| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the tanespimycin-1167 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANXA6 | annexin A6 |
| APP | amyloid beta (A4) precursor protein |
| AREG | amphiregulin |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| ATP5C1 | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 |
| BAG3 | BCL2-associated athanogene 3 |
| BST2 | bone marrow stromal cell antigen 2 |
| CACYBP | calcyclin binding protein |
| CAP2 | CAP, adenylate cyclase-associated protein, 2 (yeast) |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CHPF2 | chondroitin polymerizing factor 2 |
| CREM | cAMP responsive element modulator |
| CRYZ | crystallin, zeta (quinone reductase) |
| CTSO | cathepsin O |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DUSP4 | dual specificity phosphatase 4 |
| ENGASE | endo-beta-N-acetylglucosaminidase |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| FAM13A | family with sequence similarity 13, member A |
| FAS | Fas cell surface death receptor |
| FCAR | Fc fragment of IgA receptor |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| FKBP4 | FK506 binding protein 4, 59kDa |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| GK | glycerol kinase |
| GTF2IRD1 | GTF2I repeat domain containing 1 |
| GTF3C3 | general transcription factor IIIC, polypeptide 3, 102kDa |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IDS | iduronate 2-sulfatase |
| IL10RA | interleukin 10 receptor, alpha |
| IL7R | interleukin 7 receptor |
| KYNU | kynureninase |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| MED20 | mediator complex subunit 20 |
| MOB3B | MOB kinase activator 3B |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MT1F | metallothionein 1F |
| MT1HL1 | metallothionein 1H-like 1 |
| NCOA1 | nuclear receptor coactivator 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 |
| NRP1 | neuropilin 1 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PEX26 | peroxisomal biogenesis factor 26 |
| PHTF1 | putative homeodomain transcription factor 1 |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 |
| PPID | peptidylprolyl isomerase D |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
| PTPRA | protein tyrosine phosphatase, receptor type, A |
| PYGB | phosphorylase, glycogen; brain |
| RBM5 | RNA binding motif protein 5 |
| RIN3 | Ras and Rab interactor 3 |
| RPS9 | ribosomal protein S9 |
| SCAI | suppressor of cancer cell invasion |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SELPLG | selectin P ligand |
| SH2D2A | SH2 domain containing 2A |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) |
| STIP1 | stress-induced phosphoprotein 1 |
| THBS1 | thrombospondin 1 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
| Symbol | Name |
|---|---|
| ADRB2 | adrenoceptor beta 2, surface |
| AKTIP | AKT interacting protein |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ATAD3A | ATPase family, AAA domain containing 3A |
| BYSL | bystin-like |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C12ORF29 | chromosome 12 open reading frame 29 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| CAPN15 | calpain 15 |
| CBR1 | carbonyl reductase 1 |
| CCDC86 | coiled-coil domain containing 86 |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CNNM3 | cyclin and CBS domain divalent metal cation transport mediator 3 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| DDX10 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 10 |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| EMC9 | ER membrane protein complex subunit 9 |
| ERF | Ets2 repressor factor |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FEM1C | fem-1 homolog c (C. elegans) |
| FHOD1 | formin homology 2 domain containing 1 |
| FPGS | folylpolyglutamate synthase |
| GPHN | gephyrin |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HRAS | Harvey rat sarcoma viral oncogene homolog |
| KAT2A | K(lysine) acetyltransferase 2A |
| KIAA0930 | KIAA0930 |
| KRI1 | KRI1 homolog (S. cerevisiae) |
| LAMP5 | lysosomal-associated membrane protein family, member 5 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAK16 | MAK16 homolog (S. cerevisiae) |
| MCM3AP-AS1 | MCM3AP antisense RNA 1 |
| METTL1 | methyltransferase like 1 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MMACHC | methylmalonic aciduria (cobalamin deficiency) cblC type, with homocystinuria |
| MOGS | mannosyl-oligosaccharide glucosidase |
| MOSPD3 | motile sperm domain containing 3 |
| MREG | melanoregulin |
| MRPL4 | mitochondrial ribosomal protein L4 |
| MRTO4 | mRNA turnover 4 homolog (S. cerevisiae) |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| N6AMT1 | N-6 adenine-specific DNA methyltransferase 1 (putative) |
| NIP7 | NIP7, nucleolar pre-rRNA processing protein |
| NOC4L | nucleolar complex associated 4 homolog (S. cerevisiae) |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NTHL1 | nth endonuclease III-like 1 (E. coli) |
| NXT1 | nuclear transport factor 2-like export factor 1 |
| PGRMC2 | progesterone receptor membrane component 2 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa |
| POMGNT1 | protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) |
| PRDX4 | peroxiredoxin 4 |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| PTRH2 | peptidyl-tRNA hydrolase 2 |
| PUS7 | pseudouridylate synthase 7 (putative) |
| RABEPK | Rab9 effector protein with kelch motifs |
| REXO4 | REX4, RNA exonuclease 4 homolog (S. cerevisiae) |
| RHOC | ras homolog family member C |
| RNF41 | ring finger protein 41, E3 ubiquitin protein ligase |
| RRP1 | ribosomal RNA processing 1 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SETD6 | SET domain containing 6 |
| SIL1 | SIL1 nucleotide exchange factor |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC25A32 | solute carrier family 25 (mitochondrial folate carrier), member 32 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| STRA13 | stimulated by retinoic acid 13 |
| SURF2 | surfeit 2 |
| TERT | telomerase reverse transcriptase |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TPCN1 | two pore segment channel 1 |
| TRIM52 | tripartite motif containing 52 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 |
| UBIAD1 | UbiA prenyltransferase domain containing 1 |
| UTP20 | UTP20, small subunit (SSU) processome component, homolog (yeast) |
| VSIG4 | V-set and immunoglobulin domain containing 4 |
| WASF1 | WAS protein family, member 1 |
| WDR3 | WD repeat domain 3 |
| WDR77 | WD repeat domain 77 |
| WT1-AS | WT1 antisense RNA |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing |
| ZBED8 | zinc finger, BED-type containing 8 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF248 | zinc finger protein 248 |
| ZNF580 | zinc finger protein 580 |
| ZNF593 | zinc finger protein 593 |
