| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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200 genes differentially expressed following the tanespimycin-432 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| AMBRA1 | autophagy/beclin-1 regulator 1 |
| ANAPC2 | anaphase promoting complex subunit 2 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 |
| ATG13 | autophagy related 13 |
| B4GALT4 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 |
| BCR | breakpoint cluster region |
| C2CD2L | C2CD2-like |
| CACYBP | calcyclin binding protein |
| CHMP4A | charged multivesicular body protein 4A |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| COL7A1 | collagen, type VII, alpha 1 |
| CPE | carboxypeptidase E |
| CRY1 | cryptochrome circadian clock 1 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| CTH | cystathionine gamma-lyase |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DFNB31 | deafness, autosomal recessive 31 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DUSP6 | dual specificity phosphatase 6 |
| EDC4 | enhancer of mRNA decapping 4 |
| ELL | elongation factor RNA polymerase II |
| ENGASE | endo-beta-N-acetylglucosaminidase |
| FLOT1 | flotillin 1 |
| GAS7 | growth arrest-specific 7 |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GM2A | GM2 ganglioside activator |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GPR107 | G protein-coupled receptor 107 |
| H2AFY2 | H2A histone family, member Y2 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4 | heat shock 70kDa protein 4 |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPE1 | heat shock 10kDa protein 1 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma |
| ITGB5 | integrin, beta 5 |
| ITSN1 | intersectin 1 (SH3 domain protein) |
| LPCAT4 | lysophosphatidylcholine acyltransferase 4 |
| MANF | mesencephalic astrocyte-derived neurotrophic factor |
| MED28 | mediator complex subunit 28 |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NOTCH1 | notch 1 |
| NSUN5P1 | NOP2/Sun domain family, member 5 pseudogene 1 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 |
| OLFML2A | olfactomedin-like 2A |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PARG | poly (ADP-ribose) glycohydrolase |
| PARVA | parvin, alpha |
| PC | pyruvate carboxylase |
| PDIA4 | protein disulfide isomerase family A, member 4 |
| PDZD2 | PDZ domain containing 2 |
| POGZ | pogo transposable element with ZNF domain |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PRDM14 | PR domain containing 14 |
| PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 |
| PTPRM | protein tyrosine phosphatase, receptor type, M |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) |
| RBKS | ribokinase |
| RNF141 | ring finger protein 141 |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SH3GL1 | SH3-domain GRB2-like 1 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 |
| SNAP23 | synaptosomal-associated protein, 23kDa |
| SP100 | SP100 nuclear antigen |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| STIP1 | stress-induced phosphoprotein 1 |
| STXBP5L | syntaxin binding protein 5-like |
| TCEA2 | transcription elongation factor A (SII), 2 |
| TIMM17A | translocase of inner mitochondrial membrane 17 homolog A (yeast) |
| TMEM50B | transmembrane protein 50B |
| TRAM1 | translocation associated membrane protein 1 |
| TRIM58 | tripartite motif containing 58 |
| TUBA4B | tubulin, alpha 4b |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 |
| USF2 | upstream transcription factor 2, c-fos interacting |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZNF142 | zinc finger protein 142 |
| ZNF358 | zinc finger protein 358 |
| ZNF839 | zinc finger protein 839 |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ADGRE1 | adhesion G protein-coupled receptor E1 |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ASIP | agouti signaling protein |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BMPR1B | bone morphogenetic protein receptor, type IB |
| BTN2A3P | butyrophilin, subfamily 2, member A3, pseudogene |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| C2CD5 | C2 calcium-dependent domain containing 5 |
| CASZ1 | castor zinc finger 1 |
| CCDC176 | coiled-coil domain containing 176 |
| CD34 | CD34 molecule |
| CD82 | CD82 molecule |
| CDH18 | cadherin 18, type 2 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CFAP70 | cilia and flagella associated protein 70 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLCA1 | chloride channel accessory 1 |
| CNTD2 | cyclin N-terminal domain containing 2 |
| COQ4 | coenzyme Q4 |
| DEFA4 | defensin, alpha 4, corticostatin |
| DKFZP586I1420 | uncharacterized protein DKFZp586I1420 |
| DRP2 | dystrophin related protein 2 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| ELAVL4 | ELAV like neuron-specific RNA binding protein 4 |
| EPX | eosinophil peroxidase |
| ERCC4 | excision repair cross-complementation group 4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM153A | family with sequence similarity 153, member A |
| FHL3 | four and a half LIM domains 3 |
| FIGF | c-fos induced growth factor (vascular endothelial growth factor D) |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GATA1 | GATA binding protein 1 (globin transcription factor 1) |
| GBAP1 | glucosidase, beta, acid pseudogene 1 |
| GBX2 | gastrulation brain homeobox 2 |
| GCKR | glucokinase (hexokinase 4) regulator |
| GK2 | glycerol kinase 2 |
| GML | glycosylphosphatidylinositol anchored molecule like |
| GMPR | guanosine monophosphate reductase |
| GRM4 | glutamate receptor, metabotropic 4 |
| HELLS | helicase, lymphoid-specific |
| HIST1H4C | histone cluster 1, H4c |
| HTR6 | 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| KLF3 | Kruppel-like factor 3 (basic) |
| LENEP | lens epithelial protein |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LOC100127972 | uncharacterized LOC100127972 |
| LUZP4 | leucine zipper protein 4 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MCHR1 | melanin-concentrating hormone receptor 1 |
| MX1 | MX dynamin-like GTPase 1 |
| MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response |
| MYOZ3 | myozenin 3 |
| NPY5R | neuropeptide Y receptor Y5 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NUBP2 | nucleotide binding protein 2 |
| OR1G1 | olfactory receptor, family 1, subfamily G, member 1 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PDE12 | phosphodiesterase 12 |
| PIGR | polymeric immunoglobulin receptor |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PKD2L1 | polycystic kidney disease 2-like 1 |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PRPH2 | peripherin 2 (retinal degeneration, slow) |
| RAB3D | RAB3D, member RAS oncogene family |
| RBM15 | RNA binding motif protein 15 |
| RIPPLY3 | ripply transcriptional repressor 3 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| SFTPA2 | surfactant protein A2 |
| SIRT2 | sirtuin 2 |
| SIX1 | SIX homeobox 1 |
| SLC17A9 | solute carrier family 17 (vesicular nucleotide transporter), member 9 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SPARCL1 | SPARC-like 1 (hevin) |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| STAT5A | signal transducer and activator of transcription 5A |
| TAAR2 | trace amine associated receptor 2 |
| TCIRG1 | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 |
| TCP11 | t-complex 11, testis-specific |
| TET3 | tet methylcytosine dioxygenase 3 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TGM3 | transglutaminase 3 |
| TMEM156 | transmembrane protein 156 |
| TMEM180 | transmembrane protein 180 |
| TMEM204 | transmembrane protein 204 |
| UBQLN4 | ubiquilin 4 |
| WDR91 | WD repeat domain 91 |
| XPA | xeroderma pigmentosum, complementation group A |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZIM2 | zinc finger, imprinted 2 |
| ZKSCAN4 | zinc finger with KRAB and SCAN domains 4 |
