| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the tanespimycin-1166 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ACOX1 | acyl-CoA oxidase 1, palmitoyl |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| ALS2CL | ALS2 C-terminal like |
| ANXA6 | annexin A6 |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| APP | amyloid beta (A4) precursor protein |
| AQP9 | aquaporin 9 |
| AREG | amphiregulin |
| ATF6B | activating transcription factor 6 beta |
| ATP5C1 | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked |
| BAG3 | BCL2-associated athanogene 3 |
| BST2 | bone marrow stromal cell antigen 2 |
| CAP2 | CAP, adenylate cyclase-associated protein, 2 (yeast) |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CEP295 | centrosomal protein 295kDa |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CLN3 | ceroid-lipofuscinosis, neuronal 3 |
| COL4A2 | collagen, type IV, alpha 2 |
| CPTP | ceramide-1-phosphate transfer protein |
| CREM | cAMP responsive element modulator |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DUSP4 | dual specificity phosphatase 4 |
| ENGASE | endo-beta-N-acetylglucosaminidase |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| FAM13A | family with sequence similarity 13, member A |
| FAS | Fas cell surface death receptor |
| FCAR | Fc fragment of IgA receptor |
| FCHO1 | FCH domain only 1 |
| FKBP4 | FK506 binding protein 4, 59kDa |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FNTB | farnesyltransferase, CAAX box, beta |
| GK3P | glycerol kinase 3 pseudogene |
| GRAMD1B | GRAM domain containing 1B |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase |
| HIST1H2AG | histone cluster 1, H2ag |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 |
| HSPA2 | heat shock 70kDa protein 2 |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IDS | iduronate 2-sulfatase |
| IL10RA | interleukin 10 receptor, alpha |
| JAG1 | jagged 1 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNK10 | potassium channel, two pore domain subfamily K, member 10 |
| KIAA0753 | KIAA0753 |
| KYNU | kynureninase |
| LILRA2 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
| MOB3B | MOB kinase activator 3B |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MT1F | metallothionein 1F |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| NDE1 | nudE neurodevelopment protein 1 |
| NIPAL3 | NIPA-like domain containing 3 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PGAP1 | post-GPI attachment to proteins 1 |
| PIN4 | peptidylprolyl cis/trans isomerase, NIMA-interacting 4 |
| PLCD1 | phospholipase C, delta 1 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 |
| PMP22 | peripheral myelin protein 22 |
| PPID | peptidylprolyl isomerase D |
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
| SGPL1 | sphingosine-1-phosphate lyase 1 |
| SGSM2 | small G protein signaling modulator 2 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) |
| SKI | SKI proto-oncogene |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STIP1 | stress-induced phosphoprotein 1 |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
| THBS1 | thrombospondin 1 |
| TK2 | thymidine kinase 2, mitochondrial |
| TLR8 | toll-like receptor 8 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
| Symbol | Name |
|---|---|
| ADAM23 | ADAM metallopeptidase domain 23 |
| ADRB2 | adrenoceptor beta 2, surface |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| C5ORF30 | chromosome 5 open reading frame 30 |
| CAPN15 | calpain 15 |
| CCDC86 | coiled-coil domain containing 86 |
| CCDC88C | coiled-coil domain containing 88C |
| CCNJ | cyclin J |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CLTCL1 | clathrin, heavy chain-like 1 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| CUTC | cutC copper transporter |
| DCTPP1 | dCTP pyrophosphatase 1 |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DPAGT1 | dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) |
| DPH2 | DPH2 homolog (S. cerevisiae) |
| ECI1 | enoyl-CoA delta isomerase 1 |
| ENDOG | endonuclease G |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FANCE | Fanconi anemia, complementation group E |
| FHOD1 | formin homology 2 domain containing 1 |
| HAGH | hydroxyacylglutathione hydrolase |
| HDAC5 | histone deacetylase 5 |
| HOMER1 | homer scaffolding protein 1 |
| HRAS | Harvey rat sarcoma viral oncogene homolog |
| IMPAD1 | inositol monophosphatase domain containing 1 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KPTN | kaptin (actin binding protein) |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MCM3AP-AS1 | MCM3AP antisense RNA 1 |
| METTL1 | methyltransferase like 1 |
| METTL8 | methyltransferase like 8 |
| MICA | MHC class I polypeptide-related sequence A |
| MID1IP1 | MID1 interacting protein 1 |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MRPL24 | mitochondrial ribosomal protein L24 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NUPL2 | nucleoporin like 2 |
| NXT1 | nuclear transport factor 2-like export factor 1 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PELP1 | proline, glutamate and leucine rich protein 1 |
| PPP1R14B | protein phosphatase 1, regulatory (inhibitor) subunit 14B |
| PRAF2 | PRA1 domain family, member 2 |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| PUS1 | pseudouridylate synthase 1 |
| PUS7 | pseudouridylate synthase 7 (putative) |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RNF144A | ring finger protein 144A |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SDCCAG3 | serologically defined colon cancer antigen 3 |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 |
| SLC25A17 | solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SND1-IT1 | SND1 intronic transcript 1 |
| STRA13 | stimulated by retinoic acid 13 |
| SURF2 | surfeit 2 |
| TASP1 | taspase, threonine aspartase, 1 |
| TBL3 | transducin (beta)-like 3 |
| TCFL5 | transcription factor-like 5 (basic helix-loop-helix) |
| TCTA | T-cell leukemia translocation altered |
| TERT | telomerase reverse transcriptase |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TNF | tumor necrosis factor |
| TSLIG3A | tRNA splicing ligase complex subunit 3A |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| TUBA3C | tubulin, alpha 3c |
| USP36 | ubiquitin specific peptidase 36 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WDR3 | WD repeat domain 3 |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZDHHC18 | zinc finger, DHHC-type containing 18 |
| ZNF248 | zinc finger protein 248 |
| ZNF557 | zinc finger protein 557 |
| ZNF593 | zinc finger protein 593 |
