| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the tanespimycin-4430 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ABCA8 | ATP-binding cassette, sub-family A (ABC1), member 8 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ADAMTS7 | ADAM metallopeptidase with thrombospondin type 1 motif, 7 |
| ADCY7 | adenylate cyclase 7 |
| ADD2 | adducin 2 (beta) |
| AFF3 | AF4/FMR2 family, member 3 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| AKR1C4 | aldo-keto reductase family 1, member C4 |
| ALDOB | aldolase B, fructose-bisphosphate |
| ANGEL2 | angel homolog 2 (Drosophila) |
| ARHGAP28 | Rho GTPase activating protein 28 |
| ARTN | artemin |
| BACH1 | BTB and CNC homology 1, basic leucine zipper transcription factor 1 |
| BEGAIN | brain-enriched guanylate kinase-associated |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CRY2 | cryptochrome circadian clock 2 |
| CTH | cystathionine gamma-lyase |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DSCAM | Down syndrome cell adhesion molecule |
| DUSP1 | dual specificity phosphatase 1 |
| EDN1 | endothelin 1 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) |
| FAS | Fas cell surface death receptor |
| FBN2 | fibrillin 2 |
| FLOT1 | flotillin 1 |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GSTM5 | glutathione S-transferase mu 5 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HFE | hemochromatosis |
| HIST1H3E | histone cluster 1, H3e |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPB8 | heat shock 22kDa protein 8 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IL11 | interleukin 11 |
| IL7R | interleukin 7 receptor |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KERA | keratocan |
| KRT6A | keratin 6A, type II |
| LCK | LCK proto-oncogene, Src family tyrosine kinase |
| LDB2 | LIM domain binding 2 |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| MED16 | mediator complex subunit 16 |
| MEG3 | maternally expressed 3 (non-protein coding) |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| NF1 | neurofibromin 1 |
| NOP16 | NOP16 nucleolar protein |
| NOX1 | NADPH oxidase 1 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NPTX2 | neuronal pentraxin II |
| OLFM1 | olfactomedin 1 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| OXTR | oxytocin receptor |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PDZD2 | PDZ domain containing 2 |
| PLD1 | phospholipase D1, phosphatidylcholine-specific |
| PLK3 | polo-like kinase 3 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| PRAF2 | PRA1 domain family, member 2 |
| PTAFR | platelet-activating factor receptor |
| PTCH1 | patched 1 |
| PTPRR | protein tyrosine phosphatase, receptor type, R |
| RAB36 | RAB36, member RAS oncogene family |
| RBM34 | RNA binding motif protein 34 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RFPL2 | ret finger protein-like 2 |
| RUNX1 | runt-related transcription factor 1 |
| RUNX1T1 | runt-related transcription factor 1; translocated to, 1 (cyclin D-related) |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SH3BP2 | SH3-domain binding protein 2 |
| SLAMF7 | SLAM family member 7 |
| SLC10A1 | solute carrier family 10 (sodium/bile acid cotransporter), member 1 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC18A1 | solute carrier family 18 (vesicular monoamine transporter), member 1 |
| SLC2A11 | solute carrier family 2 (facilitated glucose transporter), member 11 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 |
| SPRR2B | small proline-rich protein 2B |
| STC1 | stanniocalcin 1 |
| STK17B | serine/threonine kinase 17b |
| TGFB2 | transforming growth factor, beta 2 |
| TGM2 | transglutaminase 2 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| UNKL | unkempt family zinc finger-like |
| VPS9D1 | VPS9 domain containing 1 |
| ZNF277 | zinc finger protein 277 |
| ZNF518A | zinc finger protein 518A |
| Symbol | Name |
|---|---|
| ACBD4 | acyl-CoA binding domain containing 4 |
| ADGRF1 | adhesion G protein-coupled receptor F1 |
| AHDC1 | AT hook, DNA binding motif, containing 1 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARL15 | ADP-ribosylation factor-like 15 |
| ARRB2 | arrestin, beta 2 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BEND5 | BEN domain containing 5 |
| BEX1 | brain expressed, X-linked 1 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CASP8AP2 | caspase 8 associated protein 2 |
| CCNE1 | cyclin E1 |
| CCNE2 | cyclin E2 |
| CDC25A | cell division cycle 25A |
| CDC7 | cell division cycle 7 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CFAP44 | cilia and flagella associated protein 44 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| COBL | cordon-bleu WH2 repeat protein |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| DDN | dendrin |
| DSN1 | DSN1, MIS12 kinetochore complex component |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| E2F8 | E2F transcription factor 8 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) |
| ENO2 | enolase 2 (gamma, neuronal) |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| FA2H | fatty acid 2-hydroxylase |
| FAM105A | family with sequence similarity 105, member A |
| FAM131B | family with sequence similarity 131, member B |
| FAM184A | family with sequence similarity 184, member A |
| FANCF | Fanconi anemia, complementation group F |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GPR3 | G protein-coupled receptor 3 |
| GRB7 | growth factor receptor-bound protein 7 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| HILPDA | hypoxia inducible lipid droplet-associated |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AM | histone cluster 1, H2am |
| HIST1H4C | histone cluster 1, H4c |
| HOXA10 | homeobox A10 |
| HOXA6 | homeobox A6 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IL17RB | interleukin 17 receptor B |
| INO80D | INO80 complex subunit D |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KIAA1462 | KIAA1462 |
| KLF10 | Kruppel-like factor 10 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| MAT2A | methionine adenosyltransferase II, alpha |
| MCM10 | minichromosome maintenance complex component 10 |
| MCTP2 | multiple C2 domains, transmembrane 2 |
| MGP | matrix Gla protein |
| MMD | monocyte to macrophage differentiation-associated |
| NARFL | nuclear prelamin A recognition factor-like |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NXPH4 | neurexophilin 4 |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit |
| PCBP4 | poly(rC) binding protein 4 |
| PCF11 | PCF11 cleavage and polyadenylation factor subunit |
| PER3 | period circadian clock 3 |
| PLA1A | phospholipase A1 member A |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| RBM4B | RNA binding motif protein 4B |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| SCAI | suppressor of cancer cell invasion |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SOBP | sine oculis binding protein homolog (Drosophila) |
| STAC | SH3 and cysteine rich domain |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TEAD3 | TEA domain family member 3 |
| THAP10 | THAP domain containing 10 |
| TMEM156 | transmembrane protein 156 |
| TMEM180 | transmembrane protein 180 |
| TNFSF15 | tumor necrosis factor (ligand) superfamily, member 15 |
| TRAIP | TRAF interacting protein |
| TRIB2 | tribbles pseudokinase 2 |
| TRIM9 | tripartite motif containing 9 |
| TUBB2B | tubulin, beta 2B class IIb |
| UNG | uracil-DNA glycosylase |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF652 | zinc finger protein 652 |
| ZNF667 | zinc finger protein 667 |
| ZNF862 | zinc finger protein 862 |
| ZXDC | ZXD family zinc finger C |
