| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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195 genes differentially expressed following the tanespimycin-4450 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTC1 | actin, alpha, cardiac muscle 1 |
| ADCY7 | adenylate cyclase 7 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| ATP6AP2 | ATPase, H+ transporting, lysosomal accessory protein 2 |
| BAAT | bile acid CoA:amino acid N-acyltransferase |
| BLZF1 | basic leucine zipper nuclear factor 1 |
| CCR5 | chemokine (C-C motif) receptor 5 (gene/pseudogene) |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) |
| CD22 | CD22 molecule |
| CD52 | CD52 molecule |
| CDK20 | cyclin-dependent kinase 20 |
| CLCN7 | chloride channel, voltage-sensitive 7 |
| CLSTN3 | calsyntenin 3 |
| COL17A1 | collagen, type XVII, alpha 1 |
| COL3A1 | collagen, type III, alpha 1 |
| CPZ | carboxypeptidase Z |
| CTH | cystathionine gamma-lyase |
| DMBT1 | deleted in malignant brain tumors 1 |
| DMRT1 | doublesex and mab-3 related transcription factor 1 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DUSP1 | dual specificity phosphatase 1 |
| EDRF1 | erythroid differentiation regulatory factor 1 |
| EFHC2 | EF-hand domain (C-terminal) containing 2 |
| FBN2 | fibrillin 2 |
| FBXO21 | F-box protein 21 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type |
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GRAMD1B | GRAM domain containing 1B |
| GVINP1 | GTPase, very large interferon inducible pseudogene 1 |
| HFE | hemochromatosis |
| HMOX1 | heme oxygenase 1 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HOXC4 | homeobox C4 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPB8 | heat shock 22kDa protein 8 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase |
| ICAM1 | intercellular adhesion molecule 1 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IDS | iduronate 2-sulfatase |
| IL11 | interleukin 11 |
| IL6ST | interleukin 6 signal transducer |
| IL7R | interleukin 7 receptor |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KRT6A | keratin 6A, type II |
| LRRK1 | leucine-rich repeat kinase 1 |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MTMR1 | myotubularin related protein 1 |
| MUC8 | mucin 8 |
| MYBPC3 | myosin binding protein C, cardiac |
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFIB | nuclear factor I/B |
| NRF1 | nuclear respiratory factor 1 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| OXTR | oxytocin receptor |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PDZD2 | PDZ domain containing 2 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| POU5F1B | POU class 5 homeobox 1B |
| PRDM1 | PR domain containing 1, with ZNF domain |
| PRKCE | protein kinase C, epsilon |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PTN | pleiotrophin |
| PTPRR | protein tyrosine phosphatase, receptor type, R |
| RASAL2 | RAS protein activator like 2 |
| RFPL2 | ret finger protein-like 2 |
| RGCC | regulator of cell cycle |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SLN | sarcolipin |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SYNPO | synaptopodin |
| TBCD | tubulin folding cofactor D |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TGFB2 | transforming growth factor, beta 2 |
| THSD4 | thrombospondin, type I, domain containing 4 |
| TMEFF1 | transmembrane protein with EGF-like and two follistatin-like domains 1 |
| TPR | translocated promoter region, nuclear basket protein |
| WDR33 | WD repeat domain 33 |
| WSB1 | WD repeat and SOCS box containing 1 |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| ZNF362 | zinc finger protein 362 |
| Symbol | Name |
|---|---|
| ABHD8 | abhydrolase domain containing 8 |
| ADGRB2 | adhesion G protein-coupled receptor B2 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ASIC3 | acid sensing (proton gated) ion channel 3 |
| BMP4 | bone morphogenetic protein 4 |
| C11ORF68 | chromosome 11 open reading frame 68 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| CAPN5 | calpain 5 |
| CCNE1 | cyclin E1 |
| CCNE2 | cyclin E2 |
| CDC25A | cell division cycle 25A |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CENPT | centromere protein T |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CNGA1 | cyclic nucleotide gated channel alpha 1 |
| CNTN1 | contactin 1 |
| DDN | dendrin |
| DEPDC5 | DEP domain containing 5 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| E2F8 | E2F transcription factor 8 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EPN3 | epsin 3 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| GAS8 | growth arrest-specific 8 |
| GBX2 | gastrulation brain homeobox 2 |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| GRB7 | growth factor receptor-bound protein 7 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HAS2 | hyaluronan synthase 2 |
| HDAC11 | histone deacetylase 11 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIST1H3H | histone cluster 1, H3h |
| HOXA4 | homeobox A4 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| IFI44L | interferon-induced protein 44-like |
| IQCG | IQ motif containing G |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| ITPKA | inositol-trisphosphate 3-kinase A |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KIAA1107 | KIAA1107 |
| KLHL36 | kelch-like family member 36 |
| MCC | mutated in colorectal cancers |
| NCALD | neurocalcin delta |
| NXPH4 | neurexophilin 4 |
| ORC1 | origin recognition complex, subunit 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PEX26 | peroxisomal biogenesis factor 26 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PLA1A | phospholipase A1 member A |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| POLM | polymerase (DNA directed), mu |
| PQLC2 | PQ loop repeat containing 2 |
| PRKG2 | protein kinase, cGMP-dependent, type II |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
| RIBC2 | RIB43A domain with coiled-coils 2 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| SCARA3 | scavenger receptor class A, member 3 |
| SCIN | scinderin |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLC38A10 | solute carrier family 38, member 10 |
| SLC4A3 | solute carrier family 4 (anion exchanger), member 3 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SMO | smoothened, frizzled class receptor |
| SP1 | Sp1 transcription factor |
| SPAG4 | sperm associated antigen 4 |
| SPATA2L | spermatogenesis associated 2-like |
| SSBP3 | single stranded DNA binding protein 3 |
| STON1 | stonin 1 |
| TMEM206 | transmembrane protein 206 |
| TRIM25 | tripartite motif containing 25 |
| TRIM9 | tripartite motif containing 9 |
| WDR25 | WD repeat domain 25 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZFHX3 | zinc finger homeobox 3 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF107 | zinc finger protein 107 |
| ZNF137P | zinc finger protein 137, pseudogene |
| ZNF141 | zinc finger protein 141 |
| ZNF862 | zinc finger protein 862 |
| ZXDC | ZXD family zinc finger C |
