBTB16 zinc finger and BTB domain containing 16
ZBTB22 zinc finger and BTB domain containing 22
ZC4H2 zinc finger, C4H2 domain containing
ZNF219 zinc finger protein 219
ZNF770 zinc finger protein 770