| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the tanespimycin-1218 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AFAP1 | actin filament associated protein 1 |
| AGR2 | anterior gradient 2 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| APP | amyloid beta (A4) precursor protein |
| ARMC8 | armadillo repeat containing 8 |
| B9D1 | B9 protein domain 1 |
| BAG3 | BCL2-associated athanogene 3 |
| C3AR1 | complement component 3a receptor 1 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CACYBP | calcyclin binding protein |
| CAP2 | CAP, adenylate cyclase-associated protein, 2 (yeast) |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CD68 | CD68 molecule |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CEP152 | centrosomal protein 152kDa |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CPM | carboxypeptidase M |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CTGF | connective tissue growth factor |
| CTH | cystathionine gamma-lyase |
| DMBT1 | deleted in malignant brain tumors 1 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DUSP1 | dual specificity phosphatase 1 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EPS15L1 | epidermal growth factor receptor pathway substrate 15-like 1 |
| FASTKD2 | FAST kinase domains 2 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPB8 | heat shock 22kDa protein 8 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IFI44 | interferon-induced protein 44 |
| IL11 | interleukin 11 |
| IL15 | interleukin 15 |
| IL1A | interleukin 1, alpha |
| IL7R | interleukin 7 receptor |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KRT6A | keratin 6A, type II |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| MANF | mesencephalic astrocyte-derived neurotrophic factor |
| MDM1 | Mdm1 nuclear protein homolog (mouse) |
| MED6 | mediator complex subunit 6 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| NACA | nascent polypeptide-associated complex alpha subunit |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NNMT | nicotinamide N-methyltransferase |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| PDZD2 | PDZ domain containing 2 |
| PGAP1 | post-GPI attachment to proteins 1 |
| PHF14 | PHD finger protein 14 |
| POGZ | pogo transposable element with ZNF domain |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PTAFR | platelet-activating factor receptor |
| PTGES | prostaglandin E synthase |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTHLH | parathyroid hormone-like hormone |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 |
| RGS14 | regulator of G-protein signaling 14 |
| RNF216 | ring finger protein 216 |
| RPL10 | ribosomal protein L10 |
| RPL15 | ribosomal protein L15 |
| RPS9 | ribosomal protein S9 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SENP6 | SUMO1/sentrin specific peptidase 6 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMG5 | SMG5 nonsense mediated mRNA decay factor |
| STIP1 | stress-induced phosphoprotein 1 |
| STK17A | serine/threonine kinase 17a |
| SUGP1 | SURP and G patch domain containing 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM209 | transmembrane protein 209 |
| UBB | ubiquitin B |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| WDR33 | WD repeat domain 33 |
| YTHDC2 | YTH domain containing 2 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 |
| ZNF227 | zinc finger protein 227 |
| ZNF277 | zinc finger protein 277 |
| ZNF747 | zinc finger protein 747 |
| ZNF76 | zinc finger protein 76 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
| Symbol | Name |
|---|---|
| ACBD4 | acyl-CoA binding domain containing 4 |
| ADRB2 | adrenoceptor beta 2, surface |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| BMP2 | bone morphogenetic protein 2 |
| BMP4 | bone morphogenetic protein 4 |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CHKB | choline kinase beta |
| CHPF | chondroitin polymerizing factor |
| CNN2 | calponin 2 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CUEDC1 | CUE domain containing 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DENND4B | DENN/MADD domain containing 4B |
| DGKZ | diacylglycerol kinase, zeta |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| E2F8 | E2F transcription factor 8 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EFNA3 | ephrin-A3 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| FGF1 | fibroblast growth factor 1 (acidic) |
| FOSL1 | FOS-like antigen 1 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| FUZ | fuzzy planar cell polarity protein |
| GBX2 | gastrulation brain homeobox 2 |
| HECTD3 | HECT domain containing E3 ubiquitin protein ligase 3 |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HMGA2 | high mobility group AT-hook 2 |
| HOXC13 | homeobox C13 |
| IER2 | immediate early response 2 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IL32 | interleukin 32 |
| IL4R | interleukin 4 receptor |
| IRGQ | immunity-related GTPase family, Q |
| ISYNA1 | inositol-3-phosphate synthase 1 |
| KDM3A | lysine (K)-specific demethylase 3A |
| KIZ | kizuna centrosomal protein |
| LPAR3 | lysophosphatidic acid receptor 3 |
| LY6E | lymphocyte antigen 6 complex, locus E |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MICU1 | mitochondrial calcium uptake 1 |
| MYL9 | myosin, light chain 9, regulatory |
| NDE1 | nudE neurodevelopment protein 1 |
| NDRG1 | N-myc downstream regulated 1 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NSMF | NMDA receptor synaptonuclear signaling and neuronal migration factor |
| ORC1 | origin recognition complex, subunit 1 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PBX3 | pre-B-cell leukemia homeobox 3 |
| PC | pyruvate carboxylase |
| PCBP4 | poly(rC) binding protein 4 |
| PELP1 | proline, glutamate and leucine rich protein 1 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PKM | pyruvate kinase, muscle |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRR15L | proline rich 15-like |
| PSKH1 | protein serine kinase H1 |
| RAB4B | RAB4B, member RAS oncogene family |
| RBM42 | RNA binding motif protein 42 |
| RGS17 | regulator of G-protein signaling 17 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 |
| ROGDI | rogdi homolog (Drosophila) |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SCAMP5 | secretory carrier membrane protein 5 |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SF3B4 | splicing factor 3b, subunit 4, 49kDa |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| TAGLN | transgelin |
| TBC1D8B | TBC1 domain family, member 8B (with GRAM domain) |
| TEAD3 | TEA domain family member 3 |
| TMEM120B | transmembrane protein 120B |
| TMEM159 | transmembrane protein 159 |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TPCN1 | two pore segment channel 1 |
| TRIM21 | tripartite motif containing 21 |
| TRIP10 | thyroid hormone receptor interactor 10 |
| VAT1 | vesicle amine transport 1 |
| VEGFA | vascular endothelial growth factor A |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WEE1 | WEE1 G2 checkpoint kinase |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZNF408 | zinc finger protein 408 |
| ZNF574 | zinc finger protein 574 |
