| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the tanespimycin-1005 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| ADCY7 | adenylate cyclase 7 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| APOC4 | apolipoprotein C-IV |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BAG2 | BCL2-associated athanogene 2 |
| BLVRA | biliverdin reductase A |
| BMP4 | bone morphogenetic protein 4 |
| BST2 | bone marrow stromal cell antigen 2 |
| BTN2A2 | butyrophilin, subfamily 2, member A2 |
| CACYBP | calcyclin binding protein |
| CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
| CCNG2 | cyclin G2 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CRELD2 | cysteine-rich with EGF-like domains 2 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| DBF4B | DBF4 zinc finger B |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| ENGASE | endo-beta-N-acetylglucosaminidase |
| ERP44 | endoplasmic reticulum protein 44 |
| EXOC7 | exocyst complex component 7 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FHL1 | four and a half LIM domains 1 |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FLJ42627 | uncharacterized LOC645644 |
| FNDC3B | fibronectin type III domain containing 3B |
| GLRX | glutaredoxin (thioltransferase) |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HFE | hemochromatosis |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HSD17B7 | hydroxysteroid (17-beta) dehydrogenase 7 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA1L | heat shock 70kDa protein 1-like |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| HYOU1 | hypoxia up-regulated 1 |
| JAG1 | jagged 1 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KLHL25 | kelch-like family member 25 |
| LPIN1 | lipin 1 |
| LZTFL1 | leucine zipper transcription factor-like 1 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor |
| MAP1A | microtubule-associated protein 1A |
| MAP1B | microtubule-associated protein 1B |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MIR22HG | MIR22 host gene |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MORC4 | MORC family CW-type zinc finger 4 |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NDRG1 | N-myc downstream regulated 1 |
| NEBL | nebulette |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PASK | PAS domain containing serine/threonine kinase |
| PDIA4 | protein disulfide isomerase family A, member 4 |
| PLA2G3 | phospholipase A2, group III |
| PPID | peptidylprolyl isomerase D |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RGS2 | regulator of G-protein signaling 2 |
| RNASE4 | ribonuclease, RNase A family, 4 |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SEC24D | SEC24 family member D |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SPRR1A | small proline-rich protein 1A |
| SSBP1 | single-stranded DNA binding protein 1, mitochondrial |
| TES | testin LIM domain protein |
| THBD | thrombomodulin |
| TMEM161A | transmembrane protein 161A |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TOM1 | target of myb1 (chicken) |
| TRIM2 | tripartite motif containing 2 |
| TRIM5 | tripartite motif containing 5 |
| TSPYL2 | TSPY-like 2 |
| TUBA3C | tubulin, alpha 3c |
| ULBP2 | UL16 binding protein 2 |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 |
| ZNF165 | zinc finger protein 165 |
| ZNF222 | zinc finger protein 222 |
| ZNF227 | zinc finger protein 227 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| ACVR2B | activin A receptor, type IIB |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| ATAD3A | ATPase family, AAA domain containing 3A |
| AXIN1 | axin 1 |
| BAMBI | BMP and activin membrane-bound inhibitor |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| C1ORF35 | chromosome 1 open reading frame 35 |
| C9ORF3 | chromosome 9 open reading frame 3 |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHST10 | carbohydrate sulfotransferase 10 |
| CISH | cytokine inducible SH2-containing protein |
| CLSPN | claspin |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DNMBP | dynamin binding protein |
| EFNA1 | ephrin-A1 |
| EGR3 | early growth response 3 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| EPHA4 | EPH receptor A4 |
| FAM65A | family with sequence similarity 65, member A |
| FJX1 | four jointed box 1 (Drosophila) |
| FOXC1 | forkhead box C1 |
| GALK1 | galactokinase 1 |
| GPR19 | G protein-coupled receptor 19 |
| GTF2I | general transcription factor IIi |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HDAC4 | histone deacetylase 4 |
| HOXC11 | homeobox C11 |
| HSPBAP1 | HSPB (heat shock 27kDa) associated protein 1 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| JADE3 | jade family PHD finger 3 |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KIAA1551 | KIAA1551 |
| KLF10 | Kruppel-like factor 10 |
| KLF11 | Kruppel-like factor 11 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LOC642236 | FSHD region gene 1 pseudogene |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LRRC49 | leucine rich repeat containing 49 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MTCL1 | microtubule crosslinking factor 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NUPL2 | nucleoporin like 2 |
| NXT1 | nuclear transport factor 2-like export factor 1 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PLK2 | polo-like kinase 2 |
| PMS1 | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) |
| PRKCD | protein kinase C, delta |
| PUS1 | pseudouridylate synthase 1 |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
| RCL1 | RNA terminal phosphate cyclase-like 1 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RGS16 | regulator of G-protein signaling 16 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SMAD7 | SMAD family member 7 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SYTL2 | synaptotagmin-like 2 |
| TBCC | tubulin folding cofactor C |
| TCTA | T-cell leukemia translocation altered |
| TERF2 | telomeric repeat binding factor 2 |
| TFRC | transferrin receptor |
| TIPIN | TIMELESS interacting protein |
| TMSB15B | thymosin beta 15B |
| TPTE | transmembrane phosphatase with tensin homology |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| UNC119 | unc-119 homolog (C. elegans) |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZBTB10 | zinc finger and BTB domain containing 10 |
| ZCCHC6 | zinc finger, CCHC domain containing 6 |
| ZNF557 | zinc finger protein 557 |
| ZXDC | ZXD family zinc finger C |
