| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the tanespimycin-1056 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| AKAP17A | A kinase (PRKA) anchor protein 17A |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ARMC8 | armadillo repeat containing 8 |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF2 | activating transcription factor 2 |
| ATXN1 | ataxin 1 |
| AZI2 | 5-azacytidine induced 2 |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BAG2 | BCL2-associated athanogene 2 |
| CACYBP | calcyclin binding protein |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase |
| CCNG2 | cyclin G2 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 |
| CRELD2 | cysteine-rich with EGF-like domains 2 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| EDEM2 | ER degradation enhancer, mannosidase alpha-like 2 |
| FAM49B | family with sequence similarity 49, member B |
| FGFR2 | fibroblast growth factor receptor 2 |
| FHL1 | four and a half LIM domains 1 |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FNDC3A | fibronectin type III domain containing 3A |
| FNDC3B | fibronectin type III domain containing 3B |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 |
| GLRX | glutaredoxin (thioltransferase) |
| GMDS | GDP-mannose 4,6-dehydratase |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| HSD17B7 | hydroxysteroid (17-beta) dehydrogenase 7 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HSPA13 | heat shock protein 70kDa family, member 13 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPE1 | heat shock 10kDa protein 1 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| HYOU1 | hypoxia up-regulated 1 |
| ITFG2 | integrin alpha FG-GAP repeat containing 2 |
| JMJD6 | jumonji domain containing 6 |
| KIAA0141 | KIAA0141 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LDLR | low density lipoprotein receptor |
| LMAN1 | lectin, mannose-binding, 1 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MIR22HG | MIR22 host gene |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MORC4 | MORC family CW-type zinc finger 4 |
| NAG18 | NAG18 mRNA |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NUCB2 | nucleobindin 2 |
| OSBPL1A | oxysterol binding protein-like 1A |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PDIA4 | protein disulfide isomerase family A, member 4 |
| PLA2G3 | phospholipase A2, group III |
| PPID | peptidylprolyl isomerase D |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
| RCAN1 | regulator of calcineurin 1 |
| RHOQ | ras homolog family member Q |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RPL10 | ribosomal protein L10 |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SERTAD2 | SERTA domain containing 2 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STIP1 | stress-induced phosphoprotein 1 |
| TES | testin LIM domain protein |
| TMEM50B | transmembrane protein 50B |
| TSPYL2 | TSPY-like 2 |
| UBB | ubiquitin B |
| ULBP2 | UL16 binding protein 2 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZNF165 | zinc finger protein 165 |
| ZNF227 | zinc finger protein 227 |
| ZNF266 | zinc finger protein 266 |
| ZNF85 | zinc finger protein 85 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type |
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| AEN | apoptosis enhancing nuclease |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| ATG2A | autophagy related 2A |
| BACE1 | beta-site APP-cleaving enzyme 1 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C18ORF8 | chromosome 18 open reading frame 8 |
| CCDC15 | coiled-coil domain containing 15 |
| CD3EAP | CD3e molecule, epsilon associated protein |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| COBL | cordon-bleu WH2 repeat protein |
| COCH | cochlin |
| COG4 | component of oligomeric golgi complex 4 |
| CSK | c-src tyrosine kinase |
| CSNK2A2 | casein kinase 2, alpha prime polypeptide |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| CTPS2 | CTP synthase 2 |
| DNA2 | DNA replication helicase/nuclease 2 |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DTWD1 | DTW domain containing 1 |
| EGR3 | early growth response 3 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| EPN3 | epsin 3 |
| ERF | Ets2 repressor factor |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FASTKD1 | FAST kinase domains 1 |
| FBXL4 | F-box and leucine-rich repeat protein 4 |
| FOXC1 | forkhead box C1 |
| FOXD1 | forkhead box D1 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| H2AFJ | H2A histone family, member J |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HOXC11 | homeobox C11 |
| HPS5 | Hermansky-Pudlak syndrome 5 |
| HYAL2 | hyaluronoglucosaminidase 2 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IP6K1 | inositol hexakisphosphate kinase 1 |
| IP6K2 | inositol hexakisphosphate kinase 2 |
| IRX5 | iroquois homeobox 5 |
| KLF10 | Kruppel-like factor 10 |
| KLHL21 | kelch-like family member 21 |
| LAMA3 | laminin, alpha 3 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| METTL8 | methyltransferase like 8 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MPST | mercaptopyruvate sulfurtransferase |
| MTERF3 | mitochondrial transcription termination factor 3 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NOL9 | nucleolar protein 9 |
| NPY1R | neuropeptide Y receptor Y1 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 |
| PMS1 | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
| PRKCD | protein kinase C, delta |
| PROSER1 | proline and serine rich 1 |
| PUS1 | pseudouridylate synthase 1 |
| RBM14 | RNA binding motif protein 14 |
| RGS16 | regulator of G-protein signaling 16 |
| RGS19 | regulator of G-protein signaling 19 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| ROGDI | rogdi homolog (Drosophila) |
| RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SACS | sacsin molecular chaperone |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SMAD7 | SMAD family member 7 |
| SNRNP35 | small nuclear ribonucleoprotein 35kDa (U11/U12) |
| SPATA2L | spermatogenesis associated 2-like |
| TERF2 | telomeric repeat binding factor 2 |
| TFRC | transferrin receptor |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| THAP10 | THAP domain containing 10 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) |
| TOLLIP | toll interacting protein |
| TPTE | transmembrane phosphatase with tensin homology |
| TRIM13 | tripartite motif containing 13 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| TTC13 | tetratricopeptide repeat domain 13 |
| TTLL12 | tubulin tyrosine ligase-like family member 12 |
| VRK2 | vaccinia related kinase 2 |
| ZCCHC6 | zinc finger, CCHC domain containing 6 |
| ZNF512B | zinc finger protein 512B |
| ZXDC | ZXD family zinc finger C |
