| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the tanespimycin-1064 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATP11A | ATPase, class VI, type 11A |
| AZI2 | 5-azacytidine induced 2 |
| BAG2 | BCL2-associated athanogene 2 |
| BAG3 | BCL2-associated athanogene 3 |
| BET1 | Bet1 golgi vesicular membrane trafficking protein |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
| CACFD1 | calcium channel flower domain containing 1 |
| CAP2 | CAP, adenylate cyclase-associated protein, 2 (yeast) |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCNG2 | cyclin G2 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 |
| CRELD2 | cysteine-rich with EGF-like domains 2 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DIDO1 | death inducer-obliterator 1 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 |
| EDEM2 | ER degradation enhancer, mannosidase alpha-like 2 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FNDC3B | fibronectin type III domain containing 3B |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 |
| GLRX | glutaredoxin (thioltransferase) |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| HSD17B7 | hydroxysteroid (17-beta) dehydrogenase 7 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HSPA13 | heat shock protein 70kDa family, member 13 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa |
| HYOU1 | hypoxia up-regulated 1 |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
| LDLR | low density lipoprotein receptor |
| LMAN1 | lectin, mannose-binding, 1 |
| LPIN1 | lipin 1 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MT1G | metallothionein 1G |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PDIA4 | protein disulfide isomerase family A, member 4 |
| PLA2G3 | phospholipase A2, group III |
| PPID | peptidylprolyl isomerase D |
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A |
| PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E |
| RAB8B | RAB8B, member RAS oncogene family |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit |
| RNF216 | ring finger protein 216 |
| RNF6 | ring finger protein (C3H2C3 type) 6 |
| RRBP1 | ribosome binding protein 1 |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SEC24D | SEC24 family member D |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SENP6 | SUMO1/sentrin specific peptidase 6 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 |
| SNX3 | sorting nexin 3 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STYK1 | serine/threonine/tyrosine kinase 1 |
| TDRD3 | tudor domain containing 3 |
| TES | testin LIM domain protein |
| TMEM50B | transmembrane protein 50B |
| TPP1 | tripeptidyl peptidase I |
| TRIM2 | tripartite motif containing 2 |
| TSPYL2 | TSPY-like 2 |
| ULBP2 | UL16 binding protein 2 |
| UNKL | unkempt family zinc finger-like |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
| ZNF165 | zinc finger protein 165 |
| ZNF227 | zinc finger protein 227 |
| ZNF614 | zinc finger protein 614 |
| ZNF778 | zinc finger protein 778 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type |
| ANAPC2 | anaphase promoting complex subunit 2 |
| ARHGAP12 | Rho GTPase activating protein 12 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ATG2A | autophagy related 2A |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A |
| BFAR | bifunctional apoptosis regulator |
| BTBD3 | BTB (POZ) domain containing 3 |
| C14ORF169 | chromosome 14 open reading frame 169 |
| C9ORF3 | chromosome 9 open reading frame 3 |
| CARS2 | cysteinyl-tRNA synthetase 2, mitochondrial (putative) |
| CDC45 | cell division cycle 45 |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CRIPT | cysteine-rich PDZ-binding protein |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DENND4B | DENN/MADD domain containing 4B |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| EFNA1 | ephrin-A1 |
| EGR3 | early growth response 3 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| ERF | Ets2 repressor factor |
| ESRP2 | epithelial splicing regulatory protein 2 |
| EVL | Enah/Vasp-like |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FOXC1 | forkhead box C1 |
| GALNS | galactosamine (N-acetyl)-6-sulfatase |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HINFP | histone H4 transcription factor |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IPP | intracisternal A particle-promoted polypeptide |
| IRX5 | iroquois homeobox 5 |
| KIAA0125 | KIAA0125 |
| KLF10 | Kruppel-like factor 10 |
| LAMA5 | laminin, alpha 5 |
| LMNB2 | lamin B2 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LSM2 | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| MCAT | malonyl CoA:ACP acyltransferase (mitochondrial) |
| MCM9 | minichromosome maintenance complex component 9 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing |
| NDUFAF4 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 4 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NPY1R | neuropeptide Y receptor Y1 |
| NRIP1 | nuclear receptor interacting protein 1 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PANK4 | pantothenate kinase 4 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PHACTR4 | phosphatase and actin regulator 4 |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 |
| PRKCD | protein kinase C, delta |
| PUS1 | pseudouridylate synthase 1 |
| RARS | arginyl-tRNA synthetase |
| RBM14 | RNA binding motif protein 14 |
| RGS16 | regulator of G-protein signaling 16 |
| RHOBTB1 | Rho-related BTB domain containing 1 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| RPUSD2 | RNA pseudouridylate synthase domain containing 2 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SACS | sacsin molecular chaperone |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
| SERINC5 | serine incorporator 5 |
| SHPK | sedoheptulokinase |
| SLC10A3 | solute carrier family 10, member 3 |
| SMAD7 | SMAD family member 7 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SPATA2L | spermatogenesis associated 2-like |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| SYTL2 | synaptotagmin-like 2 |
| TBC1D31 | TBC1 domain family, member 31 |
| TBCC | tubulin folding cofactor C |
| TCEAL1 | transcription elongation factor A (SII)-like 1 |
| TDRD7 | tudor domain containing 7 |
| TFRC | transferrin receptor |
| TGIF1 | TGFB-induced factor homeobox 1 |
| THAP11 | THAP domain containing 11 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) |
| TMEM159 | transmembrane protein 159 |
| TRAPPC12 | trafficking protein particle complex 12 |
| TRMT1L | tRNA methyltransferase 1 homolog (S. cerevisiae)-like |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TTLL12 | tubulin tyrosine ligase-like family member 12 |
| TULP4 | tubby like protein 4 |
| TXLNA | taxilin alpha |
| ULK1 | unc-51 like autophagy activating kinase 1 |
| WRAP73 | WD repeat containing, antisense to TP73 |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZXDC | ZXD family zinc finger C |
