| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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192 genes differentially expressed following the tanespimycin-221 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCF2 | ATP-binding cassette, sub-family F (GCN20), member 2 |
| ABHD3 | abhydrolase domain containing 3 |
| ACACA | acetyl-CoA carboxylase alpha |
| ADCY7 | adenylate cyclase 7 |
| ADGRA2 | adhesion G protein-coupled receptor A2 |
| ADM2 | adrenomedullin 2 |
| AGAP2 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 |
| AIM2 | absent in melanoma 2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 |
| ARHGAP33 | Rho GTPase activating protein 33 |
| BIN1 | bridging integrator 1 |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| BRF2 | BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit |
| C7ORF26 | chromosome 7 open reading frame 26 |
| CCDC94 | coiled-coil domain containing 94 |
| CDK10 | cyclin-dependent kinase 10 |
| CDK3 | cyclin-dependent kinase 3 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CLK1 | CDC-like kinase 1 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| DNAH3 | dynein, axonemal, heavy chain 3 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DTX3 | deltex 3, E3 ubiquitin ligase |
| DUS2 | dihydrouridine synthase 2 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 |
| EXOC7 | exocyst complex component 7 |
| FAM188A | family with sequence similarity 188, member A |
| FGFR2 | fibroblast growth factor receptor 2 |
| FUT2 | fucosyltransferase 2 (secretor status included) |
| GLMN | glomulin, FKBP associated protein |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| GRIN1 | glutamate receptor, ionotropic, N-methyl D-aspartate 1 |
| HCFC1R1 | host cell factor C1 regulator 1 (XPO1 dependent) |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HIST1H4J | histone cluster 1, H4j |
| HLA-C | major histocompatibility complex, class I, C |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IFT122 | intraflagellar transport 122 |
| ITM2A | integral membrane protein 2A |
| KLF6 | Kruppel-like factor 6 |
| KLHL18 | kelch-like family member 18 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LIAS | lipoic acid synthetase |
| MCOLN1 | mucolipin 1 |
| MINK1 | misshapen-like kinase 1 |
| MOB3B | MOB kinase activator 3B |
| MSRB2 | methionine sulfoxide reductase B2 |
| MUC1 | mucin 1, cell surface associated |
| MVK | mevalonate kinase |
| MYL10 | myosin, light chain 10, regulatory |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NUDT2 | nudix (nucleoside diphosphate linked moiety X)-type motif 2 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 |
| OCA2 | oculocutaneous albinism II |
| PAPPA2 | pappalysin 2 |
| PARVA | parvin, alpha |
| PCDHB3 | protocadherin beta 3 |
| PCDHB6 | protocadherin beta 6 |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLXNB1 | plexin B1 |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PRDM14 | PR domain containing 14 |
| RANBP10 | RAN binding protein 10 |
| RANBP3 | RAN binding protein 3 |
| RFPL2 | ret finger protein-like 2 |
| RNFT2 | ring finger protein, transmembrane 2 |
| RRAGD | Ras-related GTP binding D |
| SDC3 | syndecan 3 |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SLC28A1 | solute carrier family 28 (concentrative nucleoside transporter), member 1 |
| SLC30A5 | solute carrier family 30 (zinc transporter), member 5 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SQSTM1 | sequestosome 1 |
| TCEA2 | transcription elongation factor A (SII), 2 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) |
| TIMM44 | translocase of inner mitochondrial membrane 44 homolog (yeast) |
| TMEM161A | transmembrane protein 161A |
| TMF1 | TATA element modulatory factor 1 |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TRAK1 | trafficking protein, kinesin binding 1 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| WDR18 | WD repeat domain 18 |
