| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
199 genes differentially expressed following the tanespimycin-450 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) |
| AFF1 | AF4/FMR2 family, member 1 |
| AHCYL2 | adenosylhomocysteinase-like 2 |
| AHSA1 | AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) |
| AKAP9 | A kinase (PRKA) anchor protein 9 |
| AMBRA1 | autophagy/beclin-1 regulator 1 |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| BAG3 | BCL2-associated athanogene 3 |
| BRE | brain and reproductive organ-expressed (TNFRSF1A modulator) |
| CACYBP | calcyclin binding protein |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase |
| CCNG2 | cyclin G2 |
| CCR5 | chemokine (C-C motif) receptor 5 (gene/pseudogene) |
| CD2BP2 | CD2 (cytoplasmic tail) binding protein 2 |
| CD5 | CD5 molecule |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CIITA | class II, major histocompatibility complex, transactivator |
| CLU | clusterin |
| CPOX | coproporphyrinogen oxidase |
| CREB3L1 | cAMP responsive element binding protein 3-like 1 |
| CTH | cystathionine gamma-lyase |
| CUL4B | cullin 4B |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DXO | decapping exoribonuclease |
| E2F5 | E2F transcription factor 5, p130-binding |
| EGFR | epidermal growth factor receptor |
| EID1 | EP300 interacting inhibitor of differentiation 1 |
| EML2 | echinoderm microtubule associated protein like 2 |
| ENGASE | endo-beta-N-acetylglucosaminidase |
| FAM222B | family with sequence similarity 222, member B |
| FBXO38 | F-box protein 38 |
| FKBP4 | FK506 binding protein 4, 59kDa |
| FOXA2 | forkhead box A2 |
| GLRA2 | glycine receptor, alpha 2 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) |
| GRK5 | G protein-coupled receptor kinase 5 |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIBCH | 3-hydroxyisobutyryl-CoA hydrolase |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA4L | heat shock 70kDa protein 4-like |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPB1 | heat shock 27kDa protein 1 |
| HSPB11 | heat shock protein family B (small), member 11 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| HYOU1 | hypoxia up-regulated 1 |
| IFRD1 | interferon-related developmental regulator 1 |
| IL19 | interleukin 19 |
| IL7R | interleukin 7 receptor |
| KIAA0513 | KIAA0513 |
| KIF23 | kinesin family member 23 |
| KTN1 | kinectin 1 (kinesin receptor) |
| LAMP2 | lysosomal-associated membrane protein 2 |
| LUZP1 | leucine zipper protein 1 |
| MBNL2 | muscleblind-like splicing regulator 2 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NOTCH1 | notch 1 |
| NPY1R | neuropeptide Y receptor Y1 |
| NUCB2 | nucleobindin 2 |
| PDIA4 | protein disulfide isomerase family A, member 4 |
| PDZD2 | PDZ domain containing 2 |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RBKS | ribokinase |
| RPL23AP7 | ribosomal protein L23a pseudogene 7 |
| RPS2 | ribosomal protein S2 |
| SAP18 | Sin3A-associated protein, 18kDa |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) |
| SIAH2 | siah E3 ubiquitin protein ligase 2 |
| SLC33A1 | solute carrier family 33 (acetyl-CoA transporter), member 1 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 |
| SSR1 | signal sequence receptor, alpha |
| STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 |
| TES | testin LIM domain protein |
| TMED7 | transmembrane emp24 protein transport domain containing 7 |
| TMEM127 | transmembrane protein 127 |
| TOB2 | transducer of ERBB2, 2 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| ZBTB40 | zinc finger and BTB domain containing 40 |
| ZFR | zinc finger RNA binding protein |
| Symbol | Name |
|---|---|
| AKTIP | AKT interacting protein |
| AMT | aminomethyltransferase |
| ART3 | ADP-ribosyltransferase 3 |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 |
| ATP6V1G2 | ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 |
