| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the tanespimycin-1226 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ADAM22 | ADAM metallopeptidase domain 22 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| ARHGAP44 | Rho GTPase activating protein 44 |
| B9D1 | B9 protein domain 1 |
| BAG3 | BCL2-associated athanogene 3 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| COL4A6 | collagen, type IV, alpha 6 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CTGF | connective tissue growth factor |
| CUL5 | cullin 5 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DIDO1 | death inducer-obliterator 1 |
| DIO2 | deiodinase, iodothyronine, type II |
| DMBT1 | deleted in malignant brain tumors 1 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DUSP1 | dual specificity phosphatase 1 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa |
| ESR1 | estrogen receptor 1 |
| FBLN1 | fibulin 1 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GAS7 | growth arrest-specific 7 |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMOX1 | heme oxygenase 1 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4 | heat shock 70kDa protein 4 |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPB8 | heat shock 22kDa protein 8 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IFT27 | intraflagellar transport 27 |
| IL7R | interleukin 7 receptor |
| INO80B | INO80 complex subunit B |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KIF1A | kinesin family member 1A |
| KLHL36 | kelch-like family member 36 |
| KRT6A | keratin 6A, type II |
| LRRK1 | leucine-rich repeat kinase 1 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MANF | mesencephalic astrocyte-derived neurotrophic factor |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| NACA | nascent polypeptide-associated complex alpha subunit |
| NCAPH2 | non-SMC condensin II complex, subunit H2 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 |
| NFYA | nuclear transcription factor Y, alpha |
| NPHS2 | nephrosis 2, idiopathic, steroid-resistant (podocin) |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NUP214 | nucleoporin 214kDa |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| PDIA4 | protein disulfide isomerase family A, member 4 |
| PDZD2 | PDZ domain containing 2 |
| PGAP1 | post-GPI attachment to proteins 1 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRAMEF11 | PRAME family member 11 |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RGS10 | regulator of G-protein signaling 10 |
| RHAG | Rh-associated glycoprotein |
| RPL10 | ribosomal protein L10 |
| RPL23 | ribosomal protein L23 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SEC63 | SEC63 homolog (S. cerevisiae) |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SERHL2 | serine hydrolase-like 2 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SGSH | N-sulfoglucosamine sulfohydrolase |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| STIP1 | stress-induced phosphoprotein 1 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEM50B | transmembrane protein 50B |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UNKL | unkempt family zinc finger-like |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 |
| ZFP64 | ZFP64 zinc finger protein |
| ZNF408 | zinc finger protein 408 |
| ZNF442 | zinc finger protein 442 |
| ZNF747 | zinc finger protein 747 |
| ZNF778 | zinc finger protein 778 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
| Symbol | Name |
|---|---|
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ANAPC2 | anaphase promoting complex subunit 2 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| BLM | Bloom syndrome, RecQ helicase-like |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C9ORF114 | chromosome 9 open reading frame 114 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CDCA4 | cell division cycle associated 4 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CENPT | centromere protein T |
| CFAP44 | cilia and flagella associated protein 44 |
| CHPF | chondroitin polymerizing factor |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| CUEDC1 | CUE domain containing 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DSN1 | DSN1, MIS12 kinetochore complex component |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| E2F8 | E2F transcription factor 8 |
| EDC3 | enhancer of mRNA decapping 3 |
| EDC4 | enhancer of mRNA decapping 4 |
| EFNA3 | ephrin-A3 |
| EPPK1 | epiplakin 1 |
| ERF | Ets2 repressor factor |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ESRP2 | epithelial splicing regulatory protein 2 |
| FADS2 | fatty acid desaturase 2 |
| FAM57A | family with sequence similarity 57, member A |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FJX1 | four jointed box 1 (Drosophila) |
| FSD1 | fibronectin type III and SPRY domain containing 1 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| HDAC3 | histone deacetylase 3 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AM | histone cluster 1, H2am |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| JUNB | jun B proto-oncogene |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KIFC1 | kinesin family member C1 |
| KRT15 | keratin 15, type I |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MCM10 | minichromosome maintenance complex component 10 |
| MCOLN1 | mucolipin 1 |
| MICALL2 | MICAL-like 2 |
| MOXD1 | monooxygenase, DBH-like 1 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MXD3 | MAX dimerization protein 3 |
| NACC2 | NACC family member 2, BEN and BTB (POZ) domain containing |
| NDRG1 | N-myc downstream regulated 1 |
| ORC1 | origin recognition complex, subunit 1 |
| OVGP1 | oviductal glycoprotein 1, 120kDa |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
| PRR15L | proline rich 15-like |
| PSKH1 | protein serine kinase H1 |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RBM14 | RNA binding motif protein 14 |
| RBM15 | RNA binding motif protein 15 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SETBP1 | SET binding protein 1 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SNPH | syntaphilin |
| SOWAHC | sosondowah ankyrin repeat domain family member C |
| SPATA2L | spermatogenesis associated 2-like |
| SREK1IP1 | SREK1-interacting protein 1 |
| STAG3L1 | stromal antigen 3-like 1 (pseudogene) |
| STIM1 | stromal interaction molecule 1 |
| TBX19 | T-box 19 |
| TEAD3 | TEA domain family member 3 |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMEM104 | transmembrane protein 104 |
| TMEM156 | transmembrane protein 156 |
| TRIM21 | tripartite motif containing 21 |
| TUBB2B | tubulin, beta 2B class IIb |
| TUFT1 | tuftelin 1 |
| TXNL4B | thioredoxin-like 4B |
| ULK1 | unc-51 like autophagy activating kinase 1 |
| URM1 | ubiquitin related modifier 1 |
| USP6 | ubiquitin specific peptidase 6 |
| WASF1 | WAS protein family, member 1 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZNF143 | zinc finger protein 143 |