| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the tanespimycin-1147 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
| APP | amyloid beta (A4) precursor protein |
| AREG | amphiregulin |
| ARIH2 | ariadne RBR E3 ubiquitin protein ligase 2 |
| BAG3 | BCL2-associated athanogene 3 |
| BCL2L1 | BCL2-like 1 |
| BCL3 | B-cell CLL/lymphoma 3 |
| BST2 | bone marrow stromal cell antigen 2 |
| CACTIN | cactin, spliceosome C complex subunit |
| CACYBP | calcyclin binding protein |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CD84 | CD84 molecule |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CEP152 | centrosomal protein 152kDa |
| CEP162 | centrosomal protein 162kDa |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CPNE7 | copine VII |
| CPTP | ceramide-1-phosphate transfer protein |
| CREM | cAMP responsive element modulator |
| CRYZ | crystallin, zeta (quinone reductase) |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| DDR1 | discoidin domain receptor tyrosine kinase 1 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| EPHA4 | EPH receptor A4 |
| F5 | coagulation factor V (proaccelerin, labile factor) |
| FAM13A | family with sequence similarity 13, member A |
| FAS | Fas cell surface death receptor |
| FCER2 | Fc fragment of IgE, low affinity II, receptor for (CD23) |
| FCHO1 | FCH domain only 1 |
| FKBP4 | FK506 binding protein 4, 59kDa |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FPR1 | formyl peptide receptor 1 |
| HIST1H2AI | histone cluster 1, H2ai |
| HLA-A | major histocompatibility complex, class I, A |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IL10RA | interleukin 10 receptor, alpha |
| IL7R | interleukin 7 receptor |
| KIAA1109 | KIAA1109 |
| KYNU | kynureninase |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
| MOB3B | MOB kinase activator 3B |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| NDE1 | nudE neurodevelopment protein 1 |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NRP1 | neuropilin 1 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PILRA | paired immunoglobin-like type 2 receptor alpha |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 |
| PMP22 | peripheral myelin protein 22 |
| POM121 | POM121 transmembrane nucleoporin |
| PPID | peptidylprolyl isomerase D |
| PPP1R16B | protein phosphatase 1, regulatory subunit 16B |
| PPP2R4 | protein phosphatase 2A activator, regulatory subunit 4 |
| PQBP1 | polyglutamine binding protein 1 |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
| PRKCA | protein kinase C, alpha |
| RANGAP1 | Ran GTPase activating protein 1 |
| RHBDF1 | rhomboid 5 homolog 1 (Drosophila) |
| SH2D2A | SH2 domain containing 2A |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SMAD1 | SMAD family member 1 |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| SPATS2L | spermatogenesis associated, serine-rich 2-like |
| SSX1 | synovial sarcoma, X breakpoint 1 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) |
| STAB2 | stabilin 2 |
| STIP1 | stress-induced phosphoprotein 1 |
| SYN2 | synapsin II |
| THBS1 | thrombospondin 1 |
| TMF1 | TATA element modulatory factor 1 |
| TMPRSS15 | transmembrane protease, serine 15 |
| UBB | ubiquitin B |
| UBOX5 | U-box domain containing 5 |
| YY2 | YY2 transcription factor |
| ZBTB17 | zinc finger and BTB domain containing 17 |
| ZKSCAN4 | zinc finger with KRAB and SCAN domains 4 |
| Symbol | Name |
|---|---|
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BRIX1 | BRX1, biogenesis of ribosomes |
| BYSL | bystin-like |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C12ORF29 | chromosome 12 open reading frame 29 |
| C14ORF169 | chromosome 14 open reading frame 169 |
| C17ORF70 | chromosome 17 open reading frame 70 |
| C5ORF28 | chromosome 5 open reading frame 28 |
| CBLL1 | Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase |
| CBR1 | carbonyl reductase 1 |
| CCDC86 | coiled-coil domain containing 86 |
| CCDC88C | coiled-coil domain containing 88C |
| CD1D | CD1d molecule |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CDK6 | cyclin-dependent kinase 6 |
| CEBPE | CCAAT/enhancer binding protein (C/EBP), epsilon |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLDN15 | claudin 15 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CRELD2 | cysteine-rich with EGF-like domains 2 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| DCAF16 | DDB1 and CUL4 associated factor 16 |
| DENND1C | DENN/MADD domain containing 1C |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) |
| DUSP2 | dual specificity phosphatase 2 |
| EFHD2 | EF-hand domain family, member D2 |
| ENDOG | endonuclease G |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
| ERF | Ets2 repressor factor |
| FHOD1 | formin homology 2 domain containing 1 |
| FKBP5 | FK506 binding protein 5 |
| GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 |
| GAR1 | GAR1 ribonucleoprotein |
| GPR22 | G protein-coupled receptor 22 |
| GTF2H4 | general transcription factor IIH, polypeptide 4, 52kDa |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HIRA | histone cell cycle regulator |
| IFITM3 | interferon induced transmembrane protein 3 |
| KLF2 | Kruppel-like factor 2 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LIAS | lipoic acid synthetase |
| LINS | lines homolog (Drosophila) |
| LMNB1 | lamin B1 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| METTL8 | methyltransferase like 8 |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MPI | mannose phosphate isomerase |
| MRPL24 | mitochondrial ribosomal protein L24 |
| MTRF1 | mitochondrial translational release factor 1 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
| NXT1 | nuclear transport factor 2-like export factor 1 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| PPAN | peter pan homolog (Drosophila) |
| PRPSAP2 | phosphoribosyl pyrophosphate synthetase-associated protein 2 |
| PTER | phosphotriesterase related |
| PUS1 | pseudouridylate synthase 1 |
| PUS7 | pseudouridylate synthase 7 (putative) |
| RAB23 | RAB23, member RAS oncogene family |
| RARS | arginyl-tRNA synthetase |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RBM38 | RNA binding motif protein 38 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| RSAD1 | radical S-adenosyl methionine domain containing 1 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SCRIB | scribbled planar cell polarity protein |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SETD6 | SET domain containing 6 |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SLC50A1 | solute carrier family 50 (sugar efflux transporter), member 1 |
| SUOX | sulfite oxidase |
| SURF2 | surfeit 2 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TERT | telomerase reverse transcriptase |
| UBIAD1 | UbiA prenyltransferase domain containing 1 |
| USP36 | ubiquitin specific peptidase 36 |
| UTP3 | UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
| WDR43 | WD repeat domain 43 |
| WDR76 | WD repeat domain 76 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF232 | zinc finger protein 232 |
| ZNF248 | zinc finger protein 248 |
| ZNF480 | zinc finger protein 480 |
| ZNF623 | zinc finger protein 623 |
| ZNF767P | zinc finger family member 767, pseudogene |
