| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the tanespimycin-1631 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCY7 | adenylate cyclase 7 |
| ADM | adrenomedullin |
| AKAP9 | A kinase (PRKA) anchor protein 9 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| APP | amyloid beta (A4) precursor protein |
| ARG2 | arginase 2 |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| BAG2 | BCL2-associated athanogene 2 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BST2 | bone marrow stromal cell antigen 2 |
| BTN2A2 | butyrophilin, subfamily 2, member A2 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CCNG2 | cyclin G2 |
| CENPF | centromere protein F, 350/400kDa |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CORT | cortistatin |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CTH | cystathionine gamma-lyase |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DIDO1 | death inducer-obliterator 1 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| ENGASE | endo-beta-N-acetylglucosaminidase |
| FGFR2 | fibroblast growth factor receptor 2 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 |
| GLRX | glutaredoxin (thioltransferase) |
| GTF3C3 | general transcription factor IIIC, polypeptide 3, 102kDa |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HOXA10 | homeobox A10 |
| HOXA5 | homeobox A5 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HSPA13 | heat shock protein 70kDa family, member 13 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa |
| IFT27 | intraflagellar transport 27 |
| LMAN1 | lectin, mannose-binding, 1 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| LZTFL1 | leucine zipper transcription factor-like 1 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MED6 | mediator complex subunit 6 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| OSBPL1A | oxysterol binding protein-like 1A |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PDIA4 | protein disulfide isomerase family A, member 4 |
| PLA2G3 | phospholipase A2, group III |
| PPID | peptidylprolyl isomerase D |
| PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E |
| PRLR | prolactin receptor |
| PRSS16 | protease, serine, 16 (thymus) |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit |
| RCAN1 | regulator of calcineurin 1 |
| RFPL2 | ret finger protein-like 2 |
| RGS2 | regulator of G-protein signaling 2 |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| SEC24D | SEC24 family member D |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SERP1 | stress-associated endoplasmic reticulum protein 1 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SIK1 | salt-inducible kinase 1 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SSBP1 | single-stranded DNA binding protein 1, mitochondrial |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| TES | testin LIM domain protein |
| TM2D1 | TM2 domain containing 1 |
| TMEM41B | transmembrane protein 41B |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRIM2 | tripartite motif containing 2 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TSPYL4 | TSPY-like 4 |
| TUBA4A | tubulin, alpha 4a |
| TXNIP | thioredoxin interacting protein |
| ULBP2 | UL16 binding protein 2 |
| ZNF165 | zinc finger protein 165 |
| ZNF226 | zinc finger protein 226 |
| ZNF227 | zinc finger protein 227 |
| ZNF292 | zinc finger protein 292 |
| ZNF329 | zinc finger protein 329 |
| ZNF350 | zinc finger protein 350 |
| ZNF451 | zinc finger protein 451 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| ASTE1 | asteroid homolog 1 (Drosophila) |
| ATAD3A | ATPase family, AAA domain containing 3A |
| BAMBI | BMP and activin membrane-bound inhibitor |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| C12ORF4 | chromosome 12 open reading frame 4 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C9ORF3 | chromosome 9 open reading frame 3 |
| CCNE2 | cyclin E2 |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CFD | complement factor D (adipsin) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLDN4 | claudin 4 |
| CLDN9 | claudin 9 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CLSPN | claspin |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DUSP4 | dual specificity phosphatase 4 |
| EFNA1 | ephrin-A1 |
| EGR3 | early growth response 3 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| EPN3 | epsin 3 |
| ESRP2 | epithelial splicing regulatory protein 2 |
| EXO1 | exonuclease 1 |
| FAM102A | family with sequence similarity 102, member A |
| FAM65A | family with sequence similarity 65, member A |
| FANCE | Fanconi anemia, complementation group E |
| FMO4 | flavin containing monooxygenase 4 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| FZD4 | frizzled class receptor 4 |
| GPR19 | G protein-coupled receptor 19 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HOXC13 | homeobox C13 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| IFT20 | intraflagellar transport 20 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KLF10 | Kruppel-like factor 10 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| MAP6D1 | MAP6 domain containing 1 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NMU | neuromedin U |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| NXT1 | nuclear transport factor 2-like export factor 1 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PLK2 | polo-like kinase 2 |
| PMS1 | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
| PRKCD | protein kinase C, delta |
| PRMT7 | protein arginine methyltransferase 7 |
| RAB20 | RAB20, member RAS oncogene family |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RGS16 | regulator of G-protein signaling 16 |
| RGS19 | regulator of G-protein signaling 19 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| RRP1 | ribosomal RNA processing 1 |
| SCAMP4 | secretory carrier membrane protein 4 |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SETMAR | SET domain and mariner transposase fusion gene |
| SIDT1 | SID1 transmembrane family, member 1 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC37A1 | solute carrier family 37 (glucose-6-phosphate transporter), member 1 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SMAD7 | SMAD family member 7 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SPATA2L | spermatogenesis associated 2-like |
| SRGAP2 | SLIT-ROBO Rho GTPase activating protein 2 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| SYTL2 | synaptotagmin-like 2 |
| TCTA | T-cell leukemia translocation altered |
| TDRD7 | tudor domain containing 7 |
| TERF2 | telomeric repeat binding factor 2 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TIPIN | TIMELESS interacting protein |
| TMEM104 | transmembrane protein 104 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TPRA1 | transmembrane protein, adipocyte asscociated 1 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| UBIAD1 | UbiA prenyltransferase domain containing 1 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZNF354A | zinc finger protein 354A |
| ZXDC | ZXD family zinc finger C |
