| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the tanespimycin-1044 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ARMC8 | armadillo repeat containing 8 |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| AZI2 | 5-azacytidine induced 2 |
| BAG2 | BCL2-associated athanogene 2 |
| BAG3 | BCL2-associated athanogene 3 |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
| CACYBP | calcyclin binding protein |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase |
| CCNG2 | cyclin G2 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CRELD2 | cysteine-rich with EGF-like domains 2 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| ERO1L | ERO1-like (S. cerevisiae) |
| FAM49B | family with sequence similarity 49, member B |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FKBP11 | FK506 binding protein 11, 19 kDa |
| FNDC3A | fibronectin type III domain containing 3A |
| FNDC3B | fibronectin type III domain containing 3B |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GLRX | glutaredoxin (thioltransferase) |
| GPX3 | glutathione peroxidase 3 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| HSD17B7 | hydroxysteroid (17-beta) dehydrogenase 7 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA1L | heat shock 70kDa protein 1-like |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPE1 | heat shock 10kDa protein 1 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa |
| HYOU1 | hypoxia up-regulated 1 |
| IMPACT | impact RWD domain protein |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KDM4A | lysine (K)-specific demethylase 4A |
| LDLR | low density lipoprotein receptor |
| MANF | mesencephalic astrocyte-derived neurotrophic factor |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MRPL18 | mitochondrial ribosomal protein L18 |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| OSBPL1A | oxysterol binding protein-like 1A |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PDGFRL | platelet-derived growth factor receptor-like |
| PDIA4 | protein disulfide isomerase family A, member 4 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PPID | peptidylprolyl isomerase D |
| RAB32 | RAB32, member RAS oncogene family |
| RFPL3 | ret finger protein-like 3 |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SEC24D | SEC24 family member D |
| SEC63 | SEC63 homolog (S. cerevisiae) |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SERP1 | stress-associated endoplasmic reticulum protein 1 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SYNM | synemin, intermediate filament protein |
| TES | testin LIM domain protein |
| TMEM50B | transmembrane protein 50B |
| TRIM2 | tripartite motif containing 2 |
| TSPYL2 | TSPY-like 2 |
| TUBA4A | tubulin, alpha 4a |
| UBB | ubiquitin B |
| UBC | ubiquitin C |
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 |
| ULBP2 | UL16 binding protein 2 |
| VWA8 | von Willebrand factor A domain containing 8 |
| WDR61 | WD repeat domain 61 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZNF165 | zinc finger protein 165 |
| ZNF227 | zinc finger protein 227 |
| ZNF451 | zinc finger protein 451 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| AFG3L2 | AFG3-like AAA ATPase 2 |
| AGO3 | argonaute RISC catalytic component 3 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| AMPD2 | adenosine monophosphate deaminase 2 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ARHGAP29 | Rho GTPase activating protein 29 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| BACE1 | beta-site APP-cleaving enzyme 1 |
| BAMBI | BMP and activin membrane-bound inhibitor |
| BYSL | bystin-like |
| C1ORF56 | chromosome 1 open reading frame 56 |
| CARM1 | coactivator-associated arginine methyltransferase 1 |
| CARS2 | cysteinyl-tRNA synthetase 2, mitochondrial (putative) |
| CCDC92 | coiled-coil domain containing 92 |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CENPB | centromere protein B, 80kDa |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| CTPS1 | CTP synthase 1 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| EFNA1 | ephrin-A1 |
| EGR3 | early growth response 3 |
| EXOC3 | exocyst complex component 3 |
| FAM216A | family with sequence similarity 216, member A |
| FAM53C | family with sequence similarity 53, member C |
| FASTKD1 | FAST kinase domains 1 |
| FBXL4 | F-box and leucine-rich repeat protein 4 |
| FOXC1 | forkhead box C1 |
| GATAD2A | GATA zinc finger domain containing 2A |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HOXC11 | homeobox C11 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IP6K2 | inositol hexakisphosphate kinase 2 |
| IRX5 | iroquois homeobox 5 |
| KLF10 | Kruppel-like factor 10 |
| MCM10 | minichromosome maintenance complex component 10 |
| MED22 | mediator complex subunit 22 |
| MID1IP1 | MID1 interacting protein 1 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MPHOSPH8 | M-phase phosphoprotein 8 |
| MRPL34 | mitochondrial ribosomal protein L34 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| MYO9A | myosin IXA |
| NABP2 | nucleic acid binding protein 2 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing |
| NARFL | nuclear prelamin A recognition factor-like |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NME7 | NME/NM23 family member 7 |
| NPY1R | neuropeptide Y receptor Y1 |
| NRIP1 | nuclear receptor interacting protein 1 |
| OPHN1 | oligophrenin 1 |
| OXR1 | oxidation resistance 1 |
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha |
| PKN1 | protein kinase N1 |
| PLK2 | polo-like kinase 2 |
| PLSCR1 | phospholipid scramblase 1 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 |
| PRKCD | protein kinase C, delta |
| PROSER1 | proline and serine rich 1 |
| RBM14 | RNA binding motif protein 14 |
| RBM15 | RNA binding motif protein 15 |
| REEP4 | receptor accessory protein 4 |
| RGS16 | regulator of G-protein signaling 16 |
| RGS19 | regulator of G-protein signaling 19 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RRP1 | ribosomal RNA processing 1 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| S100PBP | S100P binding protein |
| SACS | sacsin molecular chaperone |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SERINC5 | serine incorporator 5 |
| SETD6 | SET domain containing 6 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC2A4RG | SLC2A4 regulator |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SPATA2L | spermatogenesis associated 2-like |
| SREBF1 | sterol regulatory element binding transcription factor 1 |
| SSFA2 | sperm specific antigen 2 |
| TAF5L | TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TFRC | transferrin receptor |
| TGIF1 | TGFB-induced factor homeobox 1 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TNIP1 | TNFAIP3 interacting protein 1 |
| TRAF5 | TNF receptor-associated factor 5 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
| VRK2 | vaccinia related kinase 2 |
| WDR3 | WD repeat domain 3 |
| WRAP73 | WD repeat containing, antisense to TP73 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZBTB24 | zinc finger and BTB domain containing 24 |
| ZCCHC6 | zinc finger, CCHC domain containing 6 |
| ZFP36 | ZFP36 ring finger protein |
| ZNF692 | zinc finger protein 692 |
