| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the tanespimycin-1159 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| AREG | amphiregulin |
| ARHGAP25 | Rho GTPase activating protein 25 |
| ARL4C | ADP-ribosylation factor-like 4C |
| ATG12 | autophagy related 12 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| AVPI1 | arginine vasopressin-induced 1 |
| BAG3 | BCL2-associated athanogene 3 |
| BST2 | bone marrow stromal cell antigen 2 |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CACYBP | calcyclin binding protein |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CD86 | CD86 molecule |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CREM | cAMP responsive element modulator |
| CRYZ | crystallin, zeta (quinone reductase) |
| CTBP2 | C-terminal binding protein 2 |
| CTSZ | cathepsin Z |
| CYP2W1 | cytochrome P450, family 2, subfamily W, polypeptide 1 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DUSP4 | dual specificity phosphatase 4 |
| FAM13A | family with sequence similarity 13, member A |
| FAS | Fas cell surface death receptor |
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) |
| FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
| FKBP4 | FK506 binding protein 4, 59kDa |
| FLOT1 | flotillin 1 |
| G0S2 | G0/G1 switch 2 |
| GTF2IRD1 | GTF2I repeat domain containing 1 |
| GTF3C3 | general transcription factor IIIC, polypeptide 3, 102kDa |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 |
| HSPA1L | heat shock 70kDa protein 1-like |
| HSPA4 | heat shock 70kDa protein 4 |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| ICAM1 | intercellular adhesion molecule 1 |
| IL10RA | interleukin 10 receptor, alpha |
| IL18RAP | interleukin 18 receptor accessory protein |
| IL1RN | interleukin 1 receptor antagonist |
| IL7R | interleukin 7 receptor |
| INO80B | INO80 complex subunit B |
| KIAA0753 | KIAA0753 |
| KLF6 | Kruppel-like factor 6 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
| MEF2D | myocyte enhancer factor 2D |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| NDRG2 | NDRG family member 2 |
| NECAB2 | N-terminal EF-hand calcium binding protein 2 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NXF2 | nuclear RNA export factor 2 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PHACTR2 | phosphatase and actin regulator 2 |
| PHTF1 | putative homeodomain transcription factor 1 |
| PHTF2 | putative homeodomain transcription factor 2 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 |
| PPID | peptidylprolyl isomerase D |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| RAB13 | RAB13, member RAS oncogene family |
| RIPK2 | receptor-interacting serine-threonine kinase 2 |
| RNF25 | ring finger protein 25 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SEPW1 | selenoprotein W, 1 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| SPATS2L | spermatogenesis associated, serine-rich 2-like |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STIP1 | stress-induced phosphoprotein 1 |
| THBS1 | thrombospondin 1 |
| TRAF3IP3 | TRAF3 interacting protein 3 |
| UBOX5 | U-box domain containing 5 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) |
| WDR33 | WD repeat domain 33 |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| ZNF224 | zinc finger protein 224 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
| Symbol | Name |
|---|---|
| ADRB2 | adrenoceptor beta 2, surface |
| ANKRD28 | ankyrin repeat domain 28 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BRIX1 | BRX1, biogenesis of ribosomes |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C11ORF21 | chromosome 11 open reading frame 21 |
| C14ORF169 | chromosome 14 open reading frame 169 |
| C1ORF109 | chromosome 1 open reading frame 109 |
| C20ORF27 | chromosome 20 open reading frame 27 |
| CARD9 | caspase recruitment domain family, member 9 |
| CCDC25 | coiled-coil domain containing 25 |
| CCDC86 | coiled-coil domain containing 86 |
| CCDC88C | coiled-coil domain containing 88C |
| CCNJ | cyclin J |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CLSPN | claspin |
| CLTCL1 | clathrin, heavy chain-like 1 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| CSF3R | colony stimulating factor 3 receptor (granulocyte) |
| CSK | c-src tyrosine kinase |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 |
| DECR2 | 2,4-dienoyl CoA reductase 2, peroxisomal |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DPH2 | DPH2 homolog (S. cerevisiae) |
| DUSP2 | dual specificity phosphatase 2 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| ENDOG | endonuclease G |
| FHOD1 | formin homology 2 domain containing 1 |
| G6PD | glucose-6-phosphate dehydrogenase |
| GCH1 | GTP cyclohydrolase 1 |
| HRAS | Harvey rat sarcoma viral oncogene homolog |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| ITGAX | integrin, alpha X (complement component 3 receptor 4 subunit) |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) |
| MAT2A | methionine adenosyltransferase II, alpha |
| METTL1 | methyltransferase like 1 |
| METTL8 | methyltransferase like 8 |
| MICALL2 | MICAL-like 2 |
| MOSPD3 | motile sperm domain containing 3 |
| MRPL4 | mitochondrial ribosomal protein L4 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing |
| NCF1C | neutrophil cytosolic factor 1C pseudogene |
| NFE2 | nuclear factor, erythroid 2 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor |
| NXT1 | nuclear transport factor 2-like export factor 1 |
| OTUD3 | OTU deubiquitinase 3 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PGM1 | phosphoglucomutase 1 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PMM2 | phosphomannomutase 2 |
| POLR3E | polymerase (RNA) III (DNA directed) polypeptide E (80kD) |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| PUS7 | pseudouridylate synthase 7 (putative) |
| RABEPK | Rab9 effector protein with kelch motifs |
| REXO4 | REX4, RNA exonuclease 4 homolog (S. cerevisiae) |
| RNF144A | ring finger protein 144A |
| RRP1 | ribosomal RNA processing 1 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| RSAD1 | radical S-adenosyl methionine domain containing 1 |
| SCAP | SREBF chaperone |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SCRIB | scribbled planar cell polarity protein |
| SDCCAG3 | serologically defined colon cancer antigen 3 |
| SETD6 | SET domain containing 6 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 |
| SLC25A17 | solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC38A10 | solute carrier family 38, member 10 |
| SREK1IP1 | SREK1-interacting protein 1 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TERT | telomerase reverse transcriptase |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) |
| TMEM110 | transmembrane protein 110 |
| TMEM223 | transmembrane protein 223 |
| TTI1 | TELO2 interacting protein 1 |
| TUBA3C | tubulin, alpha 3c |
| UBIAD1 | UbiA prenyltransferase domain containing 1 |
| WDR3 | WD repeat domain 3 |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZNF232 | zinc finger protein 232 |
| ZNF480 | zinc finger protein 480 |
| ZNF593 | zinc finger protein 593 |
| ZSCAN5A | zinc finger and SCAN domain containing 5A |
