| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the tanespimycin-4449 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ABHD3 | abhydrolase domain containing 3 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ADCY7 | adenylate cyclase 7 |
| ARG2 | arginase 2 |
| ARMC8 | armadillo repeat containing 8 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| BCL2A1 | BCL2-related protein A1 |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| C11ORF73 | chromosome 11 open reading frame 73 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDK20 | cyclin-dependent kinase 20 |
| CLDN1 | claudin 1 |
| CNTNAP3B | contactin associated protein-like 3B |
| COL17A1 | collagen, type XVII, alpha 1 |
| CSNK1G1 | casein kinase 1, gamma 1 |
| CTH | cystathionine gamma-lyase |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 |
| DUSP1 | dual specificity phosphatase 1 |
| EDN1 | endothelin 1 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EGF | epidermal growth factor |
| ESR1 | estrogen receptor 1 |
| EVI2A | ecotropic viral integration site 2A |
| EYA4 | EYA transcriptional coactivator and phosphatase 4 |
| FBN2 | fibrillin 2 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| GRAMD1B | GRAM domain containing 1B |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HDAC6 | histone deacetylase 6 |
| HMOX1 | heme oxygenase 1 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HOXC4 | homeobox C4 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPB8 | heat shock 22kDa protein 8 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IFI44 | interferon-induced protein 44 |
| IGF1R | insulin-like growth factor 1 receptor |
| IL11 | interleukin 11 |
| IL15 | interleukin 15 |
| IL6ST | interleukin 6 signal transducer |
| IL7R | interleukin 7 receptor |
| INSL4 | insulin-like 4 (placenta) |
| KCNIP1 | Kv channel interacting protein 1 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KRT6A | keratin 6A, type II |
| MAP1B | microtubule-associated protein 1B |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MSL3 | male-specific lethal 3 homolog (Drosophila) |
| NACA | nascent polypeptide-associated complex alpha subunit |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFIB | nuclear factor I/B |
| NMT2 | N-myristoyltransferase 2 |
| NTF3 | neurotrophin 3 |
| NUDT4 | nudix (nucleoside diphosphate linked moiety X)-type motif 4 |
| OLFM1 | olfactomedin 1 |
| OPCML | opioid binding protein/cell adhesion molecule-like |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| OXTR | oxytocin receptor |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDZD2 | PDZ domain containing 2 |
| PER2 | period circadian clock 2 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PTN | pleiotrophin |
| PTPRR | protein tyrosine phosphatase, receptor type, R |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAB30 | RAB30, member RAS oncogene family |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RFPL2 | ret finger protein-like 2 |
| RGS4 | regulator of G-protein signaling 4 |
| RHEB | Ras homolog enriched in brain |
| SAT1 | spermidine/spermine N1-acetyltransferase 1 |
| SCN8A | sodium channel, voltage gated, type VIII alpha subunit |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SPOCK3 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 |
| STK17B | serine/threonine kinase 17b |
| SYNPO | synaptopodin |
| TBL1Y | transducin (beta)-like 1, Y-linked |
| TEF | thyrotrophic embryonic factor |
| TGFB2 | transforming growth factor, beta 2 |
| TGM2 | transglutaminase 2 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| UNKL | unkempt family zinc finger-like |
| WDR33 | WD repeat domain 33 |
| WHSC1L1 | Wolf-Hirschhorn syndrome candidate 1-like 1 |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZKSCAN8 | zinc finger with KRAB and SCAN domains 8 |
| Symbol | Name |
|---|---|
| ACBD4 | acyl-CoA binding domain containing 4 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BBC3 | BCL2 binding component 3 |
| BEND5 | BEN domain containing 5 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C1S | complement component 1, s subcomponent |
| C6ORF47 | chromosome 6 open reading frame 47 |
| CACNB3 | calcium channel, voltage-dependent, beta 3 subunit |
| CBX8 | chromobox homolog 8 |
| CCNE1 | cyclin E1 |
| CCNE2 | cyclin E2 |
| CD82 | CD82 molecule |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CHAF1B | chromatin assembly factor 1, subunit B (p60) |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| COL9A3 | collagen, type IX, alpha 3 |
| CRLF1 | cytokine receptor-like factor 1 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| ENO3 | enolase 3 (beta, muscle) |
| EPN3 | epsin 3 |
| FBRS | fibrosin |
| FBXO2 | F-box protein 2 |
| FBXW4P1 | F-box and WD repeat domain containing 4 pseudogene 1 |
| FMO4 | flavin containing monooxygenase 4 |
| GALK1 | galactokinase 1 |
| GBX2 | gastrulation brain homeobox 2 |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GRB7 | growth factor receptor-bound protein 7 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HHLA1 | HERV-H LTR-associating 1 |
| HIST1H2BN | histone cluster 1, H2bn |
| HIST1H4D | histone cluster 1, H4d |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HOXA2 | homeobox A2 |
| HOXA7 | homeobox A7 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IFNA14 | interferon, alpha 14 |
| IL4R | interleukin 4 receptor |
| JUNB | jun B proto-oncogene |
| KIAA0319L | KIAA0319-like |
| LEFTY1 | left-right determination factor 1 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LMTK1 | lemur tail kinase 1 |
| LRRC61 | leucine rich repeat containing 61 |
| MAGEF1 | melanoma antigen family F1 |
| MCM10 | minichromosome maintenance complex component 10 |
| MCOLN3 | mucolipin 3 |
| MN1 | meningioma (disrupted in balanced translocation) 1 |
| MRAS | muscle RAS oncogene homolog |
| MXD3 | MAX dimerization protein 3 |
| NCALD | neurocalcin delta |
| NEUROD4 | neuronal differentiation 4 |
| NRG2 | neuregulin 2 |
| OLFML2A | olfactomedin-like 2A |
| ORC1 | origin recognition complex, subunit 1 |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PAQR5 | progestin and adipoQ receptor family member V |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PLA1A | phospholipase A1 member A |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PRR15L | proline rich 15-like |
| RAB3A | RAB3A, member RAS oncogene family |
| RANBP17 | RAN binding protein 17 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RPA4 | replication protein A4, 30kDa |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC34A2 | solute carrier family 34 (type II sodium/phosphate cotransporter), member 2 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SMO | smoothened, frizzled class receptor |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| TAGLN | transgelin |
| TGFBI | transforming growth factor, beta-induced, 68kDa |
| TMEM206 | transmembrane protein 206 |
| TRIM25 | tripartite motif containing 25 |
| TRIM45 | tripartite motif containing 45 |
| TRIM9 | tripartite motif containing 9 |
| USB1 | U6 snRNA biogenesis 1 |
| VN1R1 | vomeronasal 1 receptor 1 |
| WDR25 | WD repeat domain 25 |
| WDR62 | WD repeat domain 62 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| YY2 | YY2 transcription factor |
| ZNF155 | zinc finger protein 155 |
| ZNF214 | zinc finger protein 214 |
| ZNF280B | zinc finger protein 280B |
| ZNF606 | zinc finger protein 606 |
| ZNF639 | zinc finger protein 639 |
| ZNF862 | zinc finger protein 862 |