| ZNF335 | zinc finger protein 335 |
| Symbol | Name |
|---|---|
| ACVR2B | activin A receptor, type IIB |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| APOLD1 | apolipoprotein L domain containing 1 |
| ASIP | agouti signaling protein |
| ATXN8OS | ATXN8 opposite strand (non-protein coding) |
| AXIN1 | axin 1 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CCDC132 | coiled-coil domain containing 132 |
| CCDC15 | coiled-coil domain containing 15 |
| CCR4 | chemokine (C-C motif) receptor 4 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD82 | CD82 molecule |
| CHRNG | cholinergic receptor, nicotinic, gamma (muscle) |
| CLEC1A | C-type lectin domain family 1, member A |
| CLIP3 | CAP-GLY domain containing linker protein 3 |
| CPA3 | carboxypeptidase A3 (mast cell) |
| CRNN | cornulin |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DCAF16 | DDB1 and CUL4 associated factor 16 |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 |
| EAF2 | ELL associated factor 2 |
| EFNA3 | ephrin-A3 |
| EFNB1 | ephrin-B1 |
| EMID1 | EMI domain containing 1 |
| EPX | eosinophil peroxidase |
| FLNC | filamin C, gamma |
| FZD4 | frizzled class receptor 4 |
| GAGE3 | G antigen 3 |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GPC3 | glypican 3 |
| GUCA2A | guanylate cyclase activator 2A (guanylin) |
| HCG9 | HLA complex group 9 (non-protein coding) |
| HOXD11 | homeobox D11 |
| HSPB3 | heat shock 27kDa protein 3 |
| HTR3B | 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic |
| HYAL3 | hyaluronoglucosaminidase 3 |
| IL36RN | interleukin 36 receptor antagonist |
| INO80D | INO80 complex subunit D |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KLHL3 | kelch-like family member 3 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LIPG | lipase, endothelial |
| LMTK1 | lemur tail kinase 1 |
| MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 |
| MAPK3 | mitogen-activated protein kinase 3 |
| MARC1 | mitochondrial amidoxime reducing component 1 |
| MFI2 | antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5 |
| MGC2889 | uncharacterized protein MGC2889 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast |
| MYOZ3 | myozenin 3 |
| NRSN2 | neurensin 2 |
| NTN1 | netrin 1 |
| NXPH3 | neurexophilin 3 |
| OR10C1 | olfactory receptor, family 10, subfamily C, member 1 (gene/pseudogene) |
| OXT | oxytocin/neurophysin I prepropeptide |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| POLD4 | polymerase (DNA-directed), delta 4, accessory subunit |
| POU5F1B | POU class 5 homeobox 1B |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PRG3 | proteoglycan 3 |
| PSG7 | pregnancy specific beta-1-glycoprotein 7 (gene/pseudogene) |
| RDH5 | retinol dehydrogenase 5 (11-cis/9-cis) |
| RNF185 | ring finger protein 185 |
| ROS1 | ROS proto-oncogene 1 , receptor tyrosine kinase |
| SCNN1G | sodium channel, non voltage gated 1 gamma subunit |
| SELL | selectin L |
| SERPINB10 | serpin peptidase inhibitor, clade B (ovalbumin), member 10 |
| SIRT2 | sirtuin 2 |
| SLC6A16 | solute carrier family 6, member 16 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| SOAT1 | sterol O-acyltransferase 1 |
| SOX21 | SRY (sex determining region Y)-box 21 |
| SPON2 | spondin 2, extracellular matrix protein |
| STAB2 | stabilin 2 |
| SYNDIG1 | synapse differentiation inducing 1 |
| SYNGR4 | synaptogyrin 4 |
| TAS2R16 | taste receptor, type 2, member 16 |
| TCN2 | transcobalamin II |
| TEX40 | testis expressed 40 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TSC22D4 | TSC22 domain family, member 4 |
| UBIAD1 | UbiA prenyltransferase domain containing 1 |
| VSIG4 | V-set and immunoglobulin domain containing 4 |
| WT1-AS | WT1 antisense RNA |
| ZNF32 | zinc finger protein 32 |
