| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the tanespimycin-1651 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| ADCY7 | adenylate cyclase 7 |
| ADM | adrenomedullin |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| ARG2 | arginase 2 |
| BAG2 | BCL2-associated athanogene 2 |
| BIN1 | bridging integrator 1 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase |
| CASP8 | caspase 8, apoptosis-related cysteine peptidase |
| CCDC25 | coiled-coil domain containing 25 |
| CCNG2 | cyclin G2 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CORT | cortistatin |
| CRELD1 | cysteine-rich with EGF-like domains 1 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EFNB3 | ephrin-B3 |
| FGFR2 | fibroblast growth factor receptor 2 |
| FNDC3A | fibronectin type III domain containing 3A |
| FXR1 | fragile X mental retardation, autosomal homolog 1 |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GLRX | glutaredoxin (thioltransferase) |
| GTF3C3 | general transcription factor IIIC, polypeptide 3, 102kDa |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HFE | hemochromatosis |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IL11 | interleukin 11 |
| KLHL25 | kelch-like family member 25 |
| LMAN1 | lectin, mannose-binding, 1 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor |
| MFAP3L | microfibrillar-associated protein 3-like |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NF1 | neurofibromin 1 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| OSBPL1A | oxysterol binding protein-like 1A |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLA2G3 | phospholipase A2, group III |
| PPID | peptidylprolyl isomerase D |
| PPM1E | protein phosphatase, Mg2+/Mn2+ dependent, 1E |
| PRSS16 | protease, serine, 16 (thymus) |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RCAN1 | regulator of calcineurin 1 |
| RFPL2 | ret finger protein-like 2 |
| RFPL3 | ret finger protein-like 3 |
| RGS2 | regulator of G-protein signaling 2 |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| SEC24D | SEC24 family member D |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SIK1 | salt-inducible kinase 1 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SP110 | SP110 nuclear body protein |
| SRSF5 | serine/arginine-rich splicing factor 5 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| TES | testin LIM domain protein |
| TMCO3 | transmembrane and coiled-coil domains 3 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TREX1 | three prime repair exonuclease 1 |
| TRIM2 | tripartite motif containing 2 |
| TUBA4A | tubulin, alpha 4a |
| TXNIP | thioredoxin interacting protein |
| ZNF165 | zinc finger protein 165 |
| ZNF227 | zinc finger protein 227 |
| ZNF254 | zinc finger protein 254 |
| ZNF350 | zinc finger protein 350 |
| ZNF451 | zinc finger protein 451 |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ANKRD36B | ankyrin repeat domain 36B |
| AP1G2 | adaptor-related protein complex 1, gamma 2 subunit |
| ATP13A2 | ATPase type 13A2 |
| AXIN1 | axin 1 |
| BCL2L2 | BCL2-like 2 |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| C11ORF95 | chromosome 11 open reading frame 95 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| C9ORF3 | chromosome 9 open reading frame 3 |
| CAPN15 | calpain 15 |
| CCDC15 | coiled-coil domain containing 15 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CHST7 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 |
| CISH | cytokine inducible SH2-containing protein |
| CPTP | ceramide-1-phosphate transfer protein |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa |
| DCAF16 | DDB1 and CUL4 associated factor 16 |
| DCUN1D2 | DCN1, defective in cullin neddylation 1, domain containing 2 |
| DNMBP | dynamin binding protein |
| DUSP8 | dual specificity phosphatase 8 |
| EFHD2 | EF-hand domain family, member D2 |
| EGR3 | early growth response 3 |
| ERCC8 | excision repair cross-complementation group 8 |
| FJX1 | four jointed box 1 (Drosophila) |
| FOXC1 | forkhead box C1 |
| FPGS | folylpolyglutamate synthase |
| FZD4 | frizzled class receptor 4 |
| GEMIN4 | gem (nuclear organelle) associated protein 4 |
| GPR19 | G protein-coupled receptor 19 |
| HSPBAP1 | HSPB (heat shock 27kDa) associated protein 1 |
| HTRA2 | HtrA serine peptidase 2 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IER2 | immediate early response 2 |
| INTS7 | integrator complex subunit 7 |
| IRX5 | iroquois homeobox 5 |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KLF10 | Kruppel-like factor 10 |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MCM10 | minichromosome maintenance complex component 10 |
| MID1IP1 | MID1 interacting protein 1 |
| MNX1 | motor neuron and pancreas homeobox 1 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MTCL1 | microtubule crosslinking factor 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NRIP1 | nuclear receptor interacting protein 1 |
| NUPL2 | nucleoporin like 2 |
| NXT1 | nuclear transport factor 2-like export factor 1 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PGP | phosphoglycolate phosphatase |
| PIBF1 | progesterone immunomodulatory binding factor 1 |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLD3 | phospholipase D family, member 3 |
| PMS1 | PMS1 postmeiotic segregation increased 1 (S. cerevisiae) |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PRKCD | protein kinase C, delta |
| PTCD2 | pentatricopeptide repeat domain 2 |
| RAB23 | RAB23, member RAS oncogene family |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RECQL4 | RecQ protein-like 4 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RGS16 | regulator of G-protein signaling 16 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SCAMP4 | secretory carrier membrane protein 4 |
| SCO2 | SCO2 cytochrome c oxidase assembly protein |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SETMAR | SET domain and mariner transposase fusion gene |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain |
| SLC10A3 | solute carrier family 10, member 3 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SMAD7 | SMAD family member 7 |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SPATA2L | spermatogenesis associated 2-like |
| SYTL2 | synaptotagmin-like 2 |
| TFRC | transferrin receptor |
| THOP1 | thimet oligopeptidase 1 |
| TIPIN | TIMELESS interacting protein |
| TMEM260 | transmembrane protein 260 |
| TRAPPC12 | trafficking protein particle complex 12 |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TTC13 | tetratricopeptide repeat domain 13 |
| USP18 | ubiquitin specific peptidase 18 |
| WDR76 | WD repeat domain 76 |
| ZNF239 | zinc finger protein 239 |
| ZNF331 | zinc finger protein 331 |
| ZXDC | ZXD family zinc finger C |
