| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
197 genes differentially expressed following the tanespimycin-4442 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ADCY7 | adenylate cyclase 7 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| BEGAIN | brain-enriched guanylate kinase-associated |
| C14ORF132 | chromosome 14 open reading frame 132 |
| CBS | cystathionine-beta-synthase |
| CELSR3 | cadherin, EGF LAG seven-pass G-type receptor 3 |
| CEP152 | centrosomal protein 152kDa |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CPEB1 | cytoplasmic polyadenylation element binding protein 1 |
| CPZ | carboxypeptidase Z |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CRY2 | cryptochrome circadian clock 2 |
| DFNB31 | deafness, autosomal recessive 31 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DSCC1 | DNA replication and sister chromatid cohesion 1 |
| DUSP1 | dual specificity phosphatase 1 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| ENG | endoglin |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FAS | Fas cell surface death receptor |
| FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) |
| FOXG1 | forkhead box G1 |
| FRS3 | fibroblast growth factor receptor substrate 3 |
| FUT2 | fucosyltransferase 2 (secretor status included) |
| GAB1 | GRB2-associated binding protein 1 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type |
| GFER | growth factor, augmenter of liver regeneration |
| GLYR1 | glyoxylate reductase 1 homolog (Arabidopsis) |
| GMPR | guanosine monophosphate reductase |
| GRAMD1B | GRAM domain containing 1B |
| HMG20B | high mobility group 20B |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HPCAL4 | hippocalcin like 4 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPB8 | heat shock 22kDa protein 8 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IFI44 | interferon-induced protein 44 |
| IL11 | interleukin 11 |
| IL7R | interleukin 7 receptor |
| ITPK1 | inositol-tetrakisphosphate 1-kinase |
| KDR | kinase insert domain receptor |
| KRT6A | keratin 6A, type II |
| KSR1 | kinase suppressor of ras 1 |
| LMO7 | LIM domain 7 |
| MAGEA5 | melanoma antigen family A5 |
| MEG3 | maternally expressed 3 (non-protein coding) |
| NF1 | neurofibromin 1 |
| NFIB | nuclear factor I/B |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| OLFM1 | olfactomedin 1 |
| OR3A3 | olfactory receptor, family 3, subfamily A, member 3 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| OXTR | oxytocin receptor |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PCDH17 | protocadherin 17 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDZD2 | PDZ domain containing 2 |
| PF4 | platelet factor 4 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLK3 | polo-like kinase 3 |
| PMCHL1 | pro-melanin-concentrating hormone-like 1, pseudogene |
| POU6F1 | POU class 6 homeobox 1 |
| PRAMEF10 | PRAME family member 10 |
| PRKCA | protein kinase C, alpha |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPRR | protein tyrosine phosphatase, receptor type, R |
| RAB36 | RAB36, member RAS oncogene family |
| RBM17 | RNA binding motif protein 17 |
| REEP1 | receptor accessory protein 1 |
| RFPL2 | ret finger protein-like 2 |
| RGCC | regulator of cell cycle |
| RGS4 | regulator of G-protein signaling 4 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SLC12A7 | solute carrier family 12 (potassium/chloride transporter), member 7 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
| SYNPO | synaptopodin |
| SYT2 | synaptotagmin II |
| TAF7L | TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TGFB2 | transforming growth factor, beta 2 |
| TGM2 | transglutaminase 2 |
| TLN2 | talin 2 |
| TM2D1 | TM2 domain containing 1 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TRO | trophinin |
| UNKL | unkempt family zinc finger-like |
| UST | uronyl-2-sulfotransferase |
| ZNF334 | zinc finger protein 334 |
| ZNF778 | zinc finger protein 778 |
| Symbol | Name |
|---|---|
| AFF4 | AF4/FMR2 family, member 4 |
| AK5 | adenylate kinase 5 |
| ALPK1 | alpha-kinase 1 |
| AMDHD2 | amidohydrolase domain containing 2 |
| ARHGAP10 | Rho GTPase activating protein 10 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ATAD5 | ATPase family, AAA domain containing 5 |
| BEX1 | brain expressed, X-linked 1 |
| BMP4 | bone morphogenetic protein 4 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C17ORF53 | chromosome 17 open reading frame 53 |
| CAPN5 | calpain 5 |
| CCNE2 | cyclin E2 |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CLIC3 | chloride intracellular channel 3 |
| COL9A3 | collagen, type IX, alpha 3 |
| CTSF | cathepsin F |
| CYP2R1 | cytochrome P450, family 2, subfamily R, polypeptide 1 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| E2F8 | E2F transcription factor 8 |
| EFNA4 | ephrin-A4 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| EPN3 | epsin 3 |
| EPPK1 | epiplakin 1 |
| ERCC4 | excision repair cross-complementation group 4 |
| ETV6 | ets variant 6 |
| FAM131B | family with sequence similarity 131, member B |
| FAM188A | family with sequence similarity 188, member A |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| FMO4 | flavin containing monooxygenase 4 |
| GAS8 | growth arrest-specific 8 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GBX2 | gastrulation brain homeobox 2 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRB7 | growth factor receptor-bound protein 7 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H1E | histone cluster 1, H1e |
| HIST1H4C | histone cluster 1, H4c |
| HMGA2 | high mobility group AT-hook 2 |
| HOXA4 | homeobox A4 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| INCENP | inner centromere protein antigens 135/155kDa |
| INO80D | INO80 complex subunit D |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KDM4D | lysine (K)-specific demethylase 4D |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MCM10 | minichromosome maintenance complex component 10 |
| MTA2 | metastasis associated 1 family, member 2 |
| NAT6 | N-acetyltransferase 6 (GCN5-related) |
| NCALD | neurocalcin delta |
| NRTN | neurturin |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) |
| PGPEP1 | pyroglutamyl-peptidase I |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) |
| PRR15L | proline rich 15-like |
| RAB26 | RAB26, member RAS oncogene family |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| SCD5 | stearoyl-CoA desaturase 5 |
| SIRAL2 | SIR2 antiphage like 2 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC25A28 | solute carrier family 25 (mitochondrial iron transporter), member 28 |
| SNHG3 | small nucleolar RNA host gene 3 |
| SPATA2L | spermatogenesis associated 2-like |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SYT17 | synaptotagmin XVII |
| TBC1D8B | TBC1 domain family, member 8B (with GRAM domain) |
| TLR1 | toll-like receptor 1 |
| TMEM156 | transmembrane protein 156 |
| TRIM9 | tripartite motif containing 9 |
| TUBA4B | tubulin, alpha 4b |
| TXK | TXK tyrosine kinase |
| VGLL3 | vestigial-like family member 3 |
| WDR76 | WD repeat domain 76 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF428 | zinc finger protein 428 |
| ZNF652 | zinc finger protein 652 |
| ZNF671 | zinc finger protein 671 |
| ZNF862 | zinc finger protein 862 |
| ZXDC | ZXD family zinc finger C |