| BEAN1 | brain expressed, associated with NEDD4, 1 |
| BEX1 | brain expressed, X-linked 1 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CA6 | carbonic anhydrase VI |
| CARD8 | caspase recruitment domain family, member 8 |
| CCDC132 | coiled-coil domain containing 132 |
| CCDC176 | coiled-coil domain containing 176 |
| CCDC82 | coiled-coil domain containing 82 |
| CD177 | CD177 molecule |
| CD19 | CD19 molecule |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) |
| CD82 | CD82 molecule |
| CDK20 | cyclin-dependent kinase 20 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CHAF1B | chromatin assembly factor 1, subunit B (p60) |
| CHRM4 | cholinergic receptor, muscarinic 4 |
| CPB1 | carboxypeptidase B1 (tissue) |
| CSK | c-src tyrosine kinase |
| DAGLA | diacylglycerol lipase, alpha |
| DCC | DCC netrin 1 receptor |
| ENO3 | enolase 3 (beta, muscle) |
| EVPL | envoplakin |
| FBRS | fibrosin |
| FCGR1B | Fc fragment of IgG, high affinity Ib, receptor (CD64) |
| FOXF1 | forkhead box F1 |
| FOXJ1 | forkhead box J1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GBX2 | gastrulation brain homeobox 2 |
| GMPPA | GDP-mannose pyrophosphorylase A |
| GMPR | guanosine monophosphate reductase |
| GPR3 | G protein-coupled receptor 3 |
| GUCA2A | guanylate cyclase activator 2A (guanylin) |
| HDAC5 | histone deacetylase 5 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IFNA4 | interferon, alpha 4 |
| IL13 | interleukin 13 |
| IL17RA | interleukin 17 receptor A |
| INTS8 | integrator complex subunit 8 |
| KCNE1 | potassium channel, voltage gated subfamily E regulatory beta subunit 1 |
| KLHL25 | kelch-like family member 25 |
| LEMD3 | LEM domain containing 3 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LHPP | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| LOC441601 | septin 7 pseudogene |
| LRRC49 | leucine rich repeat containing 49 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MAGEC1 | melanoma antigen family C1 |
| MPPED1 | metallophosphoesterase domain containing 1 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MTG1 | mitochondrial ribosome-associated GTPase 1 |
| MTHFS | 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase) |
| NDRG4 | NDRG family member 4 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NINJ1 | ninjurin 1 |
| NLK | nemo-like kinase |
| NT5C | 5', 3'-nucleotidase, cytosolic |
| NTHL1 | nth endonuclease III-like 1 (E. coli) |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
| OLFML2A | olfactomedin-like 2A |
| OR12D3 | olfactory receptor, family 12, subfamily D, member 3 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PAK1IP1 | PAK1 interacting protein 1 |
| PDE6A | phosphodiesterase 6A, cGMP-specific, rod, alpha |
| PENK | proenkephalin |
| PFAS | phosphoribosylformylglycinamidine synthase |
| PICK1 | protein interacting with PRKCA 1 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PNOC | prepronociceptin |
| PPARG | peroxisome proliferator-activated receptor gamma |
| PPP1R26 | protein phosphatase 1, regulatory subunit 26 |
| PRODH2 | proline dehydrogenase (oxidase) 2 |
| PRSS21 | protease, serine, 21 (testisin) |
| RBM15 | RNA binding motif protein 15 |
| RMI1 | RecQ mediated genome instability 1 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SLC6A12 | solute carrier family 6 (neurotransmitter transporter), member 12 |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| SSTR4 | somatostatin receptor 4 |
| STRA6 | stimulated by retinoic acid 6 |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
| TMPRSS5 | transmembrane protease, serine 5 |
| TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B |
| TRAIP | TRAF interacting protein |
| TST | thiosulfate sulfurtransferase (rhodanese) |
| TULP2 | tubby like protein 2 |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 |
| ZNF280A | zinc finger protein 280A |
| ZNF606 | zinc finger protein 606 |
