| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the tanespimycin-2686 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AASS | aminoadipate-semialdehyde synthase |
| ABHD3 | abhydrolase domain containing 3 |
| ALPI | alkaline phosphatase, intestinal |
| ALPP | alkaline phosphatase, placental |
| ANXA1 | annexin A1 |
| ASPH | aspartate beta-hydroxylase |
| BAG3 | BCL2-associated athanogene 3 |
| BTG2 | BTG family, member 2 |
| C1ORF61 | chromosome 1 open reading frame 61 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit |
| CACYBP | calcyclin binding protein |
| CAP2 | CAP, adenylate cyclase-associated protein, 2 (yeast) |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CCL13 | chemokine (C-C motif) ligand 13 |
| CCNG2 | cyclin G2 |
| CD47 | CD47 molecule |
| CD84 | CD84 molecule |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CLU | clusterin |
| CREM | cAMP responsive element modulator |
| CRYZ | crystallin, zeta (quinone reductase) |
| DIAPH2 | diaphanous-related formin 2 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| EGOT | eosinophil granule ontogeny transcript (non-protein coding) |
| FAM149B1 | family with sequence similarity 149, member B1 |
| FAS | Fas cell surface death receptor |
| FCGR2A | Fc fragment of IgG, low affinity IIa, receptor (CD32) |
| FGG | fibrinogen gamma chain |
| FKBP4 | FK506 binding protein 4, 59kDa |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GSTA1 | glutathione S-transferase alpha 1 |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase |
| HIST1H2BJ | histone cluster 1, H2bj |
| HOXB1 | homeobox B1 |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 |
| HSPA2 | heat shock 70kDa protein 2 |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IBA57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
| IDS | iduronate 2-sulfatase |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IL1R1 | interleukin 1 receptor, type I |
| IL1R2 | interleukin 1 receptor, type II |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| LRRN2 | leucine rich repeat neuronal 2 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MUC6 | mucin 6, oligomeric mucus/gel-forming |
| NF2 | neurofibromin 2 (merlin) |
| NPTXR | neuronal pentraxin receptor |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PAK7 | p21 protein (Cdc42/Rac)-activated kinase 7 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PHACTR1 | phosphatase and actin regulator 1 |
| PHF2 | PHD finger protein 2 |
| PKNOX1 | PBX/knotted 1 homeobox 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) |
| PPID | peptidylprolyl isomerase D |
| PRELP | proline/arginine-rich end leucine-rich repeat protein |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
| PRO2964 | uncharacterized protein PRO2964 |
| RBP4 | retinol binding protein 4, plasma |
| RHBG | Rh family, B glycoprotein (gene/pseudogene) |
| RPL7 | ribosomal protein L7 |
| RUNX1 | runt-related transcription factor 1 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SFTPA2 | surfactant protein A2 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 |
| SLC35D2 | solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SNED1 | sushi, nidogen and EGF-like domains 1 |
| SOX5 | SRY (sex determining region Y)-box 5 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like |
| SPRR2B | small proline-rich protein 2B |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| STIP1 | stress-induced phosphoprotein 1 |
| TGFBR3 | transforming growth factor, beta receptor III |
| THBS1 | thrombospondin 1 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TNP2 | transition protein 2 (during histone to protamine replacement) |
| TRPC7 | transient receptor potential cation channel, subfamily C, member 7 |
| TUSC3 | tumor suppressor candidate 3 |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| Symbol | Name |
|---|---|
| ADRB2 | adrenoceptor beta 2, surface |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 |
| AP3M2 | adaptor-related protein complex 3, mu 2 subunit |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 |
| ARL15 | ADP-ribosylation factor-like 15 |
| ARPC5L | actin related protein 2/3 complex, subunit 5-like |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C1ORF35 | chromosome 1 open reading frame 35 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| C8ORF44 | chromosome 8 open reading frame 44 |
| C9ORF91 | chromosome 9 open reading frame 91 |
| CARF | calcium responsive transcription factor |
| CCDC86 | coiled-coil domain containing 86 |
| CDK20 | cyclin-dependent kinase 20 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHML | choroideremia-like (Rab escort protein 2) |
| CHST12 | carbohydrate (chondroitin 4) sulfotransferase 12 |
| CXORF56 | chromosome X open reading frame 56 |
| DOK3 | docking protein 3 |
| DUSP2 | dual specificity phosphatase 2 |
| ECI2 | enoyl-CoA delta isomerase 2 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| ENDOD1 | endonuclease domain containing 1 |
| ENDOG | endonuclease G |
| ENTPD6 | ectonucleoside triphosphate diphosphohydrolase 6 (putative) |
| EXOSC5 | exosome component 5 |
| FAM120C | family with sequence similarity 120C |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FHOD1 | formin homology 2 domain containing 1 |
| FJX1 | four jointed box 1 (Drosophila) |
| FOXN2 | forkhead box N2 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| HDHD3 | haloacid dehalogenase-like hydrolase domain containing 3 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HRAS | Harvey rat sarcoma viral oncogene homolog |
| IER2 | immediate early response 2 |
| INHBE | inhibin, beta E |
| ISOC1 | isochorismatase domain containing 1 |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| MAGEH1 | melanoma antigen family H1 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MCM3AP-AS1 | MCM3AP antisense RNA 1 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MXD3 | MAX dimerization protein 3 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NCF1C | neutrophil cytosolic factor 1C pseudogene |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NFKBIL1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NXT1 | nuclear transport factor 2-like export factor 1 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
| P2RY11 | purinergic receptor P2Y, G-protein coupled, 11 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PDZD7 | PDZ domain containing 7 |
| PGP | phosphoglycolate phosphatase |
| PRDM13 | PR domain containing 13 |
| PRR7 | proline rich 7 (synaptic) |
| PSKH1 | protein serine kinase H1 |
| PUS1 | pseudouridylate synthase 1 |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
| RGS16 | regulator of G-protein signaling 16 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| SGMS1 | sphingomyelin synthase 1 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC16A4 | solute carrier family 16, member 4 |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 |
| SLC25A22 | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 |
| SPATA2L | spermatogenesis associated 2-like |
| STC2 | stanniocalcin 2 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TCTA | T-cell leukemia translocation altered |
| TERT | telomerase reverse transcriptase |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| THEM6 | thioesterase superfamily member 6 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TMEM223 | transmembrane protein 223 |
| TNF | tumor necrosis factor |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TRIB3 | tribbles pseudokinase 3 |
| TTLL12 | tubulin tyrosine ligase-like family member 12 |
| TWISTNB | TWIST neighbor |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZNF215 | zinc finger protein 215 |
| ZNF593 | zinc finger protein 593 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
